Search Results - "O’Byrne, S M"
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Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
Published in Gut (01-01-2005)“…Background: Hepatic stellate cells (HSCs) are a major fibrogenic cell type that contributes to collagen accumulation during chronic liver disease. With…”
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Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea
Published in European heart journal (01-03-2012)“…Delayed lipoprotein clearance is associated with atherosclerosis. This study examined whether chronic intermittent hypoxia (CIH), a hallmark of obstructive…”
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Retinol-Binding Protein-Deficient Mice: Biochemical Basis for Impaired Vision
Published in Biochemistry (Easton) (24-12-2002)“…We reported previously that mice lacking plasma retinol-binding protein (RBP) are phenotypically normal except that they display impaired vision at the time of…”
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Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis
Published in Gut (01-09-2011)“…Hepatic stellate cells (HSCs) contain a number of bioactive metabolites or their precursors including retinoids in their characteristic lipid droplets. The…”
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Retinoid Absorption and Storage Is Impaired in Mice Lacking Lecithin:Retinol Acyltransferase (LRAT)
Published in The Journal of biological chemistry (21-10-2005)“…Lecithin:retinol acyltransferase (LRAT) is believed to be the predominant if not the sole enzyme in the body responsible for the physiologic esterification of…”
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Serum retinol-binding protein concentration and its association with components of the uremic metabolic syndrome in nondiabetic patients with chronic kidney disease stage 5
Published in American journal of nephrology (01-01-2009)“…Chronic kidney disease (CKD) is associated with insulin resistance also in the absence of overt diabetes mellitus. The liver-derived transport protein…”
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Mechanism of Action of Bimatoprost, Latanoprost, and Travoprost in Healthy Subjects
Published in Ophthalmology (Rochester, Minn.) (01-05-2008)“…Purpose To study the effects of 3 prostaglandin analogs, bimatoprost, latanoprost, and travoprost, on aqueous dynamics in the same subjects and to compare…”
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