Search Results - "OAKLEY, Miranda"

Molecular Factors and Biochemical Pathways Induced by Febrile Temperature in Intraerythrocytic Plasmodium falciparum Parasites by Oakley, Miranda S.M, Kumar, Sanjai, Anantharaman, Vivek, Zheng, Hong, Mahajan, Babita, Haynes, J. David, Moch, J. Kathleen, Fairhurst, Rick, McCutchan, Thomas F, Aravind, L

“…Intermittent episodes of febrile illness are the most benign and recognized symptom of infection with malaria parasites, although the effects on parasite…”
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TCRβ-expressing macrophages induced by a pathogenic murine malaria correlate with parasite burden and enhanced phagocytic activity by Oakley, Miranda S, Chorazeczewski, Joanna K, Aleshnick, Maya, Anantharaman, Vivek, Majam, Victoria, Chawla, Bhavna, Myers, Timothy G, Su, Qin, Okoth, Winter A, Takeda, Kazuyo, Akue, Adovi, KuKuruga, Mark, Aravind, L, Kumar, Sanjai

“…Macrophages express a wide array of invariant receptors that facilitate host defense and mediate pathogenesis during pathogen invasion. We report on a novel…”
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CD47 blockade reduces the pathologic features of experimental cerebral malaria and promotes survival of hosts with Plasmodium infection by Dulgeroff, Laughing Bear Torrez, Oakley, Miranda S., Tal, Michal C., Yiu, Ying Ying, He, Joy Q., Shoham, Maia, Majam, Victoria, Okoth, Winter A., Malla, Pallavi, Kumar, Sanjai, Weissman, Irving L.

“…CD47 is an antiphagocytic “don’t eat me” signal that inhibits programmed cell removal of self. As red blood cells (RBCs) age they lose CD47 expression and…”
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Technologies for Detection of Babesia microti : Advances and Challenges by Meredith, Scott, Oakley, Miranda, Kumar, Sanjai

“…The biology of intraerythrocytic parasites presents unique challenges for the diagnosis of human babesiosis. Antibody-based assays are highly sensitive but…”
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Molecular Markers of Radiation Induced Attenuation in Intrahepatic Plasmodium falciparum Parasites by Oakley, Miranda S, Verma, Nitin, Zheng, Hong, Anantharaman, Vivek, Takeda, Kazuyo, Gao, Yamei, Myers, Timothy G, Pham, Phuong Thao, Mahajan, Babita, Kumar, Nirbhay, Sangweme, Davison, Tripathi, Abhai K, Mlambo, Godfree, Aravind, L, Kumar, Sanjai

“…Experimental immunization with radiation attenuated sporozoites (RAS) and genetically attenuated sporozoites has proved to be a promising approach for malaria…”
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Clinical and molecular aspects of malaria fever by Oakley, Miranda S, Gerald, Noel, McCutchan, Thomas F, Aravind, L, Kumar, Sanjai

“…Although clinically benign, malaria fever is thought to have significant relevance in terms of parasite growth and survival and its virulence which in turn may…”
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TCRβ Combinatorial Immunoreceptor Expression by Neutrophils Correlates with Parasite Burden and Enhanced Phagocytosis during a Plasmodium berghei ANKA Malaria Infection by Chorazeczewski, Joanna K, Aleshnick, Maya, Majam, Victoria, Okoth, Winter A, Kurapova, Regina, Akue, Adovi, Kukuruga, Mark, Kumar, Sanjai, Oakley, Miranda S

“…Recent studies have demonstrated that a subpopulation of neutrophils express the TCRαβ combinatorial immunoreceptor in humans and mice. Here, we report that a…”
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Plasmodium falciparum Pf77 and male development gene 1 as vaccine antigens that induce potent transmission-reducing antibodies by Tripathi, Abhai K, Oakley, Miranda S, Verma, Nitin, Mlambo, Godfree, Zheng, Hong, Meredith, Scott M, Essuman, Edward, Puri, Ankit, Skelton, Richard A, Takeda, Kazuyo, Majam, Victoria, Quakyi, Isabella A, Locke, Emily, Morin, Merribeth, Miura, Kazutoyo, Long, Carole A, Kumar, Sanjai

“…Malaria vaccines that disrupt the life cycle in mosquitoes and reduce parasite transmission in endemic areas are termed transmission-blocking vaccines (TBVs)…”
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A Novel Gametocyte Biomarker for Superior Molecular Detection of the Plasmodium falciparum Infectious Reservoirs by Essuman, Edward, Grabias, Bryan, Verma, Nitin, Chorazeczewski, Joanna K., Tripathi, Abhai K., Mlambo, Godfree, Addison, Ebenezer A., Amoah, Albert G. B., Quakyi, Isabella, Oakley, Miranda S., Kumar, Sanjai

“…We have identified a superior diagnostic biomarker, Pfg17, for detecting asymptomatic reservoirs otherwise missed by the most sensitive molecular method…”
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Transcriptome analysis based detection of Plasmodium falciparum development in Anopheles stephensi mosquitoes by Oakley, Miranda S., Verma, Nitin, Myers, Timothy G., Zheng, Hong, Locke, Emily, Morin, Merribeth J., Tripathi, Abhai K., Mlambo, Godfree, Kumar, Sanjai

