Search Results - "O. S. Zaichenko"

Investigation of the Planar Structures of Quantum Functional Polymeric Nanolayers on Polybenzimidazole Fiber Nanosheets by Balaban, O. V., Grygorchak, I. I., Kondyr, A. I., Zaichenko, O. S., Mitina, N. E., Datsyuk, V. V., Trotsenko, S. E., M’yahkota, O. S.

“…Two-dimensional nanofiber mats based on a mixture of polybenzimidazole with telechelic oligoperoxide are obtained by the method of electrospinning. It is shown…”
Get full text

Genetic transformation of moss Ceratodon purpureus by means of polycationic carriers of DNA by Finiuk, N. S, Chaplya, A. Y, Mitina, N. Y, Boiko, N. M, Lobachevska, O. V, Miahkota, O. S, Yemets, A. I, Blume, Ya. B, Zaichenko, O. S, Stoika, R. S

“…There is much progress in application of genetic engineering for improving the biological properties of different organisms. Viral and nonviral carriers are…”
Get full text

Effect of a novel thiazole derivative and its complex with polymeric carriers on the activity of antioxidant enzymes in murine lymphoma cells by Popovych, M. V., Shalai, Ya. R., Mandzynets, S. M., Mitina, N. E., Zaichenko, O. S., Babsky, A. M.

“…Background. Previous studies have shown a pronounced cytotoxic effect of thiazole derivatives in combination with polymeric carriers on tumor cells. At the…”
Get full text

Antineoplastic Activity In Vitro of 2-amino-5-benzylthiasol Derivative in the Complex with Nanoscale Polymeric Carriers by Finiuk, N. S., Popovych, M. V., Shalai, Ya. R., Mandzynets’, S. M., Hreniuh, V. P., Ostapiuk, Yu. V., Obushak, M. D., Mitina, N. E., Zaichenko, O. S., Stoika, R. S., Babsky, A. M.

“…The main problems of contemporary chemotherapy are the insufficient efficacy of antitumor drugs and low selectivity of their action, development of multidrug…”
Get full text

Effect of a novel thiazole derivative and its complex with a polymeric carrier on stability of DNA in human breast cancer cells by Finiuk, N. S., Klyuchivska, O. Yu, Ivasechko, I. I., Mitina, N. E., Ostapiuk, Yu. V., Obushak, M. D., Zaichenko, O. S., Babsky, A. M., Stoika, R. S.

“…Thiazole derivatives are perspective antitumor compounds characterized by a broad range of bioactivity, while polymeric carriers are widely used to enhance the…”
Get full text

Safety profile of thiazole derivative and its complex with PEG-based polymeric nanoparticles on liver and blood cells in tumor-bearing mice by Ilkiv, M. V., Shalai, Ya. R., Ostapiuk, Yu. V., Mitina, N. E., Zaichenko, O. S., Babsky, A. M.

“…Background. Drug delivery systems (DDS) have demonstrated a significant ability to overcome many of the challenges associated with the delivery of hydrophobic…”
Get full text

Effect of thiazole derivative complexed with nanoscale polymeric carriers on cellular ultrastructure of murine lymphoma cells in vivo by Popovych, M. V., Shalai, Ya. R., Hreniukh, V. P., Kulachkovskyy, O. R., Mandzynets, S. M., Mitina, N. E., Zaichenko, O. S., Babsky, A. M.

“…Background. A pronounced cytotoxic action of the thiazole derivatives complexed with polymeric carriers on tumor cells in vitro was reported earlier, while no…”
Get full text

Modern radiation therapy in part of treatment primary mediastinal (thymic) B-large cell lymphoma (results of 131 patients treated at N.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation) by Trofimova, O P, Zavodnova, I Z, Tumyan, G S, Pryamikova, Yu I, Volkova, N V, Zaichenko, O S, Nazarenko, A V

“…Background. For many decades of the twentieth century, radiation therapy has played a leading role in the treatment of patients with lymphoproliferative…”
Get full text

BIOCHEMICAL INDICATORS OF HEPATOTOXICITY IN BLOOD SERUM OF RATS UNDER THE EFFECT OF NOVEL 4-THIAZOLIDINONE DERIVATIVES AND DOXORUBICIN AND THEIR COMPLEXES WITH POLYETHYLENEGLYCOL-CONTAINING NANOSCALE POLYMERIC CARRIER by Kobylinska, L I, Havrylyuk, D Ya, Ryabtseva, A O, Mitina, N E, Zaichenko, O S, Lesyk, R B, Zimenkovsky, B S, Stoika, R S

“…The aim of this study was to compare the effect of new synthetic 4-tiazolidinone derivatives (compounds 3882, 3288 and 3833) and doxorubicin (positive control)…”
Get full text

Study of rat blood serum biochemical indicators of cardiotoxic action of novel antitumor 4-thiazolidinone derivatives and doxorubicin in complexes with polyethylene glycol-containing polymeric carrier in the rat blood serum by Kobylyns'ka, L I, Havryliuk, D Ia, Riabtseva, A O, Mitina, N Ie, Zaichenko, O S, Zimenkovskyĭ, B S, Stoĭka, R S

