Search Results - "O’Reilly, Michael"

11-oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome by O’Reilly, Michael W, Kempegowda, Punith, Jenkinson, Carl, Taylor, Angela E, Quanson, Jonathan L, Storbeck, Karl-Heinz, Arlt, Wiebke

“…Context:Androgen excess is a defining feature of polycystic ovary syndrome (PCOS) but the exact origin of hyperandrogenemia remains a matter of debate. Recent…”
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Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database by Kumarendran, Balachandran, O'Reilly, Michael W, Manolopoulos, Konstantinos N, Toulis, Konstantinos A, Gokhale, Krishna M, Sitch, Alice J, Wijeyaratne, Chandrika N, Coomarasamy, Arri, Arlt, Wiebke, Nirantharakumar, Krishnarajah

“…Androgen excess is a defining feature of polycystic ovary syndrome (PCOS), which affects 10% of women and represents a lifelong metabolic disorder, with…”
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Increased COVID-19 infections in women with polycystic ovary syndrome: a population-based study by Subramanian, Anuradhaa, Anand, Astha, Adderley, Nicola J, Okoth, Kelvin, Toulis, Konstantinos A, Gokhale, Krishna, Sainsbury, Christopher, O’Reilly, Michael W, Arlt, Wiebke, Nirantharakumar, Krishnarajah

“…Objective Several recent observational studies have linked metabolic comorbidities to an increased risk from COVID-19. Here we investigated whether women with…”
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Mortality among older adults with osteoporotic vertebral fracture by Gold, Laura S., Suri, Pradeep, O’Reilly, Michael K., Kallmes, David F., Heagerty, Patrick J., Jarvik, Jeffrey G.

“…Summary We evaluated whether older adults who received kyphoplasty had reduced risk of mortality compared to those who did not. In unmatched analyses, those…”
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Outcome of Nonfunctioning Pituitary Adenomas That Regrow After Primary Treatment: A Study From Two Large UK Centers by Tampourlou, Metaxia, Ntali, Georgia, Ahmed, Shahzada, Arlt, Wiebke, Ayuk, John, Byrne, James V, Chavda, Swarupsinh, Cudlip, Simon, Gittoes, Neil, Grossman, Ashley, Mitchell, Rosalind, O’Reilly, Michael W, Paluzzi, Alessandro, Toogood, Andrew, Wass, John A H, Karavitaki, Niki

“…Despite the major risk of regrowth of clinically nonfunctioning pituitary adenomas (CNFAs) after primary treatment, systematic data on the probability of…”
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Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle variation by Schiffer, Lina, Kempegowda, Punith, Sitch, Alice J, Adaway, Joanne E, Shaheen, Fozia, Ebbehoj, Andreas, Singh, Sumitabh, McTaggart, Malcom P, O'Reilly, Michael W, Prete, Alessandro, Hawley, James M, Keevil, Brian G, Bancos, Irina, Taylor, Angela E, Arlt, Wiebke

“…11-oxygenated androgens significantly contribute to the circulating androgen pool. Understanding the physiological variation of 11-oxygenated androgens and…”
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Understanding androgen action in adipose tissue by O'Reilly, Michael W, House, Philip J, Tomlinson, Jeremy W

“…Androgens play an important role in regulation of body fat distribution in humans. They exert direct effects on adipocyte differentiation in a depot-specific…”
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Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling by Zhao, Lan, Yee, Min, O'Reilly, Michael A

“…Alveolar epithelial type II (ATII) cells are essential for maintaining normal lung homeostasis because they produce surfactant, express innate immune proteins,…”
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Natural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess: A Systematic Review and Meta-analysis by Elhassan, Yasir S, Alahdab, Fares, Prete, Alessandro, Delivanis, Danae A, Khanna, Aakanksha, Prokop, Larry, Murad, Mohammad H, O'Reilly, Michael W, Arlt, Wiebke, Bancos, Irina

“…Adrenal incidentalomas are mostly benign nonfunctioning adrenal tumors (NFATs) or adenomas causing mild autonomous cortisol excess (MACE), but their natural…”
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Approach to androgen excess in women: Clinical and biochemical insights by Cussen, Leanne, McDonnell, Tara, Bennett, Gillian, Thompson, Christopher J., Sherlock, Mark, O'Reilly, Michael W.

