Search Results - "O’Connor, Rodney P."

Electroporation Microchip With Integrated Conducting Polymer Electrode Array for Highly Sensitive Impedance Measurement by Dijk, Gerwin, Poulkouras, Romanos, O'Connor, Rodney P.

“…Objective: Monitoring of impedance changes during electroporation-based treatments can be used to study the biological response and provide feedback regarding…”
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Exposure to GSM RF fields does not affect calcium homeostasis in human endothelial cells, rat pheocromocytoma cells or rat hippocampal neurons by O'Connor, Rodney P, Madison, Steve D, Leveque, Philippe, Roderick, H Llewelyn, Bootman, Martin D

“…In the course of modern daily life, individuals are exposed to numerous sources of electromagnetic radiation that are not present in the natural environment…”
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In vivo multiphoton nanosurgery on cortical neurons by Sacconi, Leonardo, O'Connor, Rodney P, Jasaitis, Audrius, Masi, Alessio, Buffelli, Mario, Pavone, Francesco S

“…Two-photon microscopy has been used to perform high spatial resolution imaging of spine plasticity in the intact neocortex of living mice. Multiphoton…”
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Influence of PEDOT:PSS Coating Thickness on the Performance of Stimulation Electrodes by Dijk, Gerwin, Ruigrok, Hermanus J., O'Connor, Rodney P.

“…Poly(3,4‐ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:PSS) is a conducting polymer commonly used to coat the electrodes of biomedical…”
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Genetically engineered HEK cells as a valuable tool for studying electroporation in excitable cells by Batista Napotnik, Tina, Kos, Bor, Jarm, Tomaž, Miklavčič, Damijan, O’Connor, Rodney P., Rems, Lea

“…Electric pulses used in electroporation-based treatments have been shown to affect the excitability of muscle and neuronal cells. However, understanding the…”
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PEDOT:PSS coated electrodes reduce intracellular oxidation and cell damage with pulsed electric field application by Poulkouras, Romanos, Dijk, Gerwin, Lefevre, Marie, Bača, Martin, Moreau, David, O'Connor, Rodney P.

“…•Pulsed electric field-induced mitochondrial superoxide rise is investigated.•Mitochondrial superoxide generation is dependent on electrode…”
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PEDOT:PSS‐Coated Stimulation Electrodes Attenuate Irreversible Electrochemical Events and Reduce Cell Electropermeabilization by Dijk, Gerwin, Ruigrok, Hermanus J., O'Connor, Rodney P.

“…Electroporation or electropermeabilization occurs when cells are exposed to sufficiently high‐pulsed electric fields. This phenomenon is now an important…”
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Nanosecond pulsed electric fields depolarize transmembrane potential via voltage-gated K+, Ca2+ and TRPM8 channels in U87 glioblastoma cells by Burke, Ryan C., Bardet, Sylvia M., Carr, Lynn, Romanenko, Sergii, Arnaud-Cormos, Delia, Leveque, Philippe, O'Connor, Rodney P.

“…Nanosecond pulsed electric fields (nsPEFs) have a variety of applications in the biomedical and biotechnology industries. Cancer treatment has been at the…”
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Ca2+ roles in electroporation-induced changes of cancer cell physiology: From membrane repair to cell death by Navickaitė, Diana, Ruzgys, Paulius, Maciulevičius, Martynas, Dijk, Gerwin, O'Connor, Rodney P., Šatkauskas, Saulius

“…[Display omitted] •Molecular electrotransfer can be controlled by intracellular Ca2+ concentration.•These effects are related with an enhanced membrane repair…”
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Long-term changes in transmembrane voltage after electroporation are governed by the interplay between nonselective leak current and ion channel activation by Blažič, Anja, Guinard, Manon, Leskovar, Tomaž, O’Connor, Rodney P., Rems, Lea

“…•Ion channels play an important role in regulating the long-term changes in TMV.•Experimental results are supported by a theoretical model.•Long-term changes…”
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Calcium-independent disruption of microtubule dynamics by nanosecond pulsed electric fields in U87 human glioblastoma cells by Carr, Lynn, Bardet, Sylvia M., Burke, Ryan C., Arnaud-Cormos, Delia, Leveque, Philippe, O’Connor, Rodney P.

