Search Results - "O’Sullivan, J."

Telomeres: protecting chromosomes against genome instability by Karlseder, Jan, O'Sullivan, Roderick J

“…Key Points Telomeric proteins control telomere length and telomere integrity. The six bona fide telomeric binding proteins form shelterin, a complex that…”
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Enhanced wave overtopping simulation at vertical breakwaters using machine learning algorithms by Habib, M. A., O’Sullivan, J. J., Abolfathi, S., Salauddin, M.

“…Accurate prediction of wave overtopping at sea defences remains central to the protection of lives, livelihoods, and infrastructural assets in coastal zones…”
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The Endosomal Recycling Pathway-At the Crossroads of the Cell by O'Sullivan, Mary J, Lindsay, Andrew J

“…The endosomal recycling pathway lies at the heart of the membrane trafficking machinery in the cell. It plays a central role in determining the composition of…”
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New insights in the probability distributions of wave-by-wave overtopping volumes at vertical breakwaters by Salauddin, M., O’Sullivan, J. J., Abolfathi, S., Peng, Z., Dong, S., Pearson, J. M.

“…Advances in the development of prediction tools for wave overtopping allow now for overtopping volumes to be estimated with good accuracy, with the combined…”
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Gold nanoparticles as novel agents for cancer therapy by JAIN, S, HIRST, D. G, O'SULLIVAN, J. M

“…Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and…”
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Povidone iodine development by O’Sullivan, J.

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Parents’ experiences of infant and young child feeding during the COVID-19 pandemic in Ireland by O’Sullivan, Elizabeth J, Kennedy, Aileen

“…The WHO has urged member states to develop preparedness plans for infant and young child feeding (IYCF) during emergencies. Ireland has no such plan. We aimed…”
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Understanding the impact of SNPs associated with autism spectrum disorder on biological pathways in the human fetal and adult cortex by Golovina, E., Fadason, T., Lints, T. J., Walker, C., Vickers, M. H., O’Sullivan, J. M.

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by significant and complex genetic etiology. GWAS studies have identified genetic…”
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Reinjection in geothermal fields: A review of worldwide experience by Kaya, Eylem, Zarrouk, Sadiq J., O'Sullivan, Michael J.

“…The worldwide experience of reinjection in geothermal fields is reviewed. Information from 91 electric-power producing geothermal fields shows that: a…”
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An exploratory analysis of alkaline phosphatase, lactate dehydrogenase, and prostate-specific antigen dynamics in the phase 3 ALSYMPCA trial with radium-223 by Sartor, O., Coleman, R.E., Nilsson, S., Heinrich, D., Helle, S.I., O’Sullivan, J.M., Vogelzang, N.J., Bruland, Ø., Kobina, S., Wilhelm, S., Xu, L., Shan, M., Kattan, M.W., Parker, C.

“…Baseline clinical variables are prognostic for overall survival (OS) in patients with castration-resistant prostate cancer (CRPC). Their prognostic and…”
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In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition by Mitchel, Jennifer A., Das, Amit, O’Sullivan, Michael J., Stancil, Ian T., DeCamp, Stephen J., Koehler, Stephan, Ocaña, Oscar H., Butler, James P., Fredberg, Jeffrey J., Nieto, M. Angela, Bi, Dapeng, Park, Jin-Ah

“…The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each comprises a gateway to cellular migration, plasticity and remodeling,…”
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Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres by Karlseder, Jan, Kubicek, Stefan, Schreiber, Stuart L, O'Sullivan, Roderick J

“…Telomere shortening, senescence and aging are connected, but how the signal at shortening telomeres is transmitted to the cell more globally is unclear. H3 and…”
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Genome rearrangements associated with aberrant telomere maintenance by Bhargava, Ragini, Fischer, Matthias, O’Sullivan, Roderick J

“…There is unequivocal evidence that telomeres are crucial for cellular homeostasis and that telomere dysfunction can elicit genome instability and potentially…”
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RAS-pathway mutations are common in patients with ruxolitinib refractory/intolerant myelofibrosis: molecular analysis of the PAC203 cohort by O’Sullivan, J. M., Taylor, J., Gerds, A., Buckley, S., Harrison, C. N., Oh, S., List, A. F., Howard, K., Dreau, H., Hamblin, A., Mead, A. J.

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Discordant High-Gradient Aortic Stenosis: Trust the Gradient by O’Sullivan, Crochan J., O’Sullivan, David

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Medical doctors’ knowledge of dental trauma management: A review by Yeng, Thai, O’Sullivan, Anthony J., Shulruf, Boaz

“…Education in dental trauma is extremely important to promote knowledge on the assessment and management of a traumatized tooth. Medical doctors are normally…”
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Effect of 3D printing on the structure and textural properties of processed cheese by Le Tohic, Camille, O'Sullivan, Jonathan J., Drapala, Kamil P., Chartrin, Valentin, Chan, Tony, Morrison, Alan P., Kerry, Joseph P., Kelly, Alan L.

“…Three-dimensional (3D) printing is a process whereby complex three-dimensional objects are generated. In this study, 3D printing was investigated for food…”
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Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1 by O'Sullivan, Roderick J, Arnoult, Nausica, Lackner, Daniel H, Oganesian, Liana, Haggblom, Candy, Corpet, Armelle, Almouzni, Genevieve, Karlseder, Jan

“…Some cancer cells lacking telomerase activity extend their telomeres via an alternative, recombination-based mechanism, termed ALT. A new study shows that…”
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Myocardial Damage and Severe Aortic Stenosis: Looking Beyond the Left Ventricular Ejection Fraction by O’Sullivan, Cróchán J.

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Dysregulated bioenergetics: a key regulator of joint inflammation by Biniecka, M, Canavan, M, McGarry, T, Gao, W, McCormick, J, Cregan, S, Gallagher, L, Smith, T, Phelan, J J, Ryan, J, O'Sullivan, J, Ng, C T, Veale, D J, Fearon, U

“…This study examines the relationship between synovial hypoxia and cellular bioenergetics with synovial inflammation. Primary rheumatoid arthritis synovial…”
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