Search Results - "O’Connell, P Ronan"

The abundance of Akkermansia muciniphila and its relationship with sulphated colonic mucins in health and ulcerative colitis by Earley, Helen, Lennon, Grainne, Balfe, Áine, Coffey, J. Calvin, Winter, Desmond C., O’Connell, P. Ronan

“…Akkermansia muciniphila utilises colonic mucin as its substrate. Abundance is reduced in ulcerative colitis (UC), as is the relative proportion of sulphated…”
Get full text

So, You Want to be a Surgeon? by O’Connell, P. Ronan

Get full text

The Middle Compartment: Keystone or Cul De Sac? by O’Connell, P. Ronan

Get full text

Transanal Endoscopic Microsurgery Versus Standard Transanal Excision for the Removal of Rectal Neoplasms: A Systematic Review and Meta-analysis by Clancy, Cillian, Burke, John P, Albert, Mathew R, O’Connell, P Ronan, Winter, Desmond C

“…BACKGROUND:Transanal endoscopic microsurgery is the intraluminal excision of rectal lesions with the use of instrumentation to maintain a stable pneumorectum,…”
Get full text

The international anorectal physiology working group (IAPWG) recommendations: Standardized testing protocol and the London classification for disorders of anorectal function by Carrington, Emma V., Heinrich, Henriette, Knowles, Charles H., Fox, Mark, Rao, Satish, Altomare, Donato F., Bharucha, Adil E., Burgell, Rebecca, Chey, William D., Chiarioni, Guiseppe, Dinning, Philip, Emmanuel, Anton, Farouk, Ridzuan, Felt‐Bersma, Richelle J. F., Jung, Kee Wook, Lembo, Anthony, Malcolm, Allison, Mittal, Ravinder K., Mion, Franҫois, Myung, Seung‐Jae, O’Connell, P. Ronan, Pehl, Christian, Remes‐Troche, Jose María, Reveille, R. Matthew, Vaizey, Carolynne J., Vitton, Veronique, Whitehead, William E., Wong, Reuben K., Scott, S. Mark

“…Background This manuscript summarizes consensus reached by the International Anorectal Physiology Working Group (IAPWG) for the performance, terminology used,…”
Get full text

Desulfovibrio Bacterial Species Are Increased in Ulcerative Colitis by Rowan, Fiachra, Docherty, Neil G, Murphy, Madeline, Murphy, Brendan, Coffey, John Calvin, O‘Connell, P. Ronan

“…BACKGROUND:Debate persists regarding the role of Desulfovibrio subspecies in ulcerative colitis. Combined microscopic and molecular techniques enable this…”
Get full text

A Preliminary Study Examining the Binding Capacity of Akkermansia muciniphila and Desulfovibrio spp., to Colonic Mucin in Health and Ulcerative Colitis by Earley, Helen, Lennon, Grainne, Balfe, Aine, Kilcoyne, Michelle, Clyne, Marguerite, Joshi, Lokesh, Carrington, Stephen, Martin, Sean T, Coffey, J Calvin, Winter, Desmond C, O'Connell, P Ronan

“…Akkermansia muciniphila and Desulfovibrio spp. are commensal microbes colonising the mucus gel layer of the colon. Both species have the capacity to utilise…”
Get full text

Tumor Budding and PDC Grade Are Stage Independent Predictors of Clinical Outcome in Mismatch Repair Deficient Colorectal Cancer by Ryan, Éanna, Khaw, Yi Ling, Creavin, Ben, Geraghty, Robert, Ryan, Elizabeth J, Gibbons, David, Hanly, Ann, Martin, Sean T, O’Connell, P Ronan, Winter, Desmond C, Sheahan, Kieran

“…Mismatch repair deficient (dMMR) colorectal cancer (CRC) despite its association with poor histologic grade often has improved prognosis compared with MMR…”
Get full text

A Meta-Analysis of Surgical Morbidity and Recurrence After Laparoscopic and Open Repair of Primary Unilateral Inguinal Hernia by O'REILLY, Elma A, BURKE, John P, O'CONNELL, P. Ronan

“…Laparoscopic inguinal hernia repair (LIHR), using a transabdominal preperitoneal (TAPP) or totally extraperitoneal (TEP) technique, is an alternative to…”
Get full text

The Relationship Between Cortical Activation in Response to Anorectal Stimuli and Continence Behavior in Freely Behaving Rats Before and After Application of Sacral Nerve Stimulation by Evers, Judith, O’Connell, P. Ronan, Jones, James F.X.

