Search Results - "O’Sullivan, Hazel"

FOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathways by Kelleher, Fergal C, O'Sullivan, Hazel

“…FOXM1 is a pro-proliferative transcription factor that promotes cell cycle progression at the G1-S, and G2-M transitions. It is activated by phosphorylation…”
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Characterization of sebaceous and non-sebaceous cutaneous manifestations in patients with lynch syndrome: a systematic review by Aziz, Shahram, O’Sullivan, Hazel, Heelan, Kara, Alam, Afrina, McVeigh, Terri P.

“…A subset of patients with Lynch Syndrome demonstrates cutaneous manifestations of the disorder. Characterization of these Lynch-related skin lesions could help…”
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Optimising oncology drug expenditure in Ireland by Kieran, Ruth, Hennessy, Maeve, Coakley, Kate, O’Sullivan, Hazel, Cronin, Tim, Lynch, Daire, Mulroe, Eibhlin, Cooke, Katie, Collins, Dearbhaile, O’Reilly, Seamus

“…A combination of improvements in patient survival, increasing treatment duration, and the development of more expensive agents has led to a doubling of…”
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Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer by Aktas, Burak Y, Taban, Hakan, Aksoy, Sercan, O’Sullivan, Hazel, Collins, Dearbhaile, O’Reilly, Seamus, Altundag, Kadri, Schmid, Peter, Chui, Stephen Y, Emens, Leisha A

“…To the Editor: In the IMpassion130 trial, Schmid et al. (Nov. 29 issue) 1 found that combination therapy with atezolizumab plus nanoparticle albumin-bound…”
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Salvage Therapy With Selpercatinib for RET-Rearranged NSCLC With Pralsetinib-Related Pneumonitis and Leptomeningeal Disease: A Case Report by d'Arienzo, Paolo Davide, Cunningham, Niamh, O’Sullivan, Hazel, Grieco, Charlotte, Patel, Virjen, Popat, Sanjay

“…Selpercatinib and pralsetinib are RET inhibitors with substantial activity in advanced RET-rearranged NSCLC. We present a case of pralsetinib-related…”
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Oxford and the Savannah: Can the Hippo Provide an Explanation for Peto's Paradox? by KELLEHER, Fergal C, O'SULLIVAN, Hazel

“…Peto's paradox is the counterintuitive finding that increasing body mass and thereby cell number does not correlate with an increase in cancer incidence across…”
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Therapeutic Potential for FGFR Inhibitors in SOX9-FGFR2 Coexpressing Pancreatic Cancer by OʼSullivan, Hazel, Kelleher, Fergal C, Lavelle, Máire, McGovern, Brianan, Murphy, Jean, Swan, Niall, McDermott, Ray

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Effect on Overall Survival of Locoregional Treatment in a Cohort of De Novo Metastatic Prostate Cancer Patients: A Single Institution Retrospective Analysis From the Royal Marsden Hospital by Bianchini, Diletta, Lorente, David, Rescigno, Pasquale, Zafeiriou, Zafeiris, Psychopaida, Elena, O'Sullivan, Hazel, Alaras, Mervyn, Kolinsky, Michael, Sumanasuriya, Semini, Sousa Fontes, Mariane, Mateo, Joaquin, Perez Lopez, Raquel, Tunariu, Nina, Fotiadis, Nikolaos, Kumar, Pardeep, Tree, Alison, Van As, Nicholas, Khoo, Vincent, Parker, Chris, Eeles, Rosalind, Thompson, Alan, Dearnaley, David, de Bono, Johann S.

“…We retrospectively evaluated the effect of locoregional treatment (LRT) on overall survival (OS) in 300 metastatic at diagnosis (M1) prostate cancer patients…”
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Minimal Residual Disease Monitoring in Radically Treated Non-Small Cell Lung Cancer: Challenges and Future Directions by O'Sullivan, Hazel M, Feber, Andrew, Popat, Sanjay

“…Circulating tumor DNA (ctDNA) analysis can identify patients with residual disease before it is clinically or radiologically evident. Minimal residual disease…”
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Atezolizumab in patients with advanced non-small-cell lung cancer who are platinum-doublet ineligible by O'Sullivan, Hazel, Popat, Sanjay

“…Before these inhibitors, 5-year survival rates were 0% for stage IVB disease1 but now approach 20% in those without substantial comorbidities and Eastern…”
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Updates in Management of Malignant Pleural Mesothelioma by John, Alexius, O’Sullivan, Hazel, Popat, Sanjay

