Search Results - "OCHAION, A"

CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver by Cohen, S., Stemmer, S.M., Zozulya, G., Ochaion, A., Patoka, R., Barer, F., Bar-Yehuda, S., Rath-Wolfson, L., Jacobson, K.A., Fishman, P.

“…The Gi protein‐associated A3 adenosine receptor (A3AR) is a member of the adenosine receptor family. Selective agonists at the A3AR, such as CF101 and CF102…”
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The A3 adenosine receptor agonist CF102 induces apoptosis of hepatocellular carcinoma via de-regulation of the Wnt and NF-κB signal transduction pathways by BAR-YEHUDA, S, STEMMER, S. M, FISHMAN, P, MADI, L, CASTEL, D, OCHAION, A, COHEN, S, BARER, F, ZABUTTI, A, PEREZ-LIZ, G, DELVALLE, L

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The anti-inflammatory target A(3) adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn's disease by Ochaion, A, Bar-Yehuda, S, Cohen, S, Barer, F, Patoka, R, Amital, H, Reitblat, T, Reitblat, A, Ophir, J, Konfino, I, Chowers, Y, Ben-Horin, S, Fishman, P

“…The Gi protein associated A(3) adenosine receptor (A(3)AR) was recently defined as a novel anti-inflammatory target. The aim of this study was to look at…”
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The anti-inflammatory target A3 adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn’s disease by Ochaion, A., Bar-Yehuda, S., Cohen, S., Barer, F., Patoka, R., Amital, H., Reitblat, T., Reitblat, A., Ophir, J., Konfino, I., Chowers, Y., Ben-Horin, S., Fishman, P.

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The As adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-κB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats by OCHAION, A, BAR-YEHUDA, S, PEREZ-LIZ, G, FISHMAN, P, COHEN, S, AMITAL, H, JACOBSON, K. A, JOSHI, B. V, GAO, Z. G, BARER, F, PATOKA, R, DEL VALLE, L

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924 CF102 INDUCES APOPTOSIS OF LIVER CANCER WHILE PREVENTING APOPTOSIS IN LIVER INFLAMMATION: A NEW APPROACH TO TREAT LIVER DISEASES by Cohen, S, Stemmer, S.M, Zozulya, G, Ochaion, A, Patoka, R, Barer, F, Bar Yehuda, S, Rath-Wolfson, L, Fishman, P

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Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment by Bar‐Yehuda, S., Rath‐Wolfson, L., Del Valle, L., Ochaion, A., Cohen, S., Patoka, R., Zozulya, G., Barer, F., Atar, E., Piña‐Oviedo, S., Perez‐Liz, G., Castel, D., Fishman, P.

“…Objective Studies have suggested that rheumatoid arthritis (RA) and osteoarthritis (OA) share common characteristics. The highly selective A3 adenosine…”
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The A3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-κB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats by Ochaion, A., Bar-Yehuda, S., Cohen, S., Amital, H., Jacobson, K.A., Joshi, B.V., Gao, Z.G., Barer, F., Patoka, R., Del Valle, L., Perez-Liz, G., Fishman, P.

“…The A 3 adenosine receptor (A 3 AR) is over-expressed in inflammatory cells and was defined as a target to combat inflammation. Synthetic agonists to this…”
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The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis by Fishman, Pnina, Bar-Yehuda, Sara, Madi, Lea, Rath-Wolfson, Lea, Ochaion, Avivit, Cohen, Shira, Baharav, Ehud

“…Abstract The anti-inflammatory effect of adenosine was previously found to be mediated via activation of the A 3 adenosine receptor (A 3 AR). The aim of the…”
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A3 adenosine receptor activation in melanoma cells: association between receptor fate and tumor growth inhibition by Madi, Lea, Bar-Yehuda, Sara, Barer, Faina, Ardon, Eti, Ochaion, Avivit, Fishman, Pnina

“…Activation of the Gi protein-coupled A3 adenosine receptor (A3AR) has been implicated in the inhibition of melanoma cell growth by deregulating protein kinase…”
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CF102 an A 3 adenosine receptor agonist mediates anti‐tumor and anti‐inflammatory effects in the liver by Cohen, S., Stemmer, S.M., Zozulya, G., Ochaion, A., Patoka, R., Barer, F., Bar‐Yehuda, S., Rath‐Wolfson, L., Jacobson, K.A., Fishman, P.

