Search Results - "O’Connor, George T"

Six-Year Follow-up of a Trial of Antenatal Vitamin D for Asthma Reduction by Litonjua, Augusto A, Carey, Vincent J, Laranjo, Nancy, Stubbs, Benjamin J, Mirzakhani, Hooman, O’Connor, George T, Sandel, Megan, Beigelman, Avraham, Bacharier, Leonard B, Zeiger, Robert S, Schatz, Michael, Hollis, Bruce W, Weiss, Scott T

“…In a previously published controlled trial, maternal administration of vitamin D during pregnancy was found to protect against wheeze in the offspring at the…”
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Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2 by Jackson, Daniel J., Busse, William W., Bacharier, Leonard B., Kattan, Meyer, O’Connor, George T., Wood, Robert A., Visness, Cynthia M., Durham, Stephen R., Larson, David, Esnault, Stephane, Ober, Carole, Gergen, Peter J., Becker, Patrice, Togias, Alkis, Gern, James E., Altman, Mathew C.

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Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults by Wan, Emily S, Balte, Pallavi, Schwartz, Joseph E, Bhatt, Surya P, Cassano, Patricia A, Couper, David, Daviglus, Martha L, Dransfield, Mark T, Gharib, Sina A, Jacobs, David R, Kalhan, Ravi, London, Stephanie J, Navas-Acien, Ana, O’Connor, George T, Sanders, Jason L, Smith, Benjamin M, White, Wendy, Yende, Sachin, Oelsner, Elizabeth C

“…IMPORTANCE: Chronic lung diseases are a leading cause of morbidity and mortality. Unlike chronic obstructive pulmonary disease, clinical outcomes associated…”
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Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality by Bhatt, Surya P, Balte, Pallavi P, Schwartz, Joseph E, Cassano, Patricia A, Couper, David, Jacobs, David R, Kalhan, Ravi, O’Connor, George T, Yende, Sachin, Sanders, Jason L, Umans, Jason G, Dransfield, Mark T, Chaves, Paulo H, White, Wendy B, Oelsner, Elizabeth C

“…IMPORTANCE: According to numerous current guidelines, the diagnosis of chronic obstructive pulmonary disease (COPD) requires a ratio of the forced expiratory…”
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Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years: The VDAART Randomized Clinical Trial by Litonjua, Augusto A, Carey, Vincent J, Laranjo, Nancy, Harshfield, Benjamin J, McElrath, Thomas F, O’Connor, George T, Sandel, Megan, Iverson, Ronald E, Lee-Paritz, Aviva, Strunk, Robert C, Bacharier, Leonard B, Macones, George A, Zeiger, Robert S, Schatz, Michael, Hollis, Bruce W, Hornsby, Eve, Hawrylowicz, Catherine, Wu, Ann Chen, Weiss, Scott T

“…IMPORTANCE: Asthma and wheezing begin early in life, and prenatal vitamin D deficiency has been variably associated with these disorders in offspring…”
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Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study by Araki, Tetsuro, Putman, Rachel K, Hatabu, Hiroto, Gao, Wei, Dupuis, Josée, Latourelle, Jeanne C, Nishino, Mizuki, Zazueta, Oscar E, Kurugol, Sila, Ross, James C, San José Estépar, Raúl, Schwartz, David A, Rosas, Ivan O, Washko, George R, O'Connor, George T, Hunninghake, Gary M

“…The relationship between the development and/or progression of interstitial lung abnormalities (ILA) and clinical outcomes has not been previously…”
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Long-term exposure to traffic emissions and fine particulate matter and lung function decline in the Framingham heart study by Rice, Mary B, Ljungman, Petter L, Wilker, Elissa H, Dorans, Kirsten S, Gold, Diane R, Schwartz, Joel, Koutrakis, Petros, Washko, George R, O'Connor, George T, Mittleman, Murray A

“…Few studies have examined associations between long-term exposure to fine particulate matter (PM2.5) and lung function decline in adults. To determine if…”
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Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children by Altman, Matthew C., Gill, Michelle A., Whalen, Elizabeth, Babineau, Denise C., Shao, Baomei, Liu, Andrew H., Jepson, Brett, Gruchalla, Rebecca S., O’Connor, George T., Pongracic, Jacqueline A., Kercsmar, Carolyn M., Khurana Hershey, Gurjit K., Zoratti, Edward M., Johnson, Christine C., Teach, Stephen J., Kattan, Meyer, Bacharier, Leonard B., Beigelman, Avraham, Sigelman, Steve M., Presnell, Scott, Gern, James E., Gergen, Peter J., Wheatley, Lisa M., Togias, Alkis, Busse, William W., Jackson, Daniel J.

