Search Results - "O’Brien, Christopher B."

Hepatotoxicity Secondary to Chemotherapy by Grigorian, Alla, O'Brien, Christopher B

“…The difficult problem faced by multiple generation of practicing physicians is determining the cause of abnormal liver function tests in cancer patients on…”
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Buprenorphine differentially alters breathing among four congenic mouse lines as a function of dose, sex, and leptin status by Glovak, Zachary T., Angel, Chelsea, O’Brien, Christopher B., Baghdoyan, Helen A., Lydic, Ralph

“…•Buprenorphine caused dose-dependent changes in breathing.•Buprenorphine differentially changed breathing among the four congenic mouse lines.•Leptin…”
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When is it safe to perform abdominal transplantation in patients with prior SARS‐CoV‐2 infection: A case series by Natori, Yoichiro, Anjan, Shweta, Martin, Eric F., Selvagi, Gennaro, Villavicencio, Aasith, Coro, Ana, Mendez‐Castaner, Lumen A., Mattiazzi, Adela, Pagan, Javier, Ortigosa‐Goggins, Mariella, Roth, David, Kupin, Warren, O’Brien, Christopher B., Arosemena, Leopoldo R., Ciancio, Gaetano, Burke, George W., Morsi, Mahmoud, Figueiro, Jose M., Chen, Linda, Tekin, Akin, Miyashiro, Rafael, Simkins, Jacques, Abbo, Lilian M., Vianna, Rodrigo M., Guerra, Giselle

“…Background The Coronavirus disease 2019(COVID‐19) pandemic has negatively impacted worldwide organ transplantation. However, there is limited information on…”
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Peginterferon alfa-2a (40 kilodaltons) and ribavirin in patients with chronic hepatitis C and normal aminotransferase levels by Zeuzem, Stefan, Diago, Moisés, Gane, Edward, Reddy, K. Rajender, Pockros, Paul, Prati, Daniele, Shiffman, Mitchell, Farci, Patrizia, Gitlin, Norman, O’Brien, Christopher B., Lamour, François, Lardelli, Pilar

“…Background & Aims: Patients with chronic hepatitis C and persistently normal alanine aminotransferase (ALT) levels have been routinely excluded from large…”
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Chemotherapy-Induced Hepatotoxicity by Thatishetty, Ameet V., MD, Agresti, Nicholas, MD, O'Brien, Christopher B., MD, AGAF, FRCMI

“…Most hepatotoxicity secondary to chemotherapy is idiosyncratic and, therefore, neither dose dependent nor predictable. Some chemotherapy is cleared by the…”
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Treatment of established recurrent hepatitis C in liver-transplant recipients with pegylated interferon-alfa-2b and ribavirin therapy by NEFF, Guy W, MONTALBANO, Marzia, NERY, Jose, DE MEDINA, Maria, TZAKIS, Andreas, SCHIFF, Eugene R, O'BRIEN, Christopher B, NISHIDA, Seigo, SAFDAR, Kamran, BEJARANO, Pablo A, KHALED, Amr S, RUIZ, Phillip, SLAPAK-GREEN, Gabriella, MEI LEE

“…The management issues of transplant patients with hepatitis C virus (HCV) are complex, and interferon therapy is often ineffective. We present data from a…”
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The Hospitalized Patient with Abnormal Liver Function Tests by O'Brien, Christopher B., MD, FACG

“…Evaluation of abnormal liver function tests (LFTs) in the hospitalized patient is typically more urgent than the outpatient setting. This process is best…”
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Opioids cause dissociated states of consciousness in C57BL/6J mice by O'Brien, Christopher B, Locklear, Clarence E, Glovak, Zachary T, Zebadúa Unzaga, Diana, Baghdoyan, Helen A, Lydic, Ralph

“…The electroencephalogram (EEG) provides an objective, neural correlate of consciousness. Opioid receptors modulate mammalian neuronal excitability, and this…”
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Is the Omicron variant truly less virulent in solid organ transplant recipients? by Anjan, Shweta, Khatri, Akshay, Viotti, Julia Bini, Cheung, Teresa, Garcia, Leopoldo A. Cordova, Simkins, Jacques, Loebe, Matthias, Phancao, Anita, O'Brien, Christopher B., Sinha, Neeraj, Ciancio, Gaetano, Vianna, Rodrigo M., Andrews, David, Abbo, Lilian M., Guerra, Giselle, Natori, Yoichiro

