Search Results - "OCHS, J"

Immobilization and Intracellular Delivery of an Anticancer Drug Using Mussel-Inspired Polydopamine Capsules by Cui, Jiwei, Yan, Yan, Such, Georgina K, Liang, Kang, Ochs, Christopher J, Postma, Almar, Caruso, Frank

“…We report a facile approach to immobilize pH-cleavable polymer-drug conjugates in mussel-inspired polydopamine (PDA) capsules for intracellular drug delivery…”
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Frequency Comb from a Single Driven Nonlinear Nanomechanical Mode by Ochs, J. S., Boneß, D. K. J., Rastelli, G., Seitner, M., Belzig, W., Dykman, M. I., Weig, E. M.

“…Phononic frequency combs have attracted increasing attention both as a qualitatively new type of nonlinear phenomena in vibrational systems and from the point…”
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Automation in cell and gene therapy manufacturing: from past to future by Moutsatsou, P., Ochs, J., Schmitt, R. H., Hewitt, C. J., Hanga, M. P.

“…As more and more cell and gene therapies are being developed and with the increasing number of regulatory approvals being obtained, there is an emerging and…”
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A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment by Funamoto, Kenichi, Zervantonakis, Ioannis K, Liu, Yuchun, Ochs, Christopher J, Kim, Choong, Kamm, Roger D

“…Low oxygen tensions experienced in various pathological and physiological conditions are a major stimulus for angiogenesis. Hypoxic conditions play a critical…”
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Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients With Non–Small Cell Lung Cancer: A Randomized Trial by Kris, Mark G, Natale, Ronald B, Herbst, Roy S, Lynch, Jr, Thomas J, Prager, Diane, Belani, Chandra P, Schiller, Joan H, Kelly, Karen, Spiridonidis, Harris, Sandler, Alan, Albain, Kathy S, Cella, David, Wolf, Michael K, Averbuch, Steven D, Ochs, Judith J, Kay, Andrea C

“…CONTEXT More persons in the United States die from non–small cell lung cancer (NSCLC) than from breast, colorectal, and prostate cancer combined. In…”
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Variation in costs of parasite resistance among natural host populations by Auld, S. K. J. R., Penczykowski, R. M., Housley Ochs, J., Grippi, D. C., Hall, S. R., Duffy, M. A.

“…Organisms that can resist parasitic infection often have lower fitness in the absence of parasites. These costs of resistance can mediate host evolution during…”
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Low-Fouling, Biofunctionalized, and Biodegradable Click Capsules by Ochs, Christopher J, Such, Georgina K, Städler, Brigitte, Caruso, Frank

“…We report the synthesis of covalently stabilized hollow capsules from biodegradable materials using a combination of click chemistry and layer-by-layer (LbL)…”
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Adaptation of the autostem robotic platform for gmp-compliant manufacture of bone marrow-derived mesenchymal stromal cells by Murphy, M, Ochs, J, Schmitt, R, Barry, F

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Plasticity, not genetic variation, drives infection success of a fungal parasite by Searle, C L, Ochs, J H, Cáceres, C E, Chiang, S L, Gerardo, N M, Hall, S R, Duffy, M A

“…Hosts strongly influence parasite fitness. However, it is challenging to disentangle host effects on genetic vs plasticity-driven traits of parasites, since…”
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Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay by Ochs, Meike J, Sorg, Bernd L, Pufahl, Laura, Grez, Manuel, Suess, Beatrix, Steinhilber, Dieter

“…5-Lipoxygenase (5-LO) catalyzes the two initial steps in the biosynthesis of leukotrienes (LT), a group of inflammatory lipid mediators derived from…”
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A retrospective analysis of the outcome of patients who have received two prior chemotherapy regimens including platinum and docetaxel for recurrent non-small-cell lung cancer by Massarelli, E, Andre, F, Liu, D.D, Lee, J.J, Wolf, M, Fandi, A, Ochs, J, Le Chevalier, T, Fossella, F, Herbst, R.S

“…With the availability of chemotherapy agents for first- and second-line treatment of advanced non-small-cell lung cancer (NSCLC), the patient population that…”
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The AUTOSTEM platform for closed manufacture of bone marrow-derived mesenchymal stromal cells using a closed, scalable and automated robotic system by Murphy, M, Barry, F, Leschke, C, Vaughan, B, Gentili, C, O'Dea, J, Ogourtsov, V, Rafiq, Q.A, Ochs, J, Kulik, M, Koenig, N

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MicroRNA Involved in Inflammation: Control of Eicosanoid Pathway by Ochs, Meike J, Steinhilber, Dieter, Suess, Beatrix

“…MicroRNAs (miRNAs) have emerged as important regulators in human physiological and pathological processes. Recent investigations implicated the involvement of…”
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Secondary brain tumors in children treated for acute lymphoblastic leukemia at St Jude Children's Research Hospital by Walter, A W, Hancock, M L, Pui, C H, Hudson, M M, Ochs, J S, Rivera, G K, Pratt, C B, Boyett, J M, Kun, L E

“…To evaluate the incidence of and potential risk factors for second malignant neoplasms of the brain following treatment for childhood acute lymphoblastic…”
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Oxygen levels in thermoplastic microfluidic devices during cell culture by Ochs, Christopher J, Kasuya, Junichi, Pavesi, Andrea, Kamm, Roger D

“…We developed a computational model to predict oxygen levels in microfluidic plastic devices during cell culture. This model is based on experimental evaluation…”
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Trauma-Informed Care by Forkey, Heather, Szilagyi, Moira, Kelly, Erin T, Duffee, James

“…Most children will experience some type of trauma during childhood, and many children suffer from significant adversities. Research in genetics, neuroscience,…”
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Dopamine-Mediated Continuous Assembly of Biodegradable Capsules by Ochs, Christopher J., Hong, Tam, Such, Georgina K., Cui, Jiwei, Postma, Almar, Caruso, Frank

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Generation of wave digital structures for networks containing multiport elements by Franken, D., Ochs, J., Ochs, K.

“…Most standard wave digital filters are derived from passive reference circuits, where only parallel and serial connections between one-port elements occur. In…”
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Biodegradable Click Capsules with Engineered Drug-Loaded Multilayers by Ochs, Christopher J, Such, Georgina K, Yan, Yan, van Koeverden, Martin P, Caruso, Frank

“…We report the modular assembly of a polymer−drug conjugate into covalently stabilized, responsive, biodegradable, and drug-loaded capsules with control over…”
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Mass Spectrometry-Based Proteomics Identifies UPF1 as a Critical Gene Expression Regulator in MonoMac 6 Cells by Ochs, Meike J, Ossipova, Elena, Oliynyk, Ganna, Steinhilber, Dieter, Suess, Beatrix, Jakobsson, Per-Johan

“…5-Lipoxygenase (5-LO) catalyzes the two initial steps in the biosynthesis of leukotrienes, a group of inflammatory lipid mediators derived from arachidonic…”
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