Search Results - "OCHI, Takehiro"

Effect of road transportation on the serum biochemical parameters of cynomolgus monkeys and beagle dogs by OCHI, Takehiro, YAMADA, Azusa, NAGANUMA, Yuki, NISHINA, Noriko, KOYAMA, Hironari

“…To determine the effect of long-distance (approximately 600 km) road transportation on the blood biochemistry of laboratory animals, we investigated the…”
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Anesthetic Effect of a Combination of Medetomidine-Midazolam-Butorphanol in Cynomolgus Monkeys (Macaca fascicularis) by OCHI, Takehiro, NISHIURA, Ippei, TATSUMI, Mitsuyoshi, HIRANO, Yoshimi, YAHAGI, Kouichi, SAKURAI, Yasuhiro, MATSUYAMA-FUJIWARA, Kanako, SUDO, Yuji, NISHINA, Noriko, KOYAMA, Hironari

“…The anesthetic effect of a combination of medetomidine, midazolam and butorphanol (Me-Mi-Bu) was evaluated in healthy cynomolgus monkeys. The Me-Mi-Bu…”
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Effect of new training technique on affinity of cynomolgus monkeys for animal care personnel by Nishimoto, Ai, Tachibana, Yuki, Takaura, Kaoru, Ochi, Takehiro, Koyama, Hironari

“…To confirm our hypothesis that the sex and age of cynomolgus monkeys influences the effect of training, we employed a new training technique designed to…”
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Effects of Transport Stress on Serum Alkaline Phosphatase Activity in Beagle Dogs by Ochi, Takehiro, Nishiura, Ippei, Tatsumi, Mitsuyoshi, Hirano, Yoshimi, Yahagi, Kouichi, Sakurai, Yasuhiro, Sudo, Yuji, Koyama, Hironari, Hagita, Yuichi, Fujimoto, Yoshikatsu, Kitamura, Shinji, Hashimoto, Hideki, Nakamura, Tomoya, Yamada, Asobi, Tanimoto, Masayoshi, Nishina, Noriko

“…Here, to determine the effects of transport stress on blood parameters in dogs, we investigated the changes in hematologic and serum chemical parameters in…”
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The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models by Ochi, Takehiro, Motoyama, Yukio, Goto, Toshio

“…The pharmacological profile of the analgesic agent, 1-[(4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl]-4-methylpiperazine hydrochloride (FR122047), was…”
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Differential effect of FR122047, a selective cyclo‐oxygenase‐1 inhibitor, in rat chronic models of arthritis by Ochi, Takehiro, Goto, Toshio

“…We investigated the effects of FR122047 (1‐[(4,5‐bis(4‐methoxyphenyl)‐2‐thiazoyl)carbonyl]‐4‐methylpiperazine hydrochloride), a selective cyclo‐oxygenase…”
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Interaction of Cognitive and Motivational Processes in Asymmetric Preferences for Gains and Losses by Sasaki, Hiroyuki, Hayashi, Yoichiro, Ochi, Takehiro

“…An experiment on repetitive decision-making was conducted to explore the interaction between cognitive and motivational processes in decision-making. The…”
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The antinociceptive effect of FR140423 in mice: involvement of spinal α2-adrenoceptors by Ochi, Takehiro, Goto, Toshio

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The antinociceptive effect induced by FR140423 is mediated through spinal 5-HT2A and 5-HT3 receptors by OCHI, Takehiro, GOTO, Toshio

“…The involvement of 5-HT receptors in the antinociceptive effect of FR140423, 3-(difluoromethyl)-1-(4-methoxyphenyl)-5-[4-(methylsulfinyl)phenyl]py razole, was…”
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FR143166 attenuates spinal pain transmission through activation of the serotonergic system by Ochi, Takehiro, Ohkubo, Yoshitaka, Mutoh, Seitaro

“…We investigated the antinociceptive effect of 1-(4-fluorophenyl)-3-methyl-5-[4-(methylsulfinyl)phenyl]pyrazole (FR143166) in the tail-pinch test in mice. The…”
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Anti-inflammatory and analgesic effects of a novel pyrazole derivative, FR140423 by Ochi, Takehiro, Jobo-Magari, Katsue, Yonezawa, Atsuo, Matsumori, Kanae, Fujii, Takashi

