Search Results - "O’FLANAGAN, D."

Irreversible electroporation augments checkpoint immunotherapy in prostate cancer and promotes tumor antigen-specific tissue-resident memory CD8+ T cells by Burbach, Brandon J., O’Flanagan, Stephen D., Shao, Qi, Young, Katharine M., Slaughter, Joseph R., Rollins, Meagan R., Street, Tami Jo L., Granger, Victoria E., Beura, Lalit. K., Azarin, Samira M., Ramadhyani, Satish, Forsyth, Bruce R., Bischof, John C., Shimizu, Yoji

“…Memory CD8+ T cells populate non-lymphoid tissues (NLTs) following pathogen infection, but little is known about the establishment of endogenous tumor-specific…”
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Cutting Edge: Nucleocapsid Vaccine Elicits Spike-Independent SARS-CoV-2 Protective Immunity by Matchett, William E, Joag, Vineet, Stolley, J Michael, Shepherd, Frances K, Quarnstrom, Clare F, Mickelson, Clayton K, Wijeyesinghe, Sathi, Soerens, Andrew G, Becker, Samuel, Thiede, Joshua M, Weyu, Eyob, O'Flanagan, Stephen D, Walter, Jennifer A, Vu, Michelle N, Menachery, Vineet D, Bold, Tyler D, Vezys, Vaiva, Jenkins, Marc K, Langlois, Ryan A, Masopust, David

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing Abs target the receptor binding domain of…”
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Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses by Stolley, J Michael, Scott, Milcah C, O'Flanagan, Stephen D, Künzli, Marco, Matson, Courtney A, Weyu, Eyob, Langlois, Ryan A, Vezys, Vaiva, Masopust, David

“…Humans experience frequent respiratory infections. Immunology and vaccinology studies in mice are typically performed in naive specific pathogen-free animals…”
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Investigation of an association between onset of narcolepsy and vaccination with pandemic influenza vaccine, Ireland April 2009-December 2010 by O'Flanagan, D, Barret, A S, Foley, M, Cotter, S, Bonner, C, Crowe, C, Lynch, B, Sweeney, B, Johnson, H, McCoy, B, Purcell, E

“…In 2011, the Irish Medicines Board received reports of onset of narcolepsy following vaccination against influenza A(H1N1)pdm09 with Pandemrix. A national…”
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Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses by Joag, Vineet, Wijeyesinghe, Sathi, Stolley, J Michael, Quarnstrom, Clare F, Dileepan, Thamotharampillai, Soerens, Andrew G, Sangala, Jules A, O'Flanagan, Stephen D, Gavil, Noah V, Hong, Sung-Wook, Bhela, Siddheshvar, Gangadhara, Sailaja, Weyu, Eyob, Matchett, William E, Thiede, Joshua, Krishna, Venkatramana, Cheeran, Maxim C-J, Bold, Tyler D, Amara, Rama, Southern, Peter, Hart, Geoffrey T, Schifanella, Luca, Vezys, Vaiva, Jenkins, Marc K, Langlois, Ryan A, Masopust, David

“…The magnitude of SARS-CoV-2-specific T cell responses correlates inversely with human disease severity, suggesting T cell involvement in primary control…”
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Increased incidence of invasive group A streptococcal disease in Ireland, 2012 to 2013 by Meehan, M, Murchan, S, Bergin, S, O'Flanagan, D, Cunney, R

“…Invasive group A streptococcal (iGAS) infections have been notifiable in Ireland since 2004. Incidence rates (2004-2011) have ranged from 0.8 to 1.65 per…”
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The epidemiology of invasive pneumococcal disease in older adults in the post-PCV era. Has there been a herd effect? by CORCORAN, M., VICKERS, I., MERECKIENE, J., MURCHAN, S., COTTER, S., FITZGERALD, M., MCELLIGOTT, M., CAFFERKEY, M., O'FLANAGAN, D., CUNNEY, R., HUMPHREYS, H.

“…The 7 and 13-valent pneumococcal conjugate vaccines (PCVs) have reduced the incidence of invasive pneumococcal disease (IPD) in children in many countries. The…”
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Seasonal influenza immunisation in Europe. Overview of recommendations and vaccination coverage for three seasons: pre-pandemic (2008/09), pandemic (2009/10) and post-pandemic (2010/11) by Mereckiene, J, Cotter, S, Nicoll, A, Lopalco, P, Noori, T, Weber, Jt, D'Ancona, F, Levy-Bruhl, D, Dematte, L, Giambi, C, Valentiner-Branth, P, Stankiewicz, I, Appelgren, E, O Flanagan, D

“…Since 2008, annual surveys of influenza vaccination policies, practices and coverage have been undertaken in 29 European Union (EU)/ European Economic Area…”
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The current state of introduction of human papillomavirus vaccination into national immunisation schedules in Europe: first results of the VENICE2 2010 survey by Dorleans, F, Giambi, C, Dematte, L, Cotter, S, Stefanoff, P, Mereckiene, J, O'Flanagan, D, Lopalco, P L, D'Ancona, F, Levy-Bruhl, D

