Search Results - "O’Connor, Sheila J M"

Monoclonal B-Cell Lymphocytosis and Chronic Lymphocytic Leukemia by Rawstron, Andy C, Bennett, Fiona L, O'Connor, Sheila J.M, Kwok, Marwan, Fenton, James A.L, Plummer, Marieth, de Tute, Ruth, Owen, Roger G, Richards, Stephen J, Jack, Andrew S, Hillmen, Peter

“…Small numbers of monoclonal B cells with the phenotype of chronic lymphocytic leukemia (CLL) were detected by means of high-sensitivity flow cytometry in about…”
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Minimal residual disease is an independent predictor for 10-year survival in CLL by Kwok, Marwan, Rawstron, Andy C., Varghese, Abraham, Evans, Paul A.S., O'Connor, Sheila J.M., Doughty, Chi, Newton, Darren J., Moreton, Paul, Hillmen, Peter

“…Minimal residual disease (MRD) negativity, defined as <1 chronic lymphocytic leukemia (CLL) cell detectable per 10 000 leukocytes, has been shown to…”
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IgM myeloma: a rare entity characterized by a CD20−CD56−CD117− immunophenotype and the t(11;14) by Feyler, Sylvia, O’Connor, Sheila J. M., Rawstron, Andy C., Subash, Chezhian, Ross, Fiona M., Pratt, Guy, Drayson, Mark T., Ashcroft, John, Cook, Gordon, Owen, Roger G.

“…Summary IgM myeloma is a very rare and poorly defined entity. In a detailed assessment of 10 cases, it was demonstrated that 70% had an aberrant phenotype…”
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Extramedullary plasmacytoma are characterized by a ‘myeloma‐like’ immunophenotype and genotype and occult bone marrow involvement by Boll, Maayke, Parkins, Elizabeth, O’Connor, Sheila J. M., Rawstron, Andy C., Owen, Roger G.

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Translocation t(14;16) in IgM multiple myeloma by Owen, Roger G., O’Connor, Sheila J. M., Bond, Lee R, de Tute, Ruth M, Rawstron, Andy C.

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IgD multiple myeloma: biology, diagnosis, and treatment by Egan, Philip A., O'Connor, Sheila J. M., Deighan, W. Ian, McConville, Conal E., Elder, Patrick T., (Curly) Morris, T. C. M., Alexander, H. Denis

“…IgD multiple myeloma is uncommon. Patients generally present at a younger age and have shorter progression free and overall survivals (OSs). Its rarity has…”
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Rearrangement of the BCL6 locus at 3q27 is an independent poor prognostic factor in nodal diffuse large B‐cell lymphoma by Barrans, Sharon L., O'Connor, Sheila J. M., Evans, Paul A. S., Davies, Faith E., Owen, Roger G., Haynes, Andrew P., Morgan, Gareth J., Jack, Andrew S.

“…Diffuse large B‐cell lymphomas (DLBCL) are a heterogeneous group of tumours, varying in clinical features, immunophenotype and cytogenetics. The aim of this…”
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Monoclonal B lymphocytes with the characteristics of “indolent” chronic lymphocytic leukemia are present in 3.5% of adults with normal blood counts by Rawstron, Andy C., Green, Michael J., Kuzmicki, Anita, Kennedy, Ben, Fenton, James A.L., Evans, Paul A.S., O'Connor, Sheila J.M., Richards, Stephen J., Morgan, Gareth J., Jack, Andrew S., Hillmen, Peter

“…Molecular and cellular markers associated with malignant disease are frequently identified in healthy individuals. The relationship between these markers and…”
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The t(14;18) Is Associated with Germinal Center-derived Diffuse Large B-Cell Lymphoma and Is a Strong Predictor of Outcome by BARRANS, Sharon L, EVANS, Paul A. S, O'CONNOR, Sheila J. M, KENDALL, S. Jane, OWEN, Roger G, HAYNES, Andrew P, MORGAN, Gareth J, JACK, Andrew S

