Search Results - "O Brien, John"
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Quantitative electroencephalography as a marker of cognitive fluctuations in dementia with Lewy bodies and an aid to differential diagnosis
Published in Clinical neurophysiology (01-06-2018)“…•EEG slowing was evident in dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) and less in Alzheimer’s disease (AD) patients compared to…”
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Characterizing ER Retention Defects of PDZ Binding Deficient Cx36 Mutants Using Confocal Microscopy
Published in Bio-protocol (20-07-2024)“…Overexpression of proteins in transiently transfected cells is a simple way to study basic transport mechanisms and the underlying protein-protein…”
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Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia
Published in Neurobiology of aging (01-07-2020)“…The hippocampus is one of the first regions to demonstrate atrophy during the prodromal stage of Alzheimer's disease. Volumetric analysis of its individual…”
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Synaptic Loss in Frontotemporal Dementia Revealed by [11C]UCB‐J Positron Emission Tomography
Published in Annals of neurology (01-01-2023)“…Objective Synaptic loss is an early feature of neurodegenerative disease models, and is severe in post mortem clinical studies, including frontotemporal…”
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C–C Coupling in sterically demanding porphyrin environments
Published in Beilstein journal of organic chemistry (04-11-2024)“…Unlike their planar counterparts, classic synthetic protocols for C–C bond forming reactions on nonplanar porphyrins are underdeveloped. The development of C–C…”
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Investigating the brain's neurochemical profile at midlife in relation to dementia risk factors
Published in Brain communications (2024)“…Changes in the brain's physiology in Alzheimer's disease are thought to occur early in the disease's trajectory. In this study our aim was to investigate the…”
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Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non‐demented individuals
Published in Alzheimer's & dementia (01-09-2024)“…INTRODUCTION Unraveling how Alzheimer's disease (AD) genetic risk is related to neuropathological heterogeneity, and whether this occurs through specific…”
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Connexins in neurons and glia: targets for intervention in disease and injury
Published in Neural regeneration research (01-07-2015)“…Both neurons and glia throughout the central nervous system are organized into networks by gap junctions. Among glia, gap junctions facilitate metabolic…”
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Platelet Tau Protein as a Potential Peripheral Biomarker in Alzheimer's Disease: An Explorative Study
Published in Current Alzheimer research (01-01-2018)“…Cerebrospinal fluid (CSF) measures of tau and amyloid proteins have now been largely accepted to be a diagnostic tool to aid the clinical diagnosis of…”
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Patterns of cerebellar volume loss in dementia with Lewy bodies and Alzheimer׳s disease: A VBM-DARTEL study
Published in Psychiatry research. Neuroimaging (30-09-2014)“…Abstract Evidence suggests that the cerebellum contributes to cognition as well as motor function. We investigated cerebellar grey matter (GM) and white matter…”
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Electrical Performance and Reliability Characterization of a SiC MOSFET Power Module With Embedded Decoupling Capacitors
Published in IEEE transactions on power electronics (01-12-2018)“…Integration of decoupling capacitors into silicon carbide (SiC) metal oxide semiconductor field effect transistor ( mosfet ) modules is an advanced solution to…”
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Convergence in Environmental Reporting: Assessing the Carbon Disclosure Project
Published in Business strategy and the environment (01-07-2013)“…ABSTRACT We perform content analysis on Carbon Disclosure Project (CDP) responses from 2003 to 2010, focusing on the extent to which firms account for indirect…”
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Analysts' Interim Earnings Forecasts: Evidence on the Forecasting Process
Published in Journal of accounting research (01-04-1994)“…The question of whether the expectation formation process underlying analyst forecasts is adaptive, or whether these forecasts are influenced by…”
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Changes in white matter as determinant of global functional decline in older independent outpatients: three year follow-up of LADIS (leukoaraiosis and disability) study cohort
Published in BMJ (01-08-2009)“…Objective To assess the impairment in daily living activities in older people with age related changes in white matter according to the severity of these…”
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Stable Isotopes and Planktonic Trophic Structure in Arctic Lakes
Published in Ecology (Durham) (01-04-1992)“…Actual food-web structure or function is difficult to determine based on visual observation, gut analyses, or the feeding interactions expected from a given…”
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Ensuring that COVID-19 research is inclusive: guidance from the NIHR INCLUDE project
Published in BMJ open (05-11-2020)“…ObjectiveTo provide guidance to researchers, funders, regulators and study delivery teams to ensure that research on COVID-19 is inclusive, particularly of…”
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Union Jack: Amnesia and the Law in Daniel Defoe's "Colonel Jack"
Published in Eighteenth-century studies (01-10-1998)“…O'Brien discusses Daniel Defoe's "The History and Remarkable Life of the Truly Honourable Col. Jacque, Commonly Call'd Col. Jack." The eponymous hero in the…”
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Pain and distress in advanced dementia: Choosing the right tools for the job
Published in Palliative medicine (01-10-2012)“…Objective: There is a concern that pain is under-recognized in dementia. However, there may be other causes of distress. We wished to evaluate the utility of a…”
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Is This Time Different? Trend-Following and Financial Crises
Published in The journal of alternative investments (01-09-2014)“…Following large positive returns in 2008, CTAs received increased attention and allocations from institutional investors. Subsequent performance has been below…”
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