Search Results - "O’Dair, Mark"

Discrete LAT condensates encode antigen information from single pMHC:TCR binding events by McAffee, Darren B., O’Dair, Mark K., Lin, Jenny J., Low-Nam, Shalini T., Wilhelm, Kiera B., Kim, Sungi, Morita, Shumpei, Groves, Jay T.

“…LAT assembly into a two-dimensional protein condensate is a prominent feature of antigen discrimination by T cells. Here, we use single-molecule imaging…”
Get full text

Height, but not binding epitope, affects the potency of synthetic TCR agonists by Wilhelm, Kiera B., Morita, Shumpei, McAffee, Darren B., Kim, Sungi, O’Dair, Mark K., Groves, Jay T.

“…Under physiological conditions, peptide-major histocompatibility complex (pMHC) molecules can trigger T cell receptors (TCRs) as monovalent ligands that are…”
Get full text

Height, but not binding epitope, affects the potency of synthetic TCR agonists by Wilhelm, Kiera B., Morita, Shumpei, McAffee, Darren B., Kim, Sungi, O’Dair, Mark K., Groves, Jay T.

Get full text

Effect of Buffer Conditions and Organic Cosolvents on the Rate of Strain-Promoted Azide–Alkyne Cycloaddition by Davis, Derek L., Price, Erin K., Aderibigbe, Sabrina O., Larkin, Maureen X.-H., Barlow, Emmett D., Chen, Renjie, Ford, Lincoln C., Gray, Zackery T., Gren, Stephen H., Jin, Yuwei, Keddington, Keith S., Kent, Alexandra D., Kim, Dasom, Lewis, Ashley, Marrouche, Rami S., O’Dair, Mark K., Powell, Daniel R., Scadden, Mick’l H. C., Session, Curtis B., Tao, Jifei, Trieu, Janelle, Whiteford, Kristen N., Yuan, Zheng, Yun, Goyeun, Zhu, Judy, Heemstra, Jennifer M.

“…We investigate the effect of buffer identity, ionic strength, pH, and organic cosolvents on the rate of strain-promoted azide–alkyne cycloaddition with the…”
Get full text

Synthesis of Highly Functionalized Tri- and Tetrasubstituted Alkenes via Pd-Catalyzed 1,2-Hydrovinylation of Terminal 1,3-Dienes by Saini, Vaneet, O’Dair, Mark, Sigman, Matthew S

“…An efficient method for the construction of Csp2–Csp3 bond in a regio- and stereoselective fashion involving 1,3-terminal dienes, enol triflates/nonaflates,…”
Get full text

Differential Analysis of T-Cell Activation by a Library of Membrane-Tethered, Monovalent, Fab’-Based Synthetic T-Cell Receptor Agonists by Wilhelm, Kiera B., Morita, Shumpei, McAffee, Darren, O'Dair, Mark K., Kim, Sungi, Groves, Jay T.

Get full text

Timing to Membrane-Associated Protein Condensation Controls Antigen Discrimination in T Cells by O'Dair, Mark K., McAffee, Darren, Wilhelm, Kiera B., Groves, Jay T.

Get full text

Timing and Nucleation of Membrane Protein Condensation by Single Peptide-MHC: T Cell Receptor Complex Control Antigen Discrimination by O'Dair, Mark K

“…An adaptive immune response begins with a T cell accurately identifying a pathogen-derived peptide loaded into MHC protein on the surface of an antigen…”
Get full text

Molecular Mechanisms for the Stochastic Condensation of LAT Assemblies in T Cells by ODair, Mark K., McAffee, Darren B., Groves, Jay T.

Get full text