“…The aim of this study was to measure the activity of enzymes which reflect cardiotoxic action in rats of novel synthetic 4-thiazolidone derivatives--3882, 3288…”
Get more information

VITALITY AND MORPHOLOGY OF TUMOR CELLS TREATED WITH 4-TIAZOLIDINONE DERIVATIVES IMMOBILIZED ON NANOSCALE POLYMER CARRIER by Boiko, N M, Klyuchivska, O Yu, Kobylinska, L I, Havrylyuk, D Ya, Ryabtseva, A O, Mitina, N Ye, Lesyk, R B, Zàichenko, O S, Stoika, R S

“…A nanoscale polymeric carrier was used for delivery of novel anticancer compounds -- 4-tiazolidinone derivatives -- to tumor cells of different lines. It was…”
Get full text

Evaluation of cytotoxic and mutagenic action of novel surface active comb-like polyampholytes that are used for delivery of nucleic acids to target cells by Finiuk, N. S., Filyak, Y. Z., Boiko, N. M., Mitina, N. Y., Zaichenko, O. S., Stoika, R. S.

“…Rapid development of new nanomaterials and nanotechnologies is accompanied by significant achievements in various fields of medicine, industry and precise…”
Get full text

Functions of metallothioneins and a system of antioxidant defense under the effect of Co- and Zn-containing nanocomposites on crucian carp (Carassius auratus gibelio) by H. I. Falfushynska, L. L. Gnatyshyna, O. O. Turta, O. B. Stoliar, N. E. Mitina, O. S. Zaichenko, R. S. Stoika

“…The effect of metal-nanocomposites (Me-NC) of cobalt and zinc (Co- and Zn-NC, correspondingly) synthecized on the basis of vinylpyrrolidone (PS) on the…”
Get full text

Immobilization of doxorubicin on the olygoelectrolytic polymeric carrier VEP-GMA-PEG increases its and anticancer activity cellular uptake by Senkiv, Yu. V., Ryabtseva, A. R., Heffeter, P., Boiko, N. M., Shlyakhtina, E. A., Mitina, N. E., Berger, W., Zaichenko, O. S., Stoika, R. S.

“…Application of special systems for drug delivery into target cells might be useful for overcoming several problems in treatment of dangerous diseases. These…”
Get full text

Histomorphology of organs and activity of some enzymes in mice after immunization with polymer based on acrylic acid or aluminum hydroxide as adjuvants by Kozak, M. R., Martyn, Yu.V., Oliynyk, A. V., Kuzmina, N. V., Ostapiv, D. D., Pajuk, O. L., Mitina, N. E., Zaichenko, O. S., Vlizlo, V. V.

Get full text

Modulation of temozolomide action towards rat and human glioblastoma cells in vitro by its combination with doxorubicin and immobilization with nanoscale polymeric carrier by N. S. Finiuk, J. V. Senkiv, A. O. Riabtseva, N. Y. Mitina, N. I. Molochii, M. O. Kitsera, S. S. Avdieiev, O. S. Zaichenko, R. S. Stoika

“…Malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) occur more frequently than other types of primary central nervous system tumors, having…”
Get full text

Adjuvant properties of polymer based on acrylic acid by M. R. Kozak, A. V. Oliynyk, O. S. Zaichenko, V. V. Vlizlo

“…Adjuvant properties of the polymer containing­ acrylic acid, glycidyl methacrylate, triethylene glycol methacrylate and butyl acrylate have been established…”
Get full text

Action of free and polymer carrier encapsulated doxorubicin towards HCT116 cells of human colorectal carcinoma by Yu. V. Senkiv, P. Heffeter, A. O. Riabtseva, N. M. Boiko, O. S. Zaichenko, N. Ye. Mitina, W. Berger, R. S. Stoika

“…Development of novel nanoscale functionali­zed carriers is nowadays one of the most urgent problems in cancer treatment. The aim of our study was to compare…”
Get full text

Genetic transformation of the moss Ceratodon purpureus by novel polycationic carriers of DNA by Finiuk, N S, Chaplia, A Ie, Mitina, N Ie, Boĭko, N M, Lobachevs'ka, O V, M'iahkota, O S, Iemets', A I, Blium, Ia B, Zaichenko, O S, Stoĭka, R S

“…There is a big progress in application of genetic engineering for improving the biological properties of different organisms. Viral and non-viral carriers are…”
Get more information

POLYPLEX FORMATION BY NOVEL SURFACE ACTIVE COMB-LIKE POLYAMFOLYTES AND PLASMID DNA by Finiuk, N S, Vitak, T Y, Mitina, N Y, Filyak, Y Z, Zaichenko, O S, Stoika, R S

“…Formation of the interpolyelectrolytic complexes (polyplexes) of plasmid DNA and novel surface active comb-like polyampholytic carriers was studied. To do…”
Get full text