“…Opinion statement Malignant pleural mesothelioma (MPM) is an aggressive asbestos-associated thoracic malignancy that is usually incurable. As demonstrated in…”
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Expert by experience involvement in mental health nursing education: The co‐production of standards between Experts by Experience and academics in mental health nursing by Horgan, Aine, Manning, Fionnuala, Donovan, Moira O., Doody, Rory, Savage, Eileen, Bradley, Stephen K., Dorrity, Claire, O’Sullivan, Hazel, Goodwin, John, Greaney, Sonya, Biering, Pall, Bjornsson, Einar, Bocking, Julia, Russell, Siobhan, MacGabhann, Liam, Griffin, Martha, Vaart, Kornelis Jan, Allon, Jerry, Granerud, Arild, Hals, Elisabeth, Pulli, Jarmo, Vatula, Annaliina, Ellilä, Heikki, Lahti, Mari, Happell, Brenda

“…Accessible summary What is known on the subject Expert by Experience (EBE) involvement in mental health nursing education has demonstrated benefits, including…”
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‘Meet Me Where I Am’: Mental health service users’ perspectives on the desirable qualities of a mental health nurse by Horgan, Aine, O Donovan, Moira, Manning, Fionnuala, Doody, Rory, Savage, Eileen, Dorrity, Claire, O’Sullivan, Hazel, Goodwin, John, Greaney, Sonya, Biering, Pall, Bjornsson, Einar, Bocking, Julia, Russell, Siobhan, Griffin, Martha, MacGabhann, Liam, Vaart, Kornelis Jan, Allon, Jerry, Granerud, Arild, Hals, Elisabeth, Pulli, Jarmo, Vatula, Annaliina, Ellilä, Heikki, Lahti, Mari, Happell, Brenda

“…Nurses play a central role in the delivery of quality mental health services. Desired qualities of a mental health nurse, in particular therapeutic…”
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The role of circulating tumour DNA in guiding cancer treatment and future applications

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Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer by O'Sullivan, Hazel, Collins, Dearbhaile, O'Reilly, Seamus

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Improving Service User Involvement in Mental Health Nursing Education: Suggestions from Those with Lived Experience by Horgan, Aine, Donovan, Moira O., Doody, Rory, Savage, Eileen, Dorrity, Claire, O'Sullivan, Hazel, Goodwin, John, Greaney, Sonya, Biering, Pall, Bjornsson, Einar, Bocking, Julia, MacGabhann, Liam, Russell, Siobhan, Griffin, Martha, Jan van der Vaart, Kornelis, Allon, Jerry, Granerud, Arild, Hals, Elisabeth, Pulli, Jarmo, Vatula, Annaliina, Ellilä, Heikki, Lahti, Mari, Happell, Brenda

“…Service user involvement in mental health nursing education is increasing and a developing evidence base is demonstrating more positive attitudes towards…”
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BRAF inhibitor treatment of melanoma causing colonic polyps:An alternative hypothesis by Kelleher, Fergal C, Callaghan, Grainne, Gallagher, Catriona, O’Sullivan, Hazel

“…Colonic polyps may arise from BRAF inhibitor treatment of melanoma, possibly due paradoxical activation of the mitogen-activated protein(MAP)-kinase pathway…”
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“The third wing of the plane”: Fathers' perceptions of their role in the treatment process for daughters with eating disorders by O'Sullivan, Hazel, Goodwin, John, O'Malley, Maria, Happell, Brenda, O'Donovan, Aine

“…Eating disorders are complex mental health conditions exacerbated by high mortality rates. International and national guidelines recommend family involvement…”
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Inadequacy of PCR genotyping in advanced non-small cell lung cancer: EGFR L747_A755delinsSS exon 19 deletion is not detected by the real-time PCR Idylla™ EGFR mutation test but is detected by ctDNA next generation sequencing and responds to osimertinib by O'Sullivan, Hazel, d'Arienzo, Paolo D., Yousaf, Nadia, Cui, Wanyuan, Popat, Sanjay

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Response to letter entitled: Re: 'Inadequacy of PCR genotyping in advanced non-small cell lung cancer: EGFR L747_A755delinsSS exon 19 deletion is not detected by the real-time PCR IdyllaTM EGFR mutation test but is detected by ctDNA NGS and responds to osimertinib': Not looking back by O'Sullivan, Hazel, D'Arienzo, Paolo D, Yousaf, Nadia, Cui, Wanyuan, Popat, Sanjay

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