Search Results - "O’Callaghan, S."

The role of inflammation in the pathogenesis of non-small cell lung cancer by O'Callaghan, Dermot S, O'Donnell, Dearbhaile, O'Connell, Finbarr, O'Byrne, Kenneth J

“…The link between chronic immune activation and tumorigenesis is well established. Compelling evidence has accumulated that histologic assessment of…”
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OA4‐AM23‐SN‐19 | Transfusion‐Transmitted Babesiosis Reported to Food and Drug Administration Before and after Implementation of the Final Guidance, 2017–2022 by Eder, A., O'Callaghan, S., Kumar, S.

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Pulmonary Arterial Hypertension in Patients Treated by Dasatinib by MONTANI, David, BERGOT, Emmanuel, POUBEAU, Patrice, GIRERD, Barbara, NATALI, Delphine, GUIGNABERT, Christophe, PERROS, Frederic, O'CALLAGHAN, Dermot S, JAÏS, Xavier, TUBERT-BITTER, Pascale, ZALCMAN, Gerard, SITBON, Olivier, GÜNTHER, Sven, SIMONNEAU, Gerald, HUMBERT, Marc, SAVALE, Laurent, BERGERON, Anne, BOURDIN, Arnaud, BOUVAIST, Helene, CANUET, Matthieu, PISON, Christophe, MACRO, Margareth

“…The French pulmonary hypertension (PH) registry allows the survey of epidemiological trends. Isolated cases of precapillary PH have been reported in patients…”
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Is orthostatic hypotension more common in individuals with atrial fibrillation?-Findings from The Irish Longitudinal Study on Ageing (TILDA) by McNicholas, T, Tobin, K, O'Callaghan, S, Kenny, R A

“…atrial fibrillation (AF) and orthostatic hypotension (OH) share common risk factors such as age, hypertension and cardiovascular (CV) disease. The autonomic…”
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A meta-analysis of the relationship between subjective sleep and depressive symptoms in adolescence by O'Callaghan, Victoria S., Couvy-Duchesne, Baptiste, Strike, Lachlan T., McMahon, Katie L., Byrne, Enda M., Wright, Margaret J.

“…Adolescence is a risk period for the development of mental illness, as well as a time for pronounced change in sleep behaviour. While prior studies, including…”
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Generation of Tosyl Azide in Continuous Flow Using an Azide Resin, and Telescoping with Diazo Transfer and Rhodium Acetate-Catalyzed O–H Insertion by O’Mahony, Rosella M, Lynch, Denis, O’Callaghan, Katie S, Collins, Stuart G, Maguire, Anita R

“…Generation of tosyl azide 12 in acetonitrile in flow under water-free conditions using an azide resin and its use in diazo transfer to a series of aryl…”
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Clinical outcomes of pulmonary arterial hypertension in patients carrying an ACVRL1 (ALK1) mutation by Girerd, Barbara, Montani, David, Coulet, Florence, Sztrymf, Benjamin, Yaici, Azzeddine, Jaïs, Xavier, Tregouet, David, Reis, Abilio, Drouin-Garraud, Valérie, Fraisse, Alain, Sitbon, Olivier, O'Callaghan, Dermot S, Simonneau, Gérald, Soubrier, Florent, Humbert, Marc

“…Activin A receptor type II-like kinase-1 (ACVRL1, also known as ALK1) mutation is a cause of hereditary hemorrhagic telangiectasia (HHT) and/or heritable…”
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Efficacy, safety and pharmacokinetics of bosentan in portopulmonary hypertension by SAVALE, Laurent, MAGNIER, Romain, LE PAVEC, Jerome, JAÏS, Xavier, MONTANI, David, O'CALIAGHAN, Dermot S, HUMBERT, Marc, DINGEMANSE, Jasper, SIMONNEAU, Gérald, SITBON, Olivier

“…Data on treatment of patients with portopulmonary hypertension (PoPH) are limited, as they are usually excluded from randomised controlled trials with…”
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A Proof-of-Concept, Randomized, Controlled Trial of Omalizumab in Patients With Severe, Difficult-to-Control, Nonatopic Asthma by Garcia, Gilles, MD, PhD, Magnan, Antoine, MD, PhD, Chiron, Raphaël, MD, Contin-Bordes, Cécile, MD, PhD, Berger, Patrick, MD, PhD, Taillé, Camille, MD, PhD, Devouassoux, Gilles, MD, PhD, de Blay, Frédéric, MD, PhD, Couderc, Louis-Jean, MD, PhD, Didier, Alain, MD, PhD, O'Callaghan, Dermot S., MD, Girodet, Pierre-Olivier, MD, PhD, Bourdeix, Isabelle, PhD, Le Gros, Vincent, MD, Humbert, Marc, MD, PhD

“…Background While up to 50% of patients with severe asthma have no evidence of allergy, IgE has been linked to asthma, irrespective of atopic status…”
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A critical analysis of survival in pulmonary arterial hypertension by O'Callaghan, Dermot S, Humbert, Marc

