Search Results - "O’Connell, C"

‘Trophic’ and ‘source’ amino acids in trophic estimation: a likely metabolic explanation by O’Connell, T. C.

“…Amino acid nitrogen isotopic analysis is a relatively new method for estimating trophic position. It uses the isotopic difference between an individual’s…”
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Variability in donor leukocyte counts confound the use of common RNA sequencing data normalization strategies in transcriptomic biomarker studies performed with whole blood by O’Connell, Grant C.

“…Gene expression data generated from whole blood via next generation sequencing is frequently used in studies aimed at identifying mRNA-based biomarker panels…”
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Role of direct oral anticoagulants in the treatment of cancer‐associated venous thromboembolism: guidance from the SSC of the ISTH by Khorana, A. A., Noble, S., Lee, A. Y. Y., Soff, G., Meyer, G., O'Connell, C., Carrier, M.

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International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 1. Fractures and luxations by Bourguignon, Cecilia, Cohenca, Nestor, Lauridsen, Eva, Flores, Marie Therese, O'Connell, Anne C., Day, Peter F., Tsilingaridis, Georgios, Abbott, Paul V., Fouad, Ashraf F., Hicks, Lamar, Andreasen, Jens Ove, Cehreli, Zafer C., Harlamb, Stephen, Kahler, Bill, Oginni, Adeleke, Semper, Marc, Levin, Liran

“…Traumatic dental injuries (TDIs) of permanent teeth occur frequently in children and young adults. Crown fractures and luxations of these teeth are the most…”
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The diet-body offset in human nitrogen isotopic values: A controlled dietary study by O'Connell, T.C., Kneale, C.J., Tasevska, N., Kuhnle, G.G.C.

“…The “trophic level enrichment” between diet and body results in an overall increase in nitrogen isotopic values as the food chain is ascended. Quantifying the…”
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Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair by Svendsen, Jennifer M., Smogorzewska, Agata, Sowa, Mathew E., O'Connell, Brenda C., Gygi, Steven P., Elledge, Stephen J., Harper, J. Wade

“…Structure-specific endonucleases mediate cleavage of DNA structures formed during repair of collapsed replication forks and double-strand breaks (DSBs). Here,…”
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International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 3. Injuries in the primary dentition by Day, Peter F., Flores, Marie Therese, O'Connell, Anne C., Abbott, Paul V., Tsilingaridis, Georgios, Fouad, Ashraf F., Cohenca, Nestor, Lauridsen, Eva, Bourguignon, Cecilia, Hicks, Lamar, Andreasen, Jens Ove, Cehreli, Zafer C., Harlamb, Stephen, Kahler, Bill, Oginni, Adeleke, Semper, Marc, Levin, Liran

“…Traumatic injuries to the primary dentition present special problems that often require far different management when compared to that used for the permanent…”
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Regulation of spatially restricted gene expression: linking RNA localization and phase separation by O'Connell, Liam C, Mowry, Kimberly L

“…Subcellular restriction of gene expression is crucial to the functioning of a wide variety of cell types. The cellular machinery driving spatially restricted…”
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Ancient Hybridization and an Irish Origin for the Modern Polar Bear Matriline by Edwards, Ceiridwen J., Suchard, Marc A., Lemey, Philippe, Welch, John J., Barnes, Ian, Fulton, Tara L., Barnett, Ross, O'Connell, Tamsin C., Coxon, Peter, Monaghan, Nigel, Valdiosera, Cristina E., Lorenzen, Eline D., Willerslev, Eske, Baryshnikov, Gennady F., Rambaut, Andrew, Thomas, Mark G., Bradley, Daniel G., Shapiro, Beth

“…Polar bears (Ursus maritimus) are among those species most susceptible to the rapidly changing arctic climate, and their survival is of global concern. Despite…”
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Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkers by O'Connell, Grant C., Smothers, Christine G., Winkelman, Chris

“…Detection of brain-specific miRNAs in the peripheral blood could serve as a surrogate marker of traumatic brain injury (TBI). Here, we systematically…”
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Monocyte-lymphocyte cross-communication via soluble CD163 directly links innate immune system activation and adaptive immune system suppression following ischemic stroke by O’Connell, Grant C., Tennant, Connie S., Lucke-Wold, Noelle, Kabbani, Yasser, Tarabishy, Abdul R., Chantler, Paul D., Barr, Taura L.