“…Respiratory infections are common precursors to asthma exacerbations in children, but molecular immune responses that determine whether and how an infection…”
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Association of clonal hematopoiesis with chronic obstructive pulmonary disease by Miller, Peter G., Qiao, Dandi, Rojas-Quintero, Joselyn, Honigberg, Michael C., Sperling, Adam S., Gibson, Christopher J., Bick, Alexander G., Niroula, Abhishek, McConkey, Marie E., Sandoval, Brittany, Miller, Brian C., Shi, Weiwei, Viswanathan, Kaushik, Leventhal, Matthew, Werner, Lillian, Moll, Matthew, Cade, Brian E., Barr, R. Graham, Correa, Adolfo, Cupples, L. Adrienne, Gharib, Sina A., Jain, Deepti, Gogarten, Stephanie M., Lange, Leslie A., London, Stephanie J., Manichaikul, Ani, O'Connor, George T., Oelsner, Elizabeth C., Redline, Susan, Rich, Stephen S., Rotter, Jerome I., Ramachandran, Vasan, Yu, Bing, Sholl, Lynette, Neuberg, Donna, Jaiswal, Siddhartha, Levy, Bruce D., Owen, Caroline A., Natarajan, Pradeep, Silverman, Edwin K., van Galen, Peter, Tesfaigzi, Yohannes, Cho, Michael H., Ebert, Benjamin L.

“…Chronic obstructive pulmonary disease (COPD) is associated with age and smoking, but other determinants of the disease are incompletely understood. Clonal…”
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Serum α1-Antitrypsin Concentration in the Diagnosis of α1-Antitrypsin Deficiency by Hurley, Killian, O’Connor, George T

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Sleep-disordered breathing and mortality: a prospective cohort study by Punjabi, Naresh M, Caffo, Brian S, Goodwin, James L, Gottlieb, Daniel J, Newman, Anne B, O'Connor, George T, Rapoport, David M, Redline, Susan, Resnick, Helaine E, Robbins, John A, Shahar, Eyal, Unruh, Mark L, Samet, Jonathan M

“…Sleep-disordered breathing is a common condition associated with adverse health outcomes including hypertension and cardiovascular disease. The overall…”
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Association Between Interstitial Lung Abnormalities and All-Cause Mortality by Putman, Rachel K, Hatabu, Hiroto, Araki, Tetsuro, Gudmundsson, Gunnar, Gao, Wei, Nishino, Mizuki, Okajima, Yuka, Dupuis, Josée, Latourelle, Jeanne C, Cho, Michael H, El-Chemaly, Souheil, Coxson, Harvey O, Celli, Bartolome R, Fernandez, Isis E, Zazueta, Oscar E, Ross, James C, Harmouche, Rola, Estépar, Raúl San José, Diaz, Alejandro A, Sigurdsson, Sigurdur, Gudmundsson, Elías F, Eiríksdottír, Gudny, Aspelund, Thor, Budoff, Matthew J, Kinney, Gregory L, Hokanson, John E, Williams, Michelle C, Murchison, John T, MacNee, William, Hoffmann, Udo, O’Donnell, Christopher J, Launer, Lenore J, Harrris, Tamara B, Gudnason, Vilmundur, Silverman, Edwin K, O’Connor, George T, Washko, George R, Rosas, Ivan O, Hunninghake, Gary M

“…IMPORTANCE: Interstitial lung abnormalities have been associated with lower 6-minute walk distance, diffusion capacity for carbon monoxide, and total lung…”
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MUC5B Promoter Polymorphism and Interstitial Lung Abnormalities by Hunninghake, Gary M, Hatabu, Hiroto, Okajima, Yuka, Gao, Wei, Dupuis, Josée, Latourelle, Jeanne C, Nishino, Mizuki, Araki, Tetsuro, Zazueta, Oscar E, Kurugol, Sila, Ross, James C, San José Estépar, Raúl, Murphy, Elissa, Steele, Mark P, Loyd, James E, Schwarz, Marvin I, Fingerlin, Tasha E, Rosas, Ivan O, Washko, George R, O'Connor, George T, Schwartz, David A