“…Pulmonary arterial hypertension (PAH) is a rare disease characterised by a progressive increase in pulmonary vascular resistance, leading to right heart…”
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Usefulness of first-line combination therapy with epoprostenol and bosentan in pulmonary arterial hypertension: An observational study by Kemp, Kristina, MD, Savale, Laurent, MD, PhD, O'Callaghan, Dermot S., MD, Jaïs, Xavier, MD, Montani, David, MD, PhD, Humbert, Marc, MD, PhD, Simonneau, Gérald, MD, Sitbon, Olivier, MD, PhD

“…Background Recent guidelines have proposed first-line combination therapy as a potential strategy for the treatment of functional class IV pulmonary arterial…”
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Characterization of pulmonary arterial hypertension patients walking more than 450 m in 6 min at diagnosis by Degano, Bruno, Sitbon, Olivier, Savale, Laurent, Garcia, Gilles, O'Callaghan, Dermot S, Jaïs, Xavier, Humbert, Marc, Simonneau, Gérald

“…At diagnosis of pulmonary arterial hypertension (PAH), some patients are considered to have a "near-normal" 6-min walk distance (6MWD) (ie, > 450 m). Because…”
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Current management approaches to portopulmonary hypertension by Savale, L, O'Callaghan, D S, Magnier, R, Le Pavec, J, Hervé, P, Jaïs, X, Seferian, A, Humbert, M, Simonneau, G, Sitbon, O

“…Portopulmonary hypertension (PoPH) is a rare but life-threatening complication of portal hypertension that is characterised by proliferative changes in the…”
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Endothelin receptor antagonists for the treatment of pulmonary arterial hypertension by O'Callaghan, Dermot S, Savale, Laurent, Yaïci, Azzedine, Natali, Delphine, Jaïs, Xavier, Parent, Florence, Montani, David, Humbert, Marc, Simonneau, Gérald, Sitbon, Olivier

“…Endothelin is a key mediator in the pathophysiology of pulmonary arterial hypertension (PAH). Its effects are mediated through the activation of two associated…”
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The association between resting and mild-to-moderate exercise pulmonary artery pressure by WHYTE, K, HOETTE, S, SITBON, O, SIMONNEAU, G, HUMBERT, M, CHEMLA, D, HERVE, P, MONTANI, D, JAÏS, X, PARENT, F, SAVALE, L, NATALI, D, O'CALLAGHAN, D. S, GARCIA, G

“…The mean pulmonary artery pressure (P(pa)) achieved on mild-to-moderate exercise is age related and its haemodynamic correlates remain to be documented in…”
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Implementing the ESC/ERS pulmonary hypertension guidelines: real-life cases from a national referral centre by Montani, D, O'Callaghan, D. S, Jais, X, Savale, L, Natali, D, Redzepi, A, Hoette, S, Parent, F, Sitbon, O, Simonneau, G, Humbert, M

“…* Univ Paris-Sud, Faculté de médecine, Kremlin-Bicêtre, # AP-HP, Centre National de Référence de l'Hypertension Pulmonaire Sévère, Service de Pneumologie et…”
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Tramadol as adjunct to psoas compartment block with levobupivacaine 0.5%: a randomized double-blinded study by Mannion, S., O’Callaghan, S., Murphy, D.B., Shorten, G.D.

“…Tramadol has been administered peripherally to prolong analgesia after brachial plexus and neuraxial blocks. Our aim was to evaluate the systemic and…”
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A Hemodynamic Study of Pulmonary Hypertension in Sickle Cell Disease by Parent, Florence, Bachir, Dora, Inamo, Jocelyn, Lionnet, François, Driss, Françoise, Loko, Gylna, Habibi, Anoosha, Bennani, Soumiya, Savale, Laurent, Adnot, Serge, Maitre, Bernard, Yaïci, Azzedine, Hajji, Leila, O'Callaghan, Dermot S, Clerson, Pierre, Girot, Robert, Galacteros, Frederic, Simonneau, Gerald

“…Patients with sickle cell disease underwent ECG with assessment of tricuspid valve regurgitant jet velocity (TRJV) to screen for pulmonary hypertension,…”
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Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension by Humbert, M, Sitbon, O, Yaïci, A, Montani, D, O'Callaghan, D S, Jaïs, X, Parent, F, Savale, L, Natali, D, Günther, S, Chaouat, A, Chabot, F, Cordier, J-F, Habib, G, Gressin, V, Jing, Z-C, Souza, R, Simonneau, G

“…Pulmonary arterial hypertension (PAH) is a progressive, fatal disease. We studied 674 consecutive adult patients who were prospectively enrolled in the French…”
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Tumour islet Foxp3+ T-cell infiltration predicts poor outcome in nonsmall cell lung cancer by O'Callaghan, Dermot S, Rexhepaj, Elton, Gately, Kathy, Coate, Linda, Delaney, David, O'Donnell, Dearbhaile M, Kay, Elaine, O'Connell, Finbarr, Gallagher, William M, O'Byrne, Kenneth J

“…The impact of host immunity on outcome in nonsmall cell lung cancer (NSCLC) is controversial. We examined the relationship between lymphoid infiltration…”
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