“…The pharmacological profile of a novel and newly discovered non-steroidal anti-inflammatory and analgesic compound,…”
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Studies on Anti-inflammatory Agents. VI. Synthesis and Pharmacological Properties of 2, 3-Diarylthiophenes by TSUJI, Kiyoshi, NAKAMURA, Katsuya, OGINO, Takashi, KONISHI, Nobukiyo, TOJO, Takashi, OCHI, Takehiro, SEKI, Nobuo, MATSUO, Masaaki

“…A series of novel 5-substituted-2, 3-diarylthiophenes has been synthesized and found to be active in the rat adjuvant arthritis (AA) model and/or in the…”
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Studies on Anti-inflammatory Agents. IV. Synthesis and Pharmacological Properties of 1, 5-Diarylpyrazoles and Related Derivatives by TSUJI, Kiyoshi, NAKAMURA, Katsuya, KONISHI, Nobukiyo, TOJO, Takashi, OCHI, Takehiro, SENOH, Hachiro, MATSUO, Masaaki

“…A series of novel 1, 5-diarylpyrazole derivatives was synthesized and tested for anti-inflammatory and analgesic activities to develop anti-inflammatory agents…”
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Role of cyclooxygenase-2, but not cyclooxygenase-1, on type II collagen-induced arthritis in DBA/1J mice by Ochi, Takehiro, Ohkubo, Yoshitaka, Mutoh, Seitaro

“…The purpose of this paper is to explore the contribution of isoforms of cyclooxygenase (COX) to chronic inflammation in DBA/1J mice with type II…”
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Studies on Anti-inflammatory Agents. V. Synthesis and Pharmacological Properties of 3-(Difluoromethyl)-1-(4-methoxyphenyl)-5-(4-(methylsulfinyl)phenyl)pyrazole and Related Compounds by TSUJI, Kiyoshi, KONISHI, Nobukiyo, SPEARS, Glen W., OGINO, Takashi, NAKAMURA, Katsuya, TOJO, Takashi, OCHI, Takehiro, SHIMOJO, Fumio, SENOH, Hachiro, MATSUO, Masaaki

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The antinociceptive effect of FR140423 in mice: involvement of spinal α 2-adrenoceptors by Ochi, Takehiro, Goto, Toshio

“…We investigated the role of the spinal noradrenergic system in the antinociceptive effect of FR140423,…”
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The antinociceptive effect induced by FR140423 is mediated through spinal 5-HT 2A and 5-HT 3 receptors by Ochi, Takehiro, Goto, Toshio

“…The involvement of 5-HT receptors in the antinociceptive effect of FR140423, 3-(difluoromethyl)-1-(4-methoxyphenyl)-5-[4-(methylsulfinyl)phenyl]pyrazole, was…”
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The Anti-inflammatory Effect of FR188582, a Highly Selective Inhibitor of Cyclooxygenase-2, With an Ulcerogenic Sparing Effect in Rats by Ochi, Takehiro, Yamane-Sugiyama, Aiko, Ohkubo, Yoshitaka, Sakane, Kazuo, Tanaka, Hirokazu

“…The anti-inflammatory and ulcerogenic effects of FR188582, 3-chloro-5-[4-(methylsulfonyl) phenyl]-1-phenyl-1H-pyrazole, were investigated. In a recombinant…”
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Anti-inflammatory and analgesic effects of FK3311, a selective inhibitor of cyclooxygenase in inflamed tissues by Ochi, Takehiro, Senoh, Hachiro

“…FK3311 (4'acetyl-2'-「2, 4-difluorophenoxy」 methanesulfonanilide), is a neutral non-steroidal anti-inflammatory compound with improved gastrointestinal…”
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The participation of arachidonic acid metabolites in cargeenan-induced inflammation and hyperalgesia by Ochi, Takehiro, Senoh, Hachiro

“…We studied the role of arachidonic acid metabolites in cargeenan-induced edama and hyperalgesia. Injection of cargeenan into the rat paws resulted in edema and…”
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