“…High powered, nanosecond duration, pulsed electric fields (nsPEF) cause cell death by a mechanism that is not fully understood and have been proposed as a…”
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Rhodamine B as an optical thermometer in cells focally exposed to infrared laser light or nanosecond pulsed electric fields by Moreau, David, Lefort, Claire, Burke, Ryan, Leveque, Philippe, O'Connor, Rodney P

“…The temperature-dependent fluorescence property of Rhodamine B was used to measure changes in temperature at the cellular level induced by either infrared…”
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Infrared neural stimulation induces intracellular Ca2+ release mediated by phospholipase C by Moreau, David, Lefort, Claire, Pas, Jolien, Bardet, Sylvia M., Leveque, Philippe, O'Connor, Rodney P.

“…The influence of infrared laser pulses on intracellular Ca2+ signaling was investigated in neural cell lines with fluorescent live cell imaging. The probe…”
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Visualisation of an nsPEF induced calcium wave using the genetically encoded calcium indicator GCaMP in U87 human glioblastoma cells by Carr, Lynn, Bardet, Sylvia M., Arnaud-Cormos, Delia, Leveque, Philippe, O'Connor, Rodney P.

“…Cytosolic, synthetic chemical calcium indicators are typically used to visualise the rapid increase in intracellular calcium ion concentration that follows…”
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Multiphoton imaging reveals that nanosecond pulsed electric fields collapse tumor and normal vascular perfusion in human glioblastoma xenografts by Bardet, Sylvia M., Carr, Lynn, Soueid, Malak, Arnaud-Cormos, Delia, Leveque, Philippe, O’Connor, Rodney P.

“…Despite the biomedical advances of the last century, many cancers including glioblastoma are still resistant to existing therapies leaving patients with poor…”
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Multicolor multiphoton microscopy based on a nanosecond supercontinuum laser source by Lefort, Claire, O'Connor, Rodney P., Blanquet, Véronique, Magnol, Laetitia, Kano, Hideaki, Tombelaine, Vincent, Lévêque, Philippe, Couderc, Vincent, Leproux, Philippe

“…Multicolor multiphoton microscopy is experimentally demonstrated for the first time on a spectral bandwidth of excitation of 300 nm (full width half maximum)…”
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A versatile high voltage nano- and sub-nanosecond pulse generator by Kohler, Sophie, Couderc, Vincent, O'Connor, Rodney P., Arnaud-Cormos, Delia, Leveque, Philippe

“…High-voltage (HV) ultrashort pulse technologies have found many applications in areas such as medicine, biology, food processing, environmental science and…”
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Delivery devices for exposure of biological cells to nanosecond pulsed electric fields by Soueid, Malak, Dobbelaar, Martinus C. F., Bentouati, Sabrina, Bardet, Sylvia M., O’Connor, Rodney P., Bessières, Delphine, Paillol, Jean, Leveque, Philippe, Arnaud-Cormos, Delia

“…In this paper, delivery devices for nanosecond pulsed electric field exposure of biological samples in direct contact with electrodes or isolated are presented…”
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Dosimetric Characteristics of an EMF Delivery System Based on a Real-Time Impedance Measurement Device by Garcia-Fernandez, Miguel A., Percherancier, Yann, Lagroye, Isabelle, OConnor, Rodney P., Veyret, Bernard, Arnaud-Cormos, Delia, Leveque, Philippe

“…In this paper, the dosimetric characterization of an EMF exposure setup compatible with real-time impedance measurements of adherent biological cells is…”
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Microchip Laser-Based Optoelectronic System for Kilovolt Picosecond Electromagnetic Pulse Generation by Arnaud-Cormos, Delia, O'Connor, Rodney P., Leveque, Philippe, Couderc, Vincent

“…An optoelectronic electromagnetic generator was developed for the creation and shaping of picosecond pulses. The system integrated a homemade compact…”
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