Search Results - "O’Connor, Jason"

Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge by Parrott, Jennifer M, Redus, Laney, O'Connor, Jason C

“…Inflammation increases the risk of developing depression-related symptoms, and tryptophan metabolism is an important mediator of these behavior changes…”
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Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors by Lawson, Marcus A, Parrott, Jennifer M, McCusker, Robert H, Dantzer, Robert, Kelley, Keith W, O'Connor, Jason C

“…Activation of the tryptophan degrading enzyme indoleamine-2,3-dioxygenase 1 (IDO1) is associated with the development of behavioral signs of depression…”
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Brain derived neurotrophic factor deficiency exacerbates inflammation-induced anhedonia in mice by Parrott, Jennifer M., Porter, Grace A., Redus, Laney, O’Connor, Jason C.

“…Brain-derived neurotrophic factor (BDNF) is implicated in the pathology of major depression and influences the inflammatory response. Prolonged immune system…”
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Cognitive dysfunction precedes the onset of motor symptoms in the MitoPark mouse model of Parkinson's disease by Li, Xiuhua, Redus, Laney, Chen, Cang, Martinez, Paul A, Strong, Randy, Li, Senlin, O'Connor, Jason C

“…Parkinson's disease (PD) is a neurodegenerative disorder primarily characterized by progressive loss of dopamine neurons, leading to loss of motor…”
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Randomization to Treadmill Training Improves Physical and Metabolic Health in Association With Declines in Oxidative Stress in Stroke by Serra, Monica C., Hafer-Macko, Charlene E., Robbins, Ronna, O'Connor, Jason C., Ryan, Alice S.

“…To investigate the effect of aerobic exercise vs control (stretching/balance) on inflammatory and oxidative stress biomarkers in stroke survivors and whether…”
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Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide by Corona, Angela W, Huang, Yan, O'Connor, Jason C, Dantzer, Robert, Kelley, Keith W, Popovich, Phillip G, Godbout, Jonathan P

“…Interactions between fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) regulate microglial activation in the CNS. Recent findings indicate that…”
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Reduced demand uncertainty and the sustainability of collusion: How AI could affect competition by O’Connor, Jason, Wilson, Nathan E.

“…•An improved ability to predict demand may affect the nature of competition in oligopoly markets.•Greater transparency may enable coordination when previously…”
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Economics at the FTC: Non-price Merger Effects and Deceptive Automobile Ads by Jones, Matthew, Kobayashi, Bruce, O’Connor, Jason

“…Economists at the Federal Trade Commission analyze a wide range of activities, practices, and policies in support of the agency’s consumer protection and…”
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Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures by Fu, Xin, Zunich, Samantha M, O'Connor, Jason C, Kavelaars, Annemieke, Dantzer, Robert, Kelley, Keith W

“…Transient stimulation of the innate immune system by an intraperitoneal injection of lipopolysaccharide (LPS) activates peripheral and central expression of…”
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Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin by O'Connor, Jason C, André, Caroline, Wang, Yunxia, Lawson, Marcus A, Szegedi, Sandra S, Lestage, Jacques, Castanon, Nathalie, Kelley, Keith W, Dantzer, Robert

“…Although the tryptophan-degrading enzyme, indoleamine 2,3-dioxygenase (IDO), is a pivotal mediator of inflammation-induced depression, its mechanism of…”
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Churn in Supplemental Nutrition Assistance Program: Changes in Medicaid Expenditure and Acute Care Utilization by Xie, Liyang, O’Connor, Jason, Albert, Steven, Gary-Webb, Tiffany, Sharbaugh, Michael, Donohue, Julie M., Ennis, Molly, Hutcheson, Deborah, Cole, Evan S.

“…The Supplemental Nutrition Assistance Program (SNAP) provides financial assistance to low-income individuals and families to help them purchase food. However,…”
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Churn in Supplemental Nutrition Assistance Program by Xie Liyang, O’Connor Jason, Albert, Steven, Gary-Webb, Tiffany, Sharbaugh, Michael, Donohue, Julie M, Ennis, Molly, Hutcheson, Deborah, Cole, Evan S

“…Background:The Supplemental Nutrition Assistance Program (SNAP) provides financial assistance to low-income individuals and families to help them purchase…”
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Snow cover and late fall movement influence wood frog survival during an unusually cold winter by O’Connor, Jason H., Rittenhouse, Tracy A. G.

“…Understanding how organisms will respond to altered winter conditions is hampered by a paucity of information on the winter ecology for many species…”
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Author response to: Modulating kynurenine monooxygenase in microglia: The need for further characterization by Garrison, Allison M., Parrott, Jennifer M., Tunon, Arnulfo, Delgado, Jennifer, Redus, Laney, O’Connor, Jason C.

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Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior by Frenois, François, Moreau, Maïté, O’Connor, Jason, Lawson, Marc, Micon, Charlotte, Lestage, Jacques, Kelley, Keith W, Dantzer, Robert, Castanon, Nathalie

“…Summary Proinflammatory cytokines induce both sickness behavior and depression, but their respective neurobiological correlates are still poorly understood…”
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Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge by Salazar, Alexander, Gonzalez-Rivera, Bryan L., Redus, Laney, Parrott, Jennifer M., O'Connor, Jason C.

“…This article is part of a Special Issue “Neuroendocrine-Immune Axis in Health and Disease.” Upregulation of indoleamine 2,3-dioxygenase (IDO) by…”
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Induction of IDO by Bacille Calmette-Guerin Is Responsible for Development of Murine Depressive-Like Behavior by O'Connor, Jason C, Lawson, Marcus A, Andre, Caroline, Briley, Eileen M, Szegedi, Sandra S, Lestage, Jacques, Castanon, Nathalie, Herkenham, Miles, Dantzer, Robert, Kelley, Keith W

“…Chronic inflammation activates the tryptophan-degrading enzyme IDO, which is well known to impair T cell proliferation. We have previously established that…”
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Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX(3)CR1)-deficient mice by Corona, Angela W, Norden, Diana M, Skendelas, John P, Huang, Yan, O'Connor, Jason C, Lawson, Marcus, Dantzer, Robert, Kelley, Keith W, Godbout, Jonathan P

“…An impaired ability to regulate the activation of microglia by fractalkine (CX3CL1) leads to persistent neuroinflammation and behavioral alterations following…”
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Novel Bluetooth-Enabled Tubeless Insulin Pump: Innovating Pump Therapy for Patients in the Digital Age by Ly, Trang T., Layne, Jennifer E., Huyett, Lauren M., Nazzaro, David, O’Connor, Jason B.

“…The Omnipod DASH™ Insulin Management System (Insulet Corp, Billerica, MA) is a discreet, tubeless, wearable insulin pump that holds up to 200 units of U-100…”
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Increased white blood cell in young adults with family histories of alcohol and other substance use disorders by Mithaiwala, Mustafa N., Phillips, Nikki S., Nguyen, Dylan H., Beehler, Melanie S., Ballard, Harrison S., Vincent, Andrea S., Lovallo, William R., Kochunov, Peter, Hong, L. Elliot, O'Connor, Jason C., Cole, Steve, Acheson, Ashley

“…Individuals with a family history of alcohol or other substance use disorders (FH+) are at increased risk for developing alcohol and other substance use…”
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