“…CD163 is a scavenger receptor expressed on innate immune cell populations which can be shed from the plasma membrane via the metalloprotease ADAM17 to generate…”
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Peripheral blood AKAP7 expression as an early marker for lymphocyte-mediated post-stroke blood brain barrier disruption by O’Connell, Grant C., Treadway, Madison B., Petrone, Ashley B., Tennant, Connie S., Lucke-Wold, Noelle, Chantler, Paul D., Barr, Taura L.

“…Our group recently identified 16 genes whose peripheral blood expression levels are differentially regulated in acute ischemic stroke. The purpose of this…”
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Dataset including whole blood gene expression profiles and matched leukocyte counts with utility for benchmarking cellular deconvolution pipelines by O'Connell, Grant C

“…Cellular deconvolution is a valuable computational process that can infer the cellular composition of heterogeneous tissue samples from bulk RNA-sequencing…”
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One Atom Makes All the Difference: Getting a Foot in the Door between SOS1 and KRAS by Ramharter, Juergen, Kessler, Dirk, Ettmayer, Peter, Hofmann, Marco H, Gerstberger, Thomas, Gmachl, Michael, Wunberg, Tobias, Kofink, Christiane, Sanderson, Michael, Arnhof, Heribert, Bader, Gerd, Rumpel, Klaus, Zöphel, Andreas, Schnitzer, Renate, Böttcher, Jark, O’Connell, Jonathan C, Mendes, Rachel L, Richard, David, Pototschnig, Nikolai, Weiner, Irene, Hela, Wolfgang, Hauer, Katja, Haering, Daniela, Lamarre, Lyne, Wolkerstorfer, Bernhard, Salamon, Christian, Werni, Patrick, Munico-Martinez, Silvia, Meyer, Reiner, Kennedy, Matthew D, Kraut, Norbert, McConnell, Darryl B

“…KRAS, the most common oncogenic driver in human cancers, is controlled and signals primarily through protein–protein interactions (PPIs). The interaction…”
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Regiochemical Switching in Ir-Catalyzed C–H Borylation by Altering Ligand Loadings of N,B-Type Diboron Species by O’Connell, Alex C., Mansour, Pauline A., Maleczka, Robert E., Smith, Milton R.

“…Traditional reaction conditions in Ir-catalyzed C–H borylation consist of a 2:1 ligand to Ir metal ratio, affording C­(sp2)–H borylation at the least…”
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Animal movement on the hoof and on the cart and its implications for understanding exchange within the Indus Civilisation by Petrie, C. A., Lightfoot, E., Jones, P. J., Walker, J. R., Valentine, B. T., Krigbaum, J., le Roux, P., Joglekar, P. P., Shinde, V., Singh, R. N., O’Connell, T. C.

“…Movement of resources was essential to the survival and success of early complex societies. The sources and destinations of goods and the means of…”
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Model matters: Differential outcomes in traumatic optic neuropathy pathophysiology between blunt and blast-wave mediated head injuries by Hetzer, S M, O'Connell, C, Lallo, V, Robson, M, Evanson, N K

“…Over 3 million people in the United States live with long-term disability because of a traumatic brain injury (TBI). The purpose of this study was to…”
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Use of high-sensitivity digital ELISA improves the diagnostic performance of circulating brain-specific proteins for detection of traumatic brain injury during triage by O'Connell, Grant C., Alder, Megan L., Smothers, Christine G., Still, Carolyn H., Webel, Allison R., Moore, Shirley M.

“…Background: Historically, limited sensitivity associated with traditional immunoassay methods has prevented the use of brain-specific proteins as blood…”
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Comment on “Ecological niche of Neanderthals from Spy Cave revealed by nitrogen isotopes of individual amino acids in collagen” [J. Hum. Evol. 93 (2016) 82–90] by O'Connell, Tamsin C., Collins, Matthew J.

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Risk of recurrent venous thromboembolism and major hemorrhage in cancer‐associated incidental pulmonary embolism among treated and untreated patients: a pooled analysis of 926 patients by Hulle, T., Exter, P. L., Planquette, B., Meyer, G., Soler, S., Monreal, M., Jiménez, D., Portillo, A. K., O'Connell, C., Liebman, H. A., Shteinberg, M., Adir, Y., Tiseo, M., Bersanelli, M., Abdel‐Razeq, H. N., Mansour, A. H., Donnelly, O. G., Radhakrishna, G., Ramasamy, S., Bozas, G., Maraveyas, A., Shinagare, A. B., Hatabu, H., Nishino, M., Huisman, M. V., Klok, F. A.

“…Essentials We performed a pooled analysis of 926 patients with cancer‐associated incidental pulmonary embolism (IPE). Vitamin K antagonists (VKA) are…”
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