“…Solid organ transplant (SOT) recipients are at high risk for severe disease with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection…”
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Cell-Free DNA as a Surveillance Tool for Hepatocellular Carcinoma Patients after Liver Transplant by Manzi, Joao, Hoff, Camilla O, Ferreira, Raphaella, Glehn-Ponsirenas, Renata, Selvaggi, Gennaro, Tekin, Akin, O'Brien, Christopher B, Feun, Lynn, Vianna, Rodrigo, Abreu, Phillipe

“…The liver is the world's sixth most common primary tumor site, responsible for approximately 5% of all cancers and over 8% of cancer-related deaths…”
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Sa1073 Spontaneous Clearance of the Hepatitis C Virus in Liver Transplant Patients by Agresti, Nicholas, O'Brien, Christopher B

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Ursodeoxycholic acid for the treatment of primary sclerosing cholangitis: a 30-month pilot study by O'Brien, C B, Senior, J R, Arora-Mirchandani, R, Batta, A K, Salen, G

“…We investigated the effects of once-daily oral administration of 10 mg/kg ursodeoxycholic acid (generic name, ursodiol) on elevated serum enzyme activities,…”
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Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of Synthetic Preimplantation Factor in Autoimmune Hepatitis by O’Brien, Christopher B., Barnea, Eytan R., Martin, Paul, Levy, Cynthia, Sharabi, Eden, Bhamidimarri, Kalyan R., Martin, Eric, Arosemena, Leopold, Schiff, Eugene R.

“…Preimplantation factor (PIF) is an evolutionary conserved peptide secreted by viable embryos which promotes maternal tolerance without immune suppression…”
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Diagnostic Laparoscopic Liver Biopsy: A Single Center Experience by Jeffers, Lennox, Bollineni, Deepthi, O'Brien, Christopher B, Schiff, Eugene R, Martin, Paul

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255 Chronic Hepatitis B Genotype B or C E Antigen Positive Patients: Viral Suppression, HBeAg Loss and Seroconversion Rates Are Improved with Telbivudine Compared with Lamivudine - Results from a Pooled Analysis by O'Brien, Christopher B, Jia, Jidong, Zeldin, Gillian

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Outcomes in liver transplant recipients with hepatitis B virus: Resistance and recurrence patterns from a large transplant center over the last decade by Neff, Guy W., O'Brien, Christopher B., Nery, Jose, Shire, Norah, Montalbano, Marzia, Ruiz, Phillip, Nery, Ciao, Safdar, Kamran, De Medina, Maria, Tzakis, Andreas G., Schiff, Eugene R., Madariaga, Juan

“…Hepatitis B virus (HBV) recurrence following liver transplantation (LTx) has been controllable primarily with the use of hepatitis B immune globulin (HBIg) and…”
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Viral and metabolic factors influencing alanine aminotransferase activity in patients with chronic hepatitis C by Prati, Daniele, Shiffman, Mitchell L., Diago, Moisés, Gane, Edward, Rajender Reddy, K., Pockros, Paul, Farci, Patrizia, O'Brien, Christopher B., Lardelli, Pilar, Blotner, Steven, Zeuzem, Stefan

“…In chronic hepatitis C, disease progression and clinical manifestations are heterogenous. To clarify the role and interactions of viral and host factors in…”
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Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease by Neff, Guy W, O'Brien, Christopher B, Reddy, Rajender K., Bergasa, Nora V, Regev, Arie, Molina, Enrique, Amaro, Rafael, Rodriguez, Miguel J, Chase, VeEtta, Jeffers, Lennox, Schiff, Eugene

“…Pruritus due to cholestatic liver disease can be particularly difficult to manage and frequently is intractable to a variety of medical therapies. The aim of…”
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Factors that identify survival after liver retransplantation for allograft failure caused by recurrent hepatitis C infection by Neff, