Search Results - "O’Neill, S.C."

What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis? by Eisner, D.A, Kashimura, T, O'Neill, S.C, Venetucci, L.A, Trafford, A.W

“…Abstract In this article we review the role of the Ryanodine Receptor (RyR) in cardiac inotropy and arrhythmogenesis. Most of the calcium that activates…”
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Young smokers' interpretations of the estimated lung cancer risk associated with a common genetic variant of low penetrance by Sanderson, S C, McBride, C M, O'Neill, S C, Docherty, S, Shepperd, J, Lipkus, I M

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The control of Ca release from the cardiac sarcoplasmic reticulum : regulation versus autoregulation by EISNER, D. A, TRAFFORD, A. W, DIAZ, M. E, OVEREND, C. L, O'NEILL, S. C

“…This review discusses the mechanism and regulation of Ca release from the cardiac sarcoplasmic reticulum. Ca is released through the Ca release channel or…”
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Measurement of sarcoplasmic reticulum Ca2+ content and sarcolemmal Ca2+ fluxes in isolated rat ventricular myocytes during spontaneous Ca2+ release by Díaz, M E, Trafford, A W, O'Neill, S C, Eisner, D A

“…1. Intracellular calcium concentration ([Ca2+]i) and Na(+)-Ca2+ exchange currents were measured in calcium-overloaded voltage-clamped rat ventricular myocytes…”
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Caffeine inhibits the agonist-evoked cytosolic Ca2+ signal in mouse pancreatic acinar cells by blocking inositol trisphosphate production by TOESCU, E. C, O'NEILL, S. C, PETERSEN, O. H, EISNER, D. A

“…The inhibitory effects of caffeine on receptor-activated cytosolic Ca2+ signal generation in isolated mouse pancreatic acinar cells were investigated. Using…”
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The effect of 2,5-di-(tert-butyl)-1,4-benzohydroquinone (TBQ) on intracellular Ca2+ handling in rat ventricular myocytes by Miller, L, Greensmith, D.J, Sankaranarayanan, R, O’Neill, S.C, Eisner, D.A

“…Graphical abstract…”
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Reducing Ryanodine Receptor Open Probability as a Means to Abolish Spontaneous Ca2+ Release and Increase Ca2+ Transient Amplitude in Adult Ventricular Myocytes by Venetucci, L A, Trafford, A W, Díaz, M E, O’Neill, S C, Eisner, D A

“…The aim of this work was to investigate whether it is possible to remove arrhythmogenic Ca release from the sarcoplasmic reticulum that occurs in calcium…”
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Depressed Ryanodine Receptor Activity Increases Variability and Duration of the Systolic Ca2+ Transient in Rat Ventricular Myocytes by Díaz, M E, Eisner, D A, O’Neill, S C

“…ABSTRACT—Sarcoplasmic reticulum (SR) Ca release, through the ryanodine receptor (RyR), is essential for the systolic Ca transient and thus the cardiac…”
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The control of sarcoplasmic reticulum Ca content in cardiac muscle by Díaz, M.E., Graham, H.K., O’Neill, S.C., Trafford, A.W., Eisner, D.A.

“…Most of the calcium that activates contraction in the heart comes from the sarcoplasmic reticulum (SR) and it is therefore essential to control the SR Ca…”
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Comparison of the effects of caffeine and other methylxanthines on [Ca2+]i in rat ventricular myocytes by Donoso, P., O'Neill, S.C., Dilly, K.W., Negretti, N., Eisner, D.A.

“…1 The effects of caffeine and other methylxanthines were investigated on intracellular calcium concentration ([Ca2+]i) and contraction in rat isolated…”
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Does the adenosine A2A receptor stimulate the ryanodine receptor? by Venetucci, L., O'Neill, S.C., Eisner, D.A.

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The effect of 2,5-di-(tert-butyl)-1,4-benzohydroquinone (TBQ) on intracellular Ca 2+ handling in rat ventricular myocytes by Miller, L., Greensmith, D.J., Sankaranarayanan, R., O’Neill, S.C., Eisner, D.A.

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Measurement of sarcoplasmic reticulum Ca 2+ content and sarcolemmal Ca 2+ fluxes in isolated rat ventricular myocytes during spontaneous Ca 2+ release by Díaz, M.E., Trafford, A.W., O'Neill, S.C., Eisner, D.A.

“…Intracellular calcium concentration ([Ca 2+ ] i ) and Na + –Ca 2+ exchange currents were measured in calcium‐overloaded voltage‐clamped rat ventricular…”
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What can interest tell us about uptake of genetic testing? Intention and behavior amongst smokers related to patients with lung cancer by Sanderson, S C, O'Neill, S C, Bastian, L A, Bepler, G, McBride, C M

“…Much of the research examining psychosocial aspects of genetic testing has used hypothetical scenarios, based on the largely untested assumption that…”
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Na/K pump alpha subunit expression in rabbit ventricle and regional variations of intracellular sodium regulation by Lancaster, M K, Bennett, D L, Cook, S J, O'Neill, S C

“…We examined the isoform distribution and expression of the alpha subunit of the Na/K-ATPase in the left ventricular muscle of rabbit heart in order to…”
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Oxidation during metasomatism in ultramafic xenoliths from the Wesselton kimberlite, South Africa: implications for the survival of diamond by McCammon, C.A.

“…Garnets in xenoliths from the Wesselton kimberlite show significant zoning in major and trace elemnts. The garnets were studied using room temperature…”
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Reducing Ryanodine Receptor Open Probability as a Means to Abolish Spontaneous Ca 2+ Release and Increase Ca 2+ Transient Amplitude in Adult Ventricular Myocytes by Venetucci, L.A., Trafford, A.W., Díaz, M.E., O’Neill, S.C., Eisner, D.A.

“…The aim of this work was to investigate whether it is possible to remove arrhythmogenic Ca 2+ release from the sarcoplasmic reticulum that occurs in calcium…”
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An in situ Raman spectroscopic study of pressure induced dissociation of spinel NiCr2O4 by ZHONGWU WANG, SAXENA, S. K, LAZOR, Peter, O'NEILL, H. S. C

“…An in situ Raman spectroscopic study was conducted to investigate the pressure induced phase transformation of spinel NiCr2O4 to pressures of 57.1 GPa. Results…”
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High pressure Raman spectroscopic study of spinel MgCr2O4 by WANG, Z, O'NEILL, H. S. C, LAZOR, P, SAXENA, S. K

“…An in situ Raman spectroscopic study was conducted to investigate the pressure induced phase transformation of MgCr2O4 spinel up to pressures of 76.4 GPa…”
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On the Distribution and Variation of Radioactive Heat Producing Elements Within Meteorites, the Earth, and Planets by O’Neill, C., O’Neill, H. S. C., Jellinek, A. M.

“…The heat production budget of a planet exerts a first order control on its thermal evolution, tectonics, and likelihood for habitability. However, our…”
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