Search Results - "O’Duill, Miriam"

A Guide to Directing Group Removal: 8‐Aminoquinoline by Fitzgerald, Liam S., O'Duill, Miriam L.

“…The use of directing groups allows high levels of selectivity to be achieved in transition metal‐catalyzed transformations. Efficient removal of these…”
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Tridentate Directing Groups Stabilize 6‑Membered Palladacycles in Catalytic Alkene Hydrofunctionalization by O’Duill, Miriam L, Matsuura, Rei, Wang, Yanyan, Turnbull, Joshua L, Gurak, John A, Gao, De-Wei, Lu, Gang, Liu, Peng, Engle, Keary M

“…Removable tridentate directing groups inspired by pincer ligands have been designed to stabilize otherwise kinetically and thermodynamically disfavored…”
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2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy by Das, Suman, McIvor, Charlotte, Greener, Andrew, Suwita, Charlotte, Argent, Stephen P., O'Duill, Miriam L.

“…The 2,2‐difluoroethyl group is an important lipophilic hydrogen bond donor in medicinal chemistry, but its incorporation into small molecules is often…”
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Catalytic Hydrotrifluoromethylation of Unactivated Alkenes by Mizuta, Satoshi, Verhoog, Stefan, Engle, Keary M, Khotavivattana, Tanatorn, O’Duill, Miriam, Wheelhouse, Katherine, Rassias, Gerasimos, Médebielle, Maurice, Gouverneur, Véronique

“…A visible-light-mediated hydrotrifluoromethylation of unactivated alkenes that uses the Umemoto reagent as the CF3 source and MeOH as the reductant is…”
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Programmable Deuteration of Indoles via Reverse Deuterium Exchange by Fitzgerald, Liam S., McNulty, Rachael L., Greener, Andrew, O’Duill, Miriam L.

“…Methods for selective deuterium incorporation into drug-like molecules have become extremely valuable due to the commercial, mechanistic, and biological…”
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Frontispiece: A Guide to Directing Group Removal: 8‐Aminoquinoline by Fitzgerald, Liam S., O'Duill, Miriam L.

“…8‐Aminoquinoline is one of the most powerful and versatile directing groups in transition metal‐catalyzed methodologies and while its installation and use are…”
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Cross-Coupling of [2-Aryl-1,1,2,2-tetrafluoroethyl](trimethyl)silanes with Aryl Halides by O’Duill, Miriam, Dubost, Emmanuelle, Pfeifer, Lukas, Gouverneur, Véronique

“…The synthesis of arylCF2CF2SiMe3 and their reactivity in cross-coupling reactions with aryl iodides and aryl bromides to afford a range of…”
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2,2‐Difluoroethylation of Heteroatom Nucleophiles via a Hypervalent Iodine Strategy by Das, Suman, McIvor, Charlotte, Greener, Andrew, Suwita, Charlotte, Argent, Stephen P., O'Duill, Miriam L.

“…The 2,2‐difluoroethyl group is an important lipophilic hydrogen bond donor in medicinal chemistry, but its incorporation into small molecules is often…”
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Recruitment and Immobilization of a Fluorinated Biomarker Across an Interfacial Phospholipid Film using a Fluorocarbon Gas by Yang, Guang, O'Duill, Miriam, Gouverneur, Véronique, Krafft, Marie Pierre

“…Perfluorohexane gas when introduced in the air atmosphere above a film of phospholipid self‐supported on an aqueous solution of C2F5‐labeled compounds causes…”
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Copper-Catalyzed Chan–Lam Cyclopropylation of Phenols and Azaheterocycles by Derosa, Joseph, O’Duill, Miriam L, Holcomb, Matthew, Boulous, Mark N, Patman, Ryan L, Wang, Fen, Tran-Dubé, Michelle, McAlpine, Indrawan, Engle, Keary M

“…Small molecules containing cyclopropane–heteroatom linkages are commonly needed in medicinal chemistry campaigns yet are problematic to prepare using existing…”
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Palladium(II)-Catalyzed Directed anti-Hydrochlorination of Unactivated Alkynes with HCl by Derosa, Joseph, Cantu, Annabelle L, Boulous, Mark N, O’Duill, Miriam L, Turnbull, Joshua L, Liu, Zhen, De La Torre, Daizy M, Engle, Keary M

“…A regio­selective anti-hydrochlorination of unactivated alkynes is reported. The reaction utilizes in situ generated HCl as the source of both the Cl– and H+…”
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Catalytic Decarboxylative Fluorination for the Synthesis of Tri- and Difluoromethyl Arenes by Mizuta, Satoshi, Stenhagen, Ida S. R, O’Duill, Miriam, Wolstenhulme, Jamie, Kirjavainen, Anna K, Forsback, Sarita J, Tredwell, Matthew, Sandford, Graham, Moore, Peter R, Huiban, Mickael, Luthra, Sajinder K, Passchier, Jan, Solin, Olof, Gouverneur, Véronique

“…Treatment of readily available α,α-difluoro- and α-fluoroarylacetic acids with Selectfluor under Ag(I) catalysis led to decarboxylative fluorination. This…”
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Structure and thermal stability of phosphorus-iodonium ylids by Greener, Andrew, Argent, Stephen P, Clarke, Coby J, O’Duill, Miriam L

“…Hypervalent iodine(III) reagents have become indispensable tools in organic synthesis, but gaps remain in the functionalities they can transfer. In this study,…”
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Trifluoromethylation of Allylsilanes under Photoredox Catalysis by Mizuta, Satoshi, Engle, Keary M, Verhoog, Stefan, Galicia-López, Oscar, O’Duill, Miriam, Médebielle, Maurice, Wheelhouse, Katherine, Rassias, Gerasimos, Thompson, Amber L, Gouverneur, Véronique

“…A new catalytic method to access allylic secondary CF3 products is described. These reactions use the visible light excited Ru(bpy)3Cl2·6H2O catalyst and the…”
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Recruitment and Immobilization of a Fluorinated Biomarker Across an Interfacial Phospholipid Film using a Fluorocarbon Gas by Yang, Guang, O'Duill, Miriam, Gouverneur, Véronique, Krafft, Marie Pierre

“…Perfluorohexane gas when introduced in the air atmosphere above a film of phospholipid self‐supported on an aqueous solution of C2F5‐labeled compounds causes…”
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Catalytic hydrotrifluoromethylation of unactivited alkenes by Mizuta, Satoshi, Verhoog, Stefan, Engle, Keary M., Khotavivattana, Tanatorn, O’duill, Miriam, Wheelhouse, Katherine, Rassias, Gerasimos, Médebielle, Maurice, Gouverneur, Véronique

“…A visible-light-mediated hydrotrifluoromethylation of unactivated alkenes that uses the Umemoto reagent as the CF3 source and MeOH as the reductant is…”
Get full text