“…The Plasmodium life cycle within the mosquito involves the gamete, zygote, motile ookinete, and the oocyst stage that supports sporogony and sporozoite…”
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The transcription factor T-bet regulates parasitemia and promotes pathogenesis during Plasmodium berghei ANKA murine malaria by Oakley, Miranda S, Sahu, Bikash R, Lotspeich-Cole, Leda, Solanki, Nehal R, Majam, Victoria, Pham, Phuong Thao, Banerjee, Rajdeep, Kozakai, Yukiko, Derrick, Steven C, Kumar, Sanjai, Morris, Sheldon L

“…The pathogenesis of experimental cerebral malaria (ECM) is an immunologic process, mediated in part by Th1 CD4(+) T cells. However, the role of the Th1 CD4(+)…”
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Pathogenic roles of CD14, galectin-3, and OX40 during experimental cerebral malaria in mice by Oakley, Miranda S, Majam, Victoria, Mahajan, Babita, Gerald, Noel, Anantharaman, Vivek, Ward, Jerrold M, Faucette, Lawrence J, McCutchan, Thomas F, Zheng, Hong, Terabe, Masaki, Berzofsky, Jay A, Aravind, L, Kumar, Sanjai

“…An in-depth knowledge of the host molecules and biological pathways that contribute towards the pathogenesis of cerebral malaria would help guide the…”
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Immune Control in Repeated Babesia microti Infection in a Patient With B-Cell Deficiency by Little, Jessica S, Oakley, Miranda S, Thorner, Anna R, Johnston, Demerise, Majam, Victoria, Liakos, Alexis D, Novack, Lewis A, Zheng, Hong, Meredith, Scott, Chou, Chao-Kai, Newton, Benjamin R, Soiffer, Robert J, Krause, Peter J, Baden, Lindsey R, Kumar, Sanjai

“…The immunology of human babesiosis is poorly investigated. We present a comprehensive investigation of a 75-year-old man with B-cell deficiency who experienced…”
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T‐bet modulates the antibody response and immune protection during murine malaria by Oakley, Miranda S., Sahu, Bikash R., Lotspeich‐Cole, Leda, Majam, Victoria, Thao Pham, Phuong, Sengupta Banerjee, Aditi, Kozakai, Yukiko, Morris, Sheldon L., Kumar, Sanjai

“…CD4+ T‐cell subtypes govern the synthesis of different Ab isotypes and other immune functions. The influence of CD4+ T‐cell differentiation programs on isotype…”
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Radiation-Induced Cellular and Molecular Alterations in Asexual Intraerythrocytic Plasmodium falciparum by Oakley, Miranda S., Gerald, Noel, Anantharaman, Vivek, Gao, Yamei, Majam, Victoria, Mahajan, Babita, Pham, Phuong Thao, Lotspeich-Cole, Leda, Myers, Timothy G., McCutchan, Thomas F., Morris, Sheldon L., Aravind, L., Kumar, Sanjai

“…Background, γ-irradiation is commonly used to create attenuation in Plasmodium parasites. However, there are no systematic studies on the survival, reversion…”
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Molecular Correlates of Experimental Cerebral Malaria Detectable in Whole Blood by Oakley, Miranda S, Anantharaman, Vivek, Venancio, Thiago M, Zheng, Hong, Mahajan, Babita, Majam, Victoria, McCutchan, Thomas F, Myers, Timothy G, Aravind, L, Kumar, Sanjai

“…Cerebral malaria (CM) is a primary cause of deaths caused by Plasmodium falciparum in young children in sub-Saharan Africa. Laboratory tests based on early…”
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Host Biomarkers and Biological Pathways That Are Associated with the Expression of Experimental Cerebral Malaria in Mice by Oakley, Miranda S, McCutchan, Thomas F, Anantharaman, Vivek, Ward, Jerrold M, Faucette, Laurence, Erexson, Cindy, Mahajan, Babita, Zheng, Hong, Majam, Victoria, Aravind, L, Kumar, Sanjai

“…Cerebral malaria (CM) is a primary cause of malaria-associated deaths among young African children. Yet no diagnostic tools are available that could be used to…”
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Malaria infections do not compromise vaccine-induced immunity against tuberculosis in mice by Parra, Marcela, Derrick, Steven C, Yang, Amy, Tian, Jinhua, Kolibab, Kristopher, Oakley, Miranda, Perera, Liyanage P, Jacobs, William R, Kumar, Sanjai, Morris, Sheldon L

“…Given the considerable geographic overlap in the endemic regions for malaria and tuberculosis, it is probable that co-infections with Mycobacterium…”
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CpG Oligodeoxynucleotide and Montanide ISA 51 Adjuvant Combination Enhanced the Protective Efficacy of a Subunit Malaria Vaccine by KUMAR, Sanjai, JONES, Trevor R, OAKLEY, Miranda S, HONG ZHENG, KUPPUSAMY, Shanmuga P, TAYE, Alem, KRIEG, Arthur M, STOWERS, Anthony W, KASLOW, David C, HOFFMAN, Stephen L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Protective efficacy and correlates of immunity of immunodominant recombinant Babesia microti antigens by Meredith, Scott, Majam, Victoria, Zheng, Hong, Verma, Nitin, Puri, Ankit, Akue, Adovi, KuKuruga, Mark, Oakley, Miranda, Kumar, Sanjai

“…Babesia microti, an intraerythrocytic apicomplexan parasite, is the primary causative agent of human babesiosis and an emerging threat to public health in the…”
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