“…The t(14;18) is present in a significant proportion of diffuse large B-cell lymphomas (DLBCLs), however, the prognostic effect of the translocation and the…”
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Multiple myeloma with central nervous system relapse by Egan, Philip A, Elder, Patrick T, Deighan, W Ian, O'Connor, Sheila J M, Alexander, H Denis

“…Central nervous system involvement in multiple myeloma is a rare complication but carries a very poor prognosis. We provide a review of current literature,…”
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Defining IgM multiple myeloma by Owen, Roger G, Feyler, Sylvia, O'Connor, Sheila JM, Bond, Lee R, de Tute, Ruth M, Rawstron, Andy C

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Practical Application of Fluorescent In Situ Hybridization Techniques in Clinical Diagnostic Laboratories by O'Connor, Sheila J M, Turner, Kathryn R, Barrans, Sharon L

“…Fluorescent in situ hybridization (FISH) techniques can be used to identify a range of chromosome abnormalities that are clinically significant in many…”
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Detection of BCL2 Gene Rearrangements in the Reed-Sternberg Cells of Composite Lymphomas or Newly Diagnosed Hodgkin Lymphoma in Patients with a Previous Diagnosis of Follicular Lymphoma by O’Connor, Sheila J M, Turner, Kathryn, Burton, Catherine H, Jack, Andrew

“…Introduction: Composite lymphomas involving Hodgkin lymphoma (HL) and non-Hodgkin lymphomas (CLL, DLBCL, FL, MZL, MCL, T-NHL) are relatively rare but are…”
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Indolent mantle-cell lymphoma: immunoglobulin variable region heavy chain sequence analysis reveals evidence of disease 10 years prior to symptomatic clinical presentation by Rule, Simon A J, Poplar, Sarah, Evans, Paul A S, O'Connor, Sheila J M, Owen, Roger G

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Extramedullary plasmacytoma with a t(11;14)(q13;q32) and aggressive clinical course by Parkins, Elizabeth, Boll, Maayke, O'Connor, Sheila J. M., Rawstron, Andy C., Owen, Roger G.

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Development of EBV-associated diffuse large B-cell lymphoma in Waldenström macroglobulinemia and mantle cell lymphoma by Varghese, Abraham M., Sayala, Hazem, Evans, Paul A. S., O'Connor, Sheila J. M., Patmore, Russell, Hillmen, Peter, Owen, Roger G.

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Cyclooxygenase‐2 (COX‐2) in multiple myeloma: prognostic factor or therapeutic target? by Owen, Roger G., Fan, Im, O'Connor, Sheila J. M., Rollett, Rebecca A., Anthony Child, J., Davies, Faith E., Rawstron, Andy C.

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The t(9;14)(p13;q32) is a recurrent but rare abnormality in splenic marginal zone lymphoma by Kelly, Richard J., O'Connor, Sheila J. M., Barrans, Sharon L., Johnson, Roderick J., Owen, Roger G.

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Intravascular large B-cell lymphoma associated with a near-tetraploid karyotype, rearrangement of BCL6, and a t(11;14)(q13;q32) by Rashid, Rumana, Johnson, Roderick J., Morris, Stephen, Dickinson, Helen, Czyz, Jarek, O'Connor, Sheila J.M., Owen, Roger G.

“…Chromosome analysis of a patient with intravascular large B-cell lymphoma (IVL) revealed a complex, near-tetraploid karyotype with 83 chromosomes…”
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Waldenström macroglobulinemia: Development of diagnostic criteria and identification of prognostic factors by OWEN, Roger G, BARRANS, Sharon L, RICHARDS, Stephen J, O'CONNOR, Sheila J. M, CHILD, J. Anthony, PARAPIA, Liakat A, MORGAN, Gareth J, JACK, Andrew S

“…To establish whether a combination of morphologic and immunophenotypic criteria could be developed to more precisely define Waldenström macroglobulinemia (WM)…”
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