Search Results - "O’Tuathaigh, Colm M."
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Medical students' empathy and attitudes towards professionalism: Relationship with personality, specialty preference and medical programme
Published in PloS one (02-05-2019)“…Existing research has suggested that self-reported empathy in medical students is moderated by personality traits and diverse demographic and educational…”
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Age-related hearing loss and provider-patient communication across primary and secondary care settings: a cross-sectional study
Published in Age and ageing (24-08-2020)“…Abstract Background The prevalence of age-related hearing loss (ARHL) increases with age. Older adults are amongst the most dependent users of healthcare and…”
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Developmental Genes and Regulatory Proteins, Domains of Cognitive Impairment in Schizophrenia Spectrum Psychosis and Implications for Antipsychotic Drug Discovery: The Example of Dysbindin-1 Isoforms and Beyond
Published in Frontiers in pharmacology (29-01-2020)“…Alongside positive and negative symptomatology, deficits in working memory, attention, selective learning processes, and executive function have been widely…”
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Dysregulation of Specialized Delay/Interference-Dependent Working Memory Following Loss of Dysbindin-1A in Schizophrenia-Related Phenotypes
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2017)“…Dysbindin-1, a protein that regulates aspects of early and late brain development, has been implicated in the pathobiology of schizophrenia. As the functional…”
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Genetic dissection of the psychotomimetic effects of cannabinoid exposure
Published in Progress in neuro-psychopharmacology & biological psychiatry (03-07-2014)“…Cannabis use is an established risk factor for the development of schizophrenia and related psychotic disorders. Factors that may mediate susceptibility to the…”
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Impact of hearing loss on clinical interactions between older adults and health professionals: a systematic review
Published in European geriatric medicine (01-12-2020)“…Key summary points Objectives This review quantified the extent to which hearing loss is cited and/or accounted for in studies of older adult interactions with…”
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Medical student perceptions of radiology use in anatomy teaching
Published in Anatomical sciences education (01-11-2015)“…The use of radiology in the teaching of anatomy to medical students is gaining in popularity; however, there is wide variation in how and when radiology is…”
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Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous ‘knockout’ of the schizophrenia risk gene neuregulin-1
Published in Progress in neuro-psychopharmacology & biological psychiatry (15-02-2008)“…Clinical genetic studies have implicated neuregulin-1 [NRG1] as a leading susceptibility gene for schizophrenia. NRG1 is known to play a significant role in…”
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Association between learning style preferences and anatomy assessment outcomes in graduate-entry and undergraduate medical students
Published in Anatomical sciences education (08-07-2016)“…An improved understanding of the relationship between anatomy learning performance and approaches to learning can lead to the development of a more tailored…”
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Trace but Not Delay Fear Conditioning Requires Attention and the Anterior Cingulate Cortex
Published in Proceedings of the National Academy of Sciences - PNAS (28-10-2003)“…Higher cognitive functions such as attention have been difficult to model in genetically tractable organisms. In humans, attention-distracting stimuli…”
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Chronic Adolescent Exposure to Delta-9-Tetrahydrocannabinol in COMT Mutant Mice: Impact on Indices of Dopaminergic, Endocannabinoid and GABAergic Pathways
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2012)“…Cannabis use confers a two-fold increase in risk for psychosis, with adolescent use conferring an even greater risk. A high-low activity polymorphism in…”
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Cannabis Use, Schizotypy and Kamin Blocking Performance
Published in Frontiers in psychiatry (23-11-2021)“…Cannabis use has been associated with increased risk for a first episode of psychosis and inappropriate assignment of salience to extraneous stimuli has been…”
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Susceptibility genes for schizophrenia: Characterisation of mutant mouse models at the level of phenotypic behaviour
Published in Neuroscience and biobehavioral reviews (2007)“…A wealth of evidence indicates that schizophrenia is heritable. However, the genetic mechanisms involved are poorly understood. Furthermore, it may be that…”
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Genetically modified mice related to schizophrenia and other psychoses: Seeking phenotypic insights into the pathobiology and treatment of negative symptoms
Published in European neuropsychopharmacology (01-05-2014)“…Abstract Modelling negative symptoms in any animal model, particularly in mice mutant for genes related to schizophrenia, is complicated by the absence of the…”
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Mutant mouse models: genotype-phenotype relationships to negative symptoms in schizophrenia
Published in Schizophrenia bulletin (01-03-2010)“…Negative symptoms encompass diminution in emotional expression and motivation, some of which relate to human attributes that may not be accessible readily in…”
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Advancing a functional genomics for schizophrenia: Psychopathological and cognitive phenotypes in mutants with gene disruption
Published in Brain research bulletin (30-09-2010)“…Abstract Schizophrenia is a complex, heritable psychotic disorder in which numerous genes and environmental adversities appear to interact in determining…”
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Medical student empathy and breaking bad news communication in a simulated consultation
Published in Patient education and counseling (01-05-2022)“…•We describe psychological factors influencing breaking bad news communication.•Aspects of self-reported empathy predicted communication competence in medical…”
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Mutant mouse models: phenotypic relationships to domains of psychopathology and pathobiology in schizophrenia
Published in Schizophrenia bulletin (01-03-2010)“…The present series of review articles seeks to elaborate how current findings in mutant mice may inform on the relationship between candidate genes and…”
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Selection of student-selected component [SSCs] modules across the medical undergraduate curriculum: Relationship with motivational factors
Published in Medical teacher (01-10-2012)“…Student-selected components (SSCs) encourage the following within the undergraduate medical curriculum: greater exploration of core curriculum topics;…”
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Modelling the neuromotor abnormalities of psychotic illness: Putative mechanisms and systems dysfunction
Published in Schizophrenia research (01-10-2018)“…Limitations in access to antipsychotic-naïve patients and in the incisiveness of studies that can be conducted on them, together with the inevitability of…”
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