“…Abstract The Gi protein‐associated A 3 adenosine receptor (A 3 AR) is a member of the adenosine receptor family. Selective agonists at the A 3 AR, such as…”
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Targeting the A3 adenosine receptor for cancer therapy: inhibition of prostate carcinoma cell growth by A3AR agonist by Fishman, Pnina, Bar-Yehuda, Sara, Ardon, Eti, Rath-Wolfson, Lea, Barrer, Faina, Ochaion, Avivit, Madi, Lea

“…Agonists to A3 adenosine receptor (A3AR) were shown to inhibit the growth of various tumor cell types. The present study demonstrates that a synthetic A3AR…”
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IB-MECA, an A3 adenosine receptor agonist prevents bone resorption in rats with adjuvant induced arthritis by RATH-WOLFSON, L, BAR-YEHUDA, S, MADI, L, OCHAION, A, COHEN, S, ZABUTTI, A, FISHMAN, P

“…The anti-inflammatory effect of adenosine is partially mediated via the A3 adenosine receptor (A3AR), a Gi protein associated cell surface receptor. The highly…”
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Agonists to the A3 adenosine receptor induce G-CSF production via NF-κB activation: A new class of myeloprotective agents by Bar-Yehuda, Sara, Madi, Lea, Barak, Dana, Mittelman, Moshe, Ardon, Eti, Ochaion, Avivit, Cohn, Shira, Fishman, Pnina

“…The aim of this study was to evaluate the effect of CF101, a synthetic agonist to the A3 adenosine receptor (A3AR), on the production of granulocyte…”
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Over-expression of the A 3 adenosine receptor in tumor and PBMC of hepatocellular carcinoma patients: A specific therapeutic target by Fishman, P., Stemmer, S., Castel, D., Ochaion, A., Cohn, S., Barer, F., Zabutti, A., Bar Yehuda, S.

“…Abstract only 14085 Background: The Gi protein associated A 3 adenosine receptor (A 3 AR) is highly expressed in colon carcinoma tissue and is reflected in…”
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Effect of CF102 on growth suppression and apoptosis in an orthotopic model of hepatocellular carcinoma by Bar Yehuda, S., Stemmer, S. M., Madi, L., Castel, D., Ochaion, A., Cohen, S., Barer, F., Perez-Liz, G., Del Valle, L., Fishman, P.

“…Abstract only…”
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The A 3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-κB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats by Ochaion, A., Bar-Yehuda, S., Cohen, S., Amital, H., Jacobson, K.A., Joshi, B.V., Gao, Z.G., Barer, F., Patoka, R., Del Valle, L., Perez-Liz, G., Fishman, P.

“…The A 3 adenosine receptor (A 3AR) is over-expressed in inflammatory cells and was defined as a target to combat inflammation. Synthetic agonists to this…”
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The A3 adenosine receptor agonist CF102 induces apoptosis of hepatocellular carcinoma via de-regulation of the Wnt and NF-kappaB signal transduction pathways by Bar-Yehuda, S, Stemmer, S M, Madi, L, Castel, D, Ochaion, A, Cohen, S, Barer, F, Zabutti, A, Perez-Liz, G, Del Valle, L, Fishman, P

“…The A3 adenosine receptor (A(3)AR) is highly expressed in tumors and was suggested as a target for cancer treatment. In this study, we show that A(3)AR is…”
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The anti-inflammatory target A sub(3) adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn's disease by Ochaion, A, Bar-Yehuda, S, Cohen, S, Barer, F, Patoka, R, Amital, H, Reitblat, T, Reitblat, A, Ophir, J, Konfino, I, Chowers, Y, Ben-Horin, S, Fishman, P

“…The Gi protein associated A sub(3) adenosine receptor (A sub(3)AR) was recently defined as a novel anti-inflammatory target. The aim of this study was to look…”
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The anti-inflammatory target A 3 adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn’s disease by Ochaion, A., Bar-Yehuda, S., Cohen, S., Barer, F., Patoka, R., Amital, H., Reitblat, T., Reitblat, A., Ophir, J., Konfino, I., Chowers, Y., Ben-Horin, S., Fishman, P.

“…The Gi protein associated A 3 adenosine receptor (A 3AR) was recently defined as a novel anti-inflammatory target. The aim of this study was to look at A 3AR…”
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