“…Changes in anorectal sensation have been reported in patients with fecal incontinence, and there is limited evidence that sacral nerve stimulation can restore…”
Get full text

Percutaneous tibial nerve stimulation versus sham electrical stimulation for the treatment of faecal incontinence in adults (CONFIDeNT): a double-blind, multicentre, pragmatic, parallel-group, randomised controlled trial by Knowles, Charles H, Prof, Horrocks, Emma J, MBBS, Bremner, Stephen A, PhD, Stevens, Natasha, MSc, Norton, Christine, Prof, O'Connell, P Ronan, Prof, Eldridge, Sandra, Prof

“…Summary Background Percutaneous tibial nerve stimulation (PTNS) is a new ambulatory therapy for faecal incontinence. Data from case series suggest it has…”
Get full text

Colonisation of the colonic mucus gel layer with butyrogenic and hydrogenotropic bacteria in health and ulcerative colitis by Earley, Helen, Lennon, Grainne, Coffey, J. Calvin, Winter, Desmond C., O’Connell, P. Ronan

“…Butyrate is the primary energy source for colonocytes and is essential for mucosal integrity and repair. Butyrate deficiency as a result of colonic dysbiosis…”
Get full text

Needs Assessment for Treatment of Fecal Incontinence by O’Connell, P Ronan

Get full text

Career needs Assessment for Early Career Academic Surgeons using a Modified Accelerated Delphi Process by Fleming, Christina A., Augustinus, Simone, Lemmers, Daan H.L., López- López, Victor, Nitschke, Christine, Farges, Olivier, Salminen, Paulina, O’Connell, P. Ronan, Campos, Ricardo Robles, Caiazzo, Robert

“…Over the past two decades physicians wellbeing has become a topic of interest. It is currently unclear what the currents needs are of early career academic…”
Get full text

Prognostic significance of tumor budding in rectal cancer biopsies before neoadjuvant therapy by Rogers, Ailín C, Gibbons, David, Hanly, Ann M, Hyland, John MP, O'Connell, P Ronan, Winter, Desmond C, Sheahan, Kieran

“…Tumor budding is an increasingly important prognostic feature for pathologists to recognize. The aim of this study was to correlate intra-tumoral budding in…”
Get full text

Chronic constipation in adults: Contemporary perspectives and clinical challenges. 2: Conservative, behavioural, medical and surgical treatment by Corsetti, Maura, Brown, Steven, Chiarioni, Giuseppe, Dimidi, Eirini, Dudding, Thomas, Emmanuel, Anton, Fox, Mark, Ford, Alexander C., Giordano, Pasquale, Grossi, Ugo, Henderson, Michelle, Knowles, Charles H., O’Connell, P. Ronan, Quigley, Eamonn M. M., Simren, Magnus, Spiller, Robin, Whelan, Kevin, Whitehead, William E., Williams, Andrew B., Scott, S. Mark

“…Background Chronic constipation is a prevalent disorder that affects quality of life of patients and consumes resources in healthcare systems worldwide. In…”
Get full text

European Society of Coloproctology guidance on the use of mesh in the pelvis in colorectal surgery by Maeda, Yasuko, Espin‐Basany, Eloy, Gorissen, Kim, Kim, Mia, Lehur, Paul‐Antoine, Lundby, Lilli, Negoi, Ionut, Norcic, Gregor, O’Connell, P. Ronan, Rautio, Tero, Geluwe, Bart, Ramshorst, Gabrielle H., Warwick, Andrea, Vaizey, Carolynne J.

“…This is a comprehensive and rigorous review of currently available data on the use of mesh in the pelvis in colorectal surgery. This guideline outlines the…”
Get full text

Systematic Review of Animal Models Used in Research of Origins and Treatments of Fecal Incontinence by Evers, Judith, Jones, James F X, O’Connell, P Ronan

“…BACKGROUND:Fecal incontinence is a common disorder, but its pathophysiology is not completely understood. OBJECTIVE:The aim of this review is to present animal…”
Get full text

A Comparative Study of Short- and Medium-term Outcomes Comparing Emergent Surgery and Stenting as a Bridge to Surgery in Patients With Acute Malignant Colonic Obstruction by Kavanagh, Dara O, Nolan, Blathnaid, Judge, Ciaran, Hyland, John M P, Mulcahy, Hugh E, O’Connell, P Ronan, Winter, Des C, Doherty, Glen A

“…BACKGROUND:The use of self-expanding metal stents as a bridge to surgery in the setting of malignant colorectal obstruction has been advocated as an acceptable…”
Get full text

Fibrogenesis in Crohn's Disease by BURKE, John P, MULSOW, Jurgen J, O'KEANE, Conor, DOCHERTY, Neil G, WATSON, R. William G, RONAN O'CONNELL, P

“…Over one-third of patients with Crohn's disease (CD) will develop an intestinal stricture and the great majority of these will require at least one surgical…”
Get full text