Search Results - "O’Neill, J"

Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem by Lawson, Melissa A. E., O’Neill, Ian J., Kujawska, Magdalena, Gowrinadh Javvadi, Sree, Wijeyesekera, Anisha, Flegg, Zak, Chalklen, Lisa, Hall, Lindsay J.

“…Diet-microbe interactions play an important role in modulating the early-life microbiota, with Bifidobacterium strains and species dominating the gut of…”
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Metabolic reprogramming in macrophages and dendritic cells in innate immunity by Kelly, Beth, O'Neill, Luke AJ

“…Activation of macrophages and dendritic cells （DCs） by pro-inflammatory stimuli causes them to undergo a metabolic switch towards glycolysis and away from…”
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Superficial layers of the medial entorhinal cortex replay independently of the hippocampus by O’Neill, J., Boccara, C.N., Stella, F., Schoenenberger, P., Csicsvari, J.

“…The hippocampus is thought to initiate systems-wide mnemonic processes through the reactivation of previously acquired spatial and episodic memory traces,…”
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Target protection as a key antibiotic resistance mechanism by Wilson, Daniel N., Hauryliuk, Vasili, Atkinson, Gemma C., O’Neill, Alex J.

“…Antibiotic resistance is mediated through several distinct mechanisms, most of which are relatively well understood and the clinical importance of which has…”
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Impaired glymphatic function and clearance of tau in an Alzheimer's disease model by Harrison, Ian F, Ismail, Ozama, Machhada, Asif, Colgan, Niall, Ohene, Yolanda, Nahavandi, Payam, Ahmed, Zeshan, Fisher, Alice, Meftah, Soraya, Murray, Tracey K, Ottersen, Ole P, Nagelhus, Erlend A, O'Neill, Michael J, Wells, Jack A, Lythgoe, Mark F

“…The glymphatic system, that is aquaporin 4 (AQP4) facilitated exchange of CSF with interstitial fluid (ISF), may provide a clearance pathway for protein…”
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The history of Toll-like receptors — redefining innate immunity by O'Neill, Luke A. J., Golenbock, Douglas, Bowie, Andrew G.

“…The past 15 years have seen a breakthrough in the field of innate immunity. In this Timeline article, the authors discuss the early events that led to the…”
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NLRP3 at the interface of metabolism and inflammation by Haneklaus, Moritz, O'Neill, Luke A. J.

“…Summary The discovery of the NLRP3 (NLR family, pyrin domain containing 3) inflammasome provided an important molecular mechanism in the induction of the…”
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Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections by Hurdle, Julian G, O'Neill, Alex J, Chopra, Ian, Lee, Richard E

“…Key Points When bacteria become quiescent (that is, slow growing or non-growing), they can avoid being killed by bactericidal antibiotics. This phenomenon…”
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The Immunomodulatory Potential of the Metabolite Itaconate by Hooftman, Alexander, O’Neill, Luke A.J.

“…The field of immunometabolism has demonstrated that metabolites can lead double lives as immunomodulators. Itaconate is perhaps the best example of such a…”
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Online misinformation about climate change by Treen, Kathie M. d'I., Williams, Hywel T. P., O'Neill, Saffron J.

“…Policymakers, scholars, and practitioners have all called attention to the issue of misinformation in the climate change debate. But what is climate change…”
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M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation by Morgan, Hugh P., O'Reilly, Francis J., Wear, Martin A., O'Neill, J. Robert, Fothergill-Gilmore, Linda A., Hupp, Ted, Walkinshaw, Malcolm D.

“…We show that the M2 isoform of pyruvate kinase (M2PYK) exists in equilibrium between monomers and tetramers regulated by allosteric binding of naturally…”
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Catalyst Design with Atomic Layer Deposition by O’Neill, Brandon J, Jackson, David H. K, Lee, Jechan, Canlas, Christian, Stair, Peter C, Marshall, Christopher L, Elam, Jeffrey W, Kuech, Thomas F, Dumesic, James A, Huber, George W

“…Atomic layer deposition (ALD) has emerged as an interesting tool for the atomically precise design and synthesis of catalytic materials. Herein, we discuss…”
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Big data techniques in auditing research and practice: Current trends and future opportunities by Gepp, Adrian, Linnenluecke, Martina K., O’Neill, Terrence J., Smith, Tom

“…[Display omitted] •Auditing is lagging behind in the use of valuable big data techniques.•There are many opportunities for greater use of big data techniques…”
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Anti-Cancer Properties of Theaflavins by O'Neill, Eric J, Termini, Deborah, Albano, Alexandria, Tsiani, Evangelia

“…Cancer is a disease characterized by aberrant proliferative and apoptotic signaling pathways, leading to uncontrolled proliferation of cancer cells combined…”
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ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection by Sharkey, Liam K R, Edwards, Thomas A, O'Neill, Alex J

“…Members of the ABC-F subfamily of ATP-binding cassette proteins mediate resistance to a broad array of clinically important antibiotic classes that target the…”
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Sex chromosome repeats tip the balance towards speciation by O'Neill, Michael J., O'Neill, Rachel J.

“…Because sex chromosomes, by definition, carry genes that determine sex, mutations that alter their structural and functional stability can have immediate…”
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Patient Age-Associated Mortality Risk Is Differentiated by BRAF V600E Status in Papillary Thyroid Cancer by Shen, Xiaopei, Zhu, Guangwu, Liu, Rengyun, Viola, David, Elisei, Rossella, Puxeddu, Efisio, Fugazzola, Laura, Colombo, Carla, Jarzab, Barbara, Czarniecka, Agnieszka, Lam, Alfred K, Mian, Caterina, Vianello, Federica, Yip, Linwah, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, O'Neill, Christine J, Sywak, Mark S, Clifton-Bligh, Roderick, Bendlova, Bela, Sýkorová, Vlasta, Xing, Mingzhao

“…Purpose For the past 65 years, patient age at diagnosis has been widely used as a major mortality risk factor in the risk stratification of papillary thyroid…”
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Climate change and visual imagery by O'Neill, Saffron J., Smith, Nicholas

“…Many actors—including scientists, journalists, artists, and campaigning organizations—create visualizations of climate change. In doing so, they evoke climate…”
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Staphylococcus aureus Biofilms Promote Horizontal Transfer of Antibiotic Resistance by Savage, Victoria J, Chopra, Ian, O'Neill, Alex J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Metabolism of inflammation limited by AMPK and pseudo-starvation by O'Neill, Luke A. J., Hardie, D. Grahame

“…Metabolic changes in cells that participate in inflammation, such as activated macrophages and T-helper 17 cells, include a shift towards enhanced glucose…”
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