GASTRIC CANCER: MOLECULAR AND GENETIC DATA (LITERATURE REVIEW)

In the review a data about molecular and genetic aspects of different morphological variants of gastric cancer in population and family studies are generalized. Data about multiple genetic and epigenetic damages in oncogenes, tumor suppressor genes, cell cycle regulators, adhesion molecules, DNA rep...

Full description

Saved in:

Bibliographic Details
Published in:	Sibirskiĭ onkologicheskiĭ zhurnal no. 2; pp. 56 - 64
Main Authors:	A. V. Belkovets, O. V. Reschetnikov, S. A. Kurilovich, V. N. Maksimov
Format:	Journal Article
Language:	Russian
Published:	Russian Academy of Sciences, Tomsk National Research Medical Center 01-02-2016
Subjects:	diagnosis gastric cancer gene mutations genetic predisposition
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	In the review a data about molecular and genetic aspects of different morphological variants of gastric cancer in population and family studies are generalized. Data about multiple genetic and epigenetic damages in oncogenes, tumor suppressor genes, cell cycle regulators, adhesion molecules, DNA repair genes as well as genetic instability and telomerase activation involved in the multistep process of carcinogenesis and making a contribution to uncontrolled growth and ability to form metastases are included in the review. In article possibilities of use of specific molecular markers for early GC diagnostics are discussed.
ISSN:	1814-4861 2312-3168