“…Androgen excess in women typically presents clinically with hirsutism, acne or androgenic alopecia. In the vast majority of cases, the underlying aetiology is…”
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Influence of Solvating Plasticizer on Ion Conduction of Polysiloxane Single-Ion Conductors by Choi, U Hyeok, Liang, Siwei, O’Reilly, Michael V, Winey, Karen I, Runt, James, Colby, Ralph H

“…Lithium ion conduction is investigated for a polysiloxane-based single-ion conductor containing weak-binding borates and cyclic carbonate side chains,…”
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Increased risk of obstructive sleep apnoea in women with polycystic ovary syndrome: a population-based cohort study by Kumarendran, Balachandran, Sumilo, Dana, O’Reilly, Michael W, Toulis, Konstantinos A, Gokhale, Krishna M, Wijeyaratne, Chandrika N, Coomarasamy, Arri, Arlt, Wiebke, Tahrani, Abd A, Nirantharakumar, Krishnarajah

“…Objective Obesity is very common in patients with obstructive sleep apnoea (OSA) and polycystic ovary syndrome (PCOS). Longitudinal studies assessing OSA risk…”
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Editorial for Clinical Endocrinology Special Issue on Congenital Adrenal Hyperplasia by O'Reilly, Michael W., Aled Rees, D.

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Giving New Identities to Alveolar Epithelial Type I Cells by O'Reilly, Michael A

“…AT2 cells are perhaps best known for their expression of surfactant protein C (SFTPC). Because SFTPC is expressed solely in the lung by AT2 cells, it was used…”
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Out of Tune: Fibroblasts Turn Fibrotic When They Lack a FENDRR by Woeller, Collynn F, O'Reilly, Michael A

“…Idiopathic pulmonary fibrosis (IPF) is a progressive and incurable disease. Patients have a mean life expectancy of 3-5 years after diagnosis. IPF is…”
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Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery by Chang, Joe Y, Mehran, Reza J, Feng, Lei, Verma, Vivek, Liao, Zhongxing, Welsh, James W, Lin, Steven H, O'Reilly, Michael S, Jeter, Melenda D, Balter, Peter A, McRae, Stephen E, Berry, Donald, Heymach, John V, Roth, Jack A, Antonoff, Mara, Hofstetter, Wayne, Rajaram, Ravi, Rice, David, Sepesi, Boris, Swisher, Stephen, Vaporciyan, Ara, Walsh, Garrett, DeGraaf, Craig, Correa, Arlene, Chen, Aileen, Gandhi, Saumil, Komaki, Ritsuko, Lee, Percy, Nguyen, Quynh-Nhu, Ning, Matthew, Gao, Song, Pollard-Larkin, Julianne, Nitsch, Paige, Sadagopan, Ramaswamy, Wang, Xiaochun

“…A previous pooled analysis of the STARS and ROSEL trials showed higher survival after stereotactic ablative radiotherapy (SABR) than with surgery for operable…”
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Early Neonatal Oxygen Exposure Predicts Pulmonary Morbidity and Functional Deficits at 1 Year by Dylag, Andrew M., Kopin, Hannah G., O'Reilly, Michael A., Wang, Hongyue, Davis, Stephanie D., Ren, Clement L., Pryhuber, Gloria S.

“…To evaluate the predictive value of cumulative oxygen exposure thresholds over the first 2 postnatal weeks, linking them to bronchopulmonary dysplasia (BPD)…”
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Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia by McGrath-Morrow, Sharon A, Ndeh, Roland, Collaco, Joseph M, Rothblum-Oviatt, Cynthia, Wright, Jennifer, O'Reilly, Michael A, Singer, Benjamin D, Lederman, Howard M

“…Classic ataxia telangiectasia (A-T) is an autosomal recessive disease characterized by early onset ataxia, immune deficiency, sino-pulmonary disease,…”
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Standardising the biochemical confirmation of adult male hypogonadism; a joint position statement by the Society for Endocrinology and Association of Clinical Biochemistry and Laboratory Medicine by Jayasena, Channa N, de Silva, Nipun Lakshitha, O'Reilly, Michael W, MacKenzie, Finlay, Marrington, Rachel, Jones, Hugh, Livingston, Mark, Downie, Paul, Hackett, Geoff, Ramachandran, Sud, Tomlinson, Jeremy, David, Janine, Boot, Christopher, Patel, Mayur, Tarling, Julie, Wu, Fredrick, Quinton, Richard

“…Inter-assay variation between different immunoassays and different mass spectrometry methods hampers the biochemical confirmation of male hypogonadism…”
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The role for long-term use of dehydroepiandrosterone in adrenal insufficiency by Bennett, Gillian, Cussen, Leanne, O’Reilly, Michael W.

“…Dehydroepiandrosterone (DHEA) is an androgen produced by the zona reticularis of the adrenal gland. Patients with adrenal insufficiency will have a deficiency…”
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