“…The Venice 2 human papillomavirus vaccination survey evaluates the state of introduction of the HPV vaccination into the national immunisation schedules in the…”
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Influenza A(H1N1)pdm09 vaccination policies and coverage in Europe by Mereckiene, J, Cotter, S, Weber, J T, Nicoll, A, D'Ancona, F, Lopalco, P L, Johansen, K, Wasley, A M, Jorgensen, P, Lévy-Bruhl, D, Giambi, C, Stefanoff, P, Dematte, L, O'Flanagan, D

“…In August 2010 the Vaccine European New Integrated Collaboration Effort (VENICE) project conducted a survey to collect information on influenza A(H1N1)pdm09…”
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Tuberculosis contact investigations associated with air travel in Ireland, September 2011 to November 2014 by Flanagan, Paula, O'Donnell, Joan, Mereckiene, Jolita, O'Flanagan, Darina

“…The risk of communicable disease transmission during air travel is of public health concern and has received much attention over the years. We retrospectively…”
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Differences in national influenza vaccination policies across the European Union, Norway and Iceland 2008-2009 by Mereckiene, J, Cotter, S, D'Ancona, F, Giambi, C, Nicoll, A, Levy-Bruhl, D, Lopalco, P L, Weber, J T, Johansen, K, Dematte, L, Salmaso, S, Stefanoff, P, Greco, D, Dorleans, F, Polkowska, A, O'Flanagan, D

“…In 2009 the second cross-sectional web-based survey was undertaken by the Vaccine European New Integrated Collaboration Effort (VENICE) project across 27…”
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The current state of introduction of HPV vaccination into national immunisation schedules in Europe: Results of the VENICE 2008 survey by Lévy-Bruhl, D, Bousquet, V, King, L.A, O’Flanagan, D, Bacci, S, Lopalco, P.L, Salmaso, S

“…Abstract Three surveys have been undertaken in European Union (EU) member states since January 2007, within the European Commission funded Vaccine European New…”
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Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells by Künzli, Marco, O'Flanagan, Stephen D, LaRue, Madeleine, Talukder, Poulami, Dileepan, Thamotharampillai, Stolley, J Michael, Soerens, Andrew G, Quarnstrom, Clare F, Wijeyesinghe, Sathi, Ye, Yanqi, McPartlan, Justine S, Mitchell, Jason S, Mandl, Christian W, Vile, Richard, Jenkins, Marc K, Ahmed, Rafi, Vezys, Vaiva, Chahal, Jasdave S, Masopust, David

“…Respiratory tract resident memory T cells (T ), typically generated by local vaccination or infection, can accelerate control of pulmonary infections that…”
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National seasonal influenza vaccination survey in Europe, 2008 by Mereckiene, J, Cotter, S, Nicoll, A, Levy-Bruhl, D, Ferro, A, Tridente, G, Zanoni, G, Berra, P, Salmaso, S, O'Flanagan, D, O Flanagan, D

“…A cross-sectional survey was undertaken with the European Union (EU) Member States and Norway and Iceland to describe seasonal influenza immunisation in the…”
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Chronic antigen in solid tumors drives a distinct program of T cell residence by Gavil, Noah V, Scott, Milcah C, Weyu, Eyob, Smith, Olivia C, O'Flanagan, Stephen D, Wijeyesinghe, Sathi, Lotfi-Emran, Sahar, Shiao, Stephen L, Vezys, Vaiva, Masopust, David

“…Analyses of healthy tissue reveal signatures that identify resident memory CD8 T cells (T ), which survey tissues without recirculating. The density of T…”
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A prolonged outbreak of invasive meningococcal disease in an extended Irish Traveller family across three Health Service Executive (HSE) areas in Ireland, 2010 to 2013 by O'Connor, L, Ward, M, Bennett, D, Mulhall, R, O'Lorcain, P, Cunney, R, McDermott, R, Neville, E, Heslin, J, FitzGerald, R, Meyler, K, Conlon, M, Clarke, A, Corcoran, B, Fitzpatrick, G, O'Connor, B, Flanagan, P, O'Flanagan, D, Cotter, S

“…Between March 2010 and November 2013 eight laboratory-confirmed cases of serogroup B, invasive meningococcal disease (IMD) were identified in an extended Irish…”
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CD8 + T cell self-tolerance permits responsiveness but limits tissue damage by Truckenbrod, Emily N, Burrack, Kristina S, Knutson, Todd P, Borges da Silva, Henrique, Block, Katharine E, O'Flanagan, Stephen D, Stagliano, Katie R, Hurwitz, Arthur A, Fulton, Ross B, Renkema, Kristin R, Jameson, Stephen C

“…Self-specific CD8 T cells can escape clonal deletion, but the properties and capabilities of such cells in a physiological setting are unclear. We…”
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Invasive Group A streptococcal disease in Ireland, 2004 to 2010 by Martin, J, Murchan, S, O'Flanagan, D, Fitzpatrick, F

“…Invasive group A streptococcal infections (iGAS) are a major clinical and public health challenge. iGAS is a notifiable disease in Ireland since 2004. The aim…”
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Leptospirosis in Ireland: annual incidence and exposures associated with infection by GARVEY, P., CONNELL, J., O'FLANAGAN, D., McKEOWN, P.

“…Human leptospirosis is found throughout the world, albeit with a higher incidence in tropical regions. In temperate regions it is associated with certain…”
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