“…Variants in the gene encoding mucin 5B ( MUC5B ) have been associated with interstitial fibrosis. This study shows a relationship between the presence of the…”
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Short-Term Exposure to Air Pollution and Lung Function in the Framingham Heart Study by RICE, Mary B, LJUNGMAN, Petter L, WILKER, Elissa H, GOLD, Diane R, SCHWARTZ, Joel D, KOUTRAKIS, Petros, WASHKO, George R, O'CONNOR, George T, MITTLEMAN, Murray A

“…Short-term exposure to ambient air pollution has been associated with lower lung function. Few studies have examined whether these associations are detectable…”
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Serum IL-6: A biomarker in childhood asthma? by Jackson, Daniel J., Bacharier, Leonard B., Calatroni, Agustin, Gill, Michelle A., Hu, Jack, Liu, Andrew H., Wheatley, Lisa M., Gern, James E., Gruchalla, Rebecca S., Khurana Hershey, Gurjit K., Kattan, Meyer, Kercsmar, Carolyn M., Kim, Haejin, O’Connor, George T., Patel, Shilpa, Pongracic, Jacqueline A., Wood, Robert A., Busse, William W.

“…Serum IL-6 was associated with asthma exacerbation risk but not with symptoms or lung function in urban children; further studies to evaluate the role of IL-6…”
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Association of Nonobstructive Chronic Bronchitis With Respiratory Health Outcomes in Adults by Balte, Pallavi P, Chaves, Paulo H M, Couper, David J, Enright, Paul, Jacobs, Jr, David R, Kalhan, Ravi, Kronmal, Richard A, Loehr, Laura R, London, Stephanie J, Newman, Anne B, O'Connor, George T, Schwartz, Joseph E, Smith, Benjamin M, Smith, Lewis J, White, Wendy B, Yende, Sachin, Oelsner, Elizabeth C

“…Chronic bronchitis has been associated with cigarette smoking as well as with e-cigarette use among young adults, but the association of chronic bronchitis in…”
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Endotype of allergic asthma with airway obstruction in urban children by Altman, Matthew C., Calatroni, Agustin, Ramratnam, Sima, Jackson, Daniel J., Presnell, Scott, Rosasco, Mario G., Gergen, Peter J., Bacharier, Leonard B., O’Connor, George T., Sandel, Megan T., Kattan, Meyer, Wood, Robert A., Visness, Cynthia M., Gern, James E.

“…Black and Hispanic children growing up in disadvantaged urban neighborhoods have the highest rates of asthma and related morbidity in the United States. This…”
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Diet during Pregnancy and Infancy and the Infant Intestinal Microbiome by Savage, Jessica H., Lee-Sarwar, Kathleen A., Sordillo, Joanne E., Lange, Nancy E., Zhou, Yanjiao, O'Connor, George T., Sandel, Megan, Bacharier, Leonard B., Zeiger, Robert, Sodergren, Erica, Weinstock, George M., Gold, Diane R., Weiss, Scott T., Litonjua, Augusto A.

“…To determine the association between diet during pregnancy and infancy, including breastfeeding vs formula feeding, solid food introduction, and the infant…”
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The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality by Sanders, Jason L, Putman, Rachel K, Dupuis, Josée, Xu, Hanfei, Murabito, Joanne M, Araki, Tetsuro, Nishino, Mizuki, Benjamin, Emelia J, Levy, Daniel, Ramachandran, Vasan S, Washko, George R, Curtis, Jeffrey L, Freeman, Christine M, Bowler, Russell P, Hatabu, Hiroto, O'Connor, George T, Hunninghake, Gary M

“…The association between aging and idiopathic pulmonary fibrosis has been established. The associations between aging-related biomarkers and interstitial lung…”
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Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children by Altman, Matthew C., Flynn, Kaitlin, Rosasco, Mario G., Dapas, Matthew, Kattan, Meyer, Lovinsky-Desir, Stephanie, O’Connor, George T., Gill, Michelle A., Gruchalla, Rebecca S., Liu, Andrew H., Pongracic, Jacqueline A., Khurana Hershey, Gurjit K., Zoratti, Edward M., Teach, Stephen J., Rastrogi, Deepa, Wood, Robert A., Bacharier, Leonard B., LeBeau, Petra, Gergen, Peter J., Togias, Alkis, Busse, William W., Presnell, Scott, Gern, James E., Ober, Carole, Jackson, Daniel J.

“…Mucus plugging can worsen asthma control, lead to reduced lung function and fatal exacerbations. MUC5AC is the secretory mucin implicated in mucus plugging,…”
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