Search Results - "O’Connor, Neil K"

Biodegradation of pentafluorosulfanyl-substituted aminophenol in Pseudomonas spp by Saccomanno, Marta, Hussain, Sabir, O’Connor, Neil K., Beier, Petr, Somlyay, Mate, Konrat, Robert, Murphy, Cormac D.

“…The pentafluorosulfanyl (SF 5 –) substituent conveys properties that are beneficial to drugs and agrochemicals. As synthetic methodologies improve the number…”
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A convenient chemical-microbial method for developing fluorinated pharmaceuticals by Bright, Tara V, Dalton, Fay, Elder, Victoria L, Murphy, Cormac D, O'Connor, Neil K, Sandford, Graham

“…A significant proportion of pharmaceuticals are fluorinated and selecting the site of fluorine incorporation can be an important beneficial part a drug…”
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Novel fluorinated lipopeptides from Bacillus sp. CS93 via precursor-directed biosynthesis by O’Connor, Neil K, Hudson, Alex S, Cobb, Steven L, O’Neil, Deborah, Robertson, Jennifer, Duncan, Vanessa, Murphy, Cormac D

“…While attempting to improve production of fluoro-iturin A in Bacillus sp. CS93 new mono- and di-fluorinated fengycins were detected in culture supernatants by…”
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Microbial biotransformation of aryl sulfanylpentafluorides by Kavanagh, Emma, Winn, Michael, Gabhann, Cliona Nic, O’Connor, Neil K, Beier, Petr, Murphy, Cormac D

“…We report, for the first time, the biotransformation of potential pollutants bearing the pentafluorosulfanyl (SF₅-) functional group in a fungus and bacteria…”
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Production of the novel lipopeptide antibiotic trifluorosurfactin via precursor-directed biosynthesis by O’Connor, Neil K., Rai, Dilip K., Clark, Benjamin R., Murphy, Cormac D.

“…Almost one quarter of drugs contain fluorine, although incorporating fluorine into complex natural products synthetically is challenging. Precursor-directed…”
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