TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSIS

The study of thrombocyte parameteres in healthy women in reproductive age (n=29) and pregnant women in third trimester with normal ongoing pregnancy (n=20) and with gestosis (n=38) was conducted. The relative breadth of distribution by volume(PDW, fl), share of cells with volume more than 12 fl (P-L...

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Bibliographic Details
Published in:	Акушерство, гинекология и репродукция Vol. 6; no. 3; pp. 28 - 33
Main Authors:	V. M. Pogorelov, G. I. Kozinec, I. O. Makarov, A. V. Tochenov, O. V. Rykunova
Format:	Journal Article
Language:	Russian
Published:	IRBIS LLC 01-09-2016
Subjects:	gestosis immature platelet forms pregnancy trombopoesis
Online Access:	Get full text
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Summary:	The study of thrombocyte parameteres in healthy women in reproductive age (n=29) and pregnant women in third trimester with normal ongoing pregnancy (n=20) and with gestosis (n=38) was conducted. The relative breadth of distribution by volume(PDW, fl), share of cells with volume more than 12 fl (P-LCR, %) and relative quantity of immature thrombocytes (IPF, %) were investigated. It was established that significant decrease of thrombocytes number takes place in pregnants compared to healthy women of reproductive age. The most significant changes were observed in women with moderate and severe gestosis. The reliable increase of relative breadth of thrombocyte distribution by volume in this group of pregnant women was also detected. This may be associated with growth of number of big and, probably, immature and functionally active thrombocytes. Thus, increase in number of immature thrombocytes, occurring in response to endothelium lesions as a part of gestosis pathogenesis, may serve as adaptation marker of thrombopoeisis system.
ISSN:	2313-7347 2500-3194