Search Results - "O’Connor, Margaret H."
-
1
Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens
Published in The Journal of experimental medicine (25-08-2014)“…The bZIP transcription factor Nfil3 (also known as E4BP4) is required for the development of natural killer (NK) cells and type 1 innate lymphoid cells…”
Get full text
Journal Article -
2
Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling
Published in PLoS pathogens (01-07-2021)“…We have recently demonstrated that the function of T follicular helper (Tfh) cells from lymph nodes (LN) of HIV-infected individuals is impaired. We found that…”
Get full text
Journal Article -
3
Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease
Published in Blood (17-08-2017)“…Graft-versus-host disease (GVHD) and posttransplant immunodeficiency are frequently related complications of allogeneic hematopoietic transplantation…”
Get full text
Journal Article -
4
Melanoma lymph node metastases - moving beyond quantity in clinical trial design and contemporary practice
Published in Frontiers in oncology (14-10-2022)“…The presence of lymph node metastases is a well-studied prognostic factor for cutaneous melanoma. Characterization of melanoma lymph node metastases and their…”
Get full text
Journal Article -
5
Dopamine Levels Induced by Substance Abuse Alter Efficacy of Maraviroc and Expression of CCR5 Conformations on Myeloid Cells: Implications for NeuroHIV
Published in Frontiers in immunology (19-05-2021)“…Despite widespread use of antiretroviral therapy (ART), HIV remains a major public health issue. Even with effective ART many infected individuals still suffer…”
Get full text
Journal Article -
6
A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells
Published in Communications biology (12-05-2021)“…Innate Lymphoid Cells (ILCs) are immune cells typically found on mucosal surfaces and in secondary lymphoid organs where they regulate the immune response to…”
Get full text
Journal Article -
7
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
Published in Nature (London) (24-12-2015)“…Innate lymphoid cells increase the growth of mouse intestinal organoids via IL-22 production; recombinant IL-22 promotes growth of both mouse and human…”
Get full text
Journal Article -
8
Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease
Published in Immunity (Cambridge, Mass.) (24-08-2012)“…Little is known about the maintenance of intestinal stem cells (ISCs) and progenitors during immune-mediated tissue damage or about the susceptibility of…”
Get full text
Journal Article -
9
Graft Versus Host Disease Leads to Elimination of Tissue-Resident Innate Lymphoid Cells Following Experimental and Clinical Allogeneic Transplantation
Published in Blood (13-11-2019)“…A potential role for endogenous innate lymphoid cells (ILCs) in prevention of gastrointestinal (GI) GVHD has recently been described in murine and clinical…”
Get full text
Journal Article -
10
Germinal Center T follicular helper
Published in PLoS pathogens (19-07-2021)Get full text
Journal Article -
11
Graft vs. host disease leads to elimination of tissue-resident innate lymphoid cells following experimental and clinical allogeneic transplantation
Published in The Journal of immunology (1950) (01-05-2020)“…Innate lymphoid cells (ILCs) are associated with protective mucosal responses after allogeneic bone marrow transplantation (allo-BMT). However, the specific in…”
Get full text
Journal Article -
12
Graft-Versus-Host Disease Leads to Systemic Elimination of Innate Lymphoid Cells and Abolishes Their Development
Published in Biology of blood and marrow transplantation (01-03-2019)“…Innate lymphoid cells (ILCs) are associated with protective mucosal response after experimental allogeneic BMT. However, the specific in vivo roles of ILCs and…”
Get full text
Journal Article -
13
Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft vs. host disease
Published in Immunity (Cambridge, Mass.) (24-08-2012)“…Little is known about the maintenance of intestinal stem cells (ISCs) and progenitors during immune-mediated tissue damage or about the susceptibility of…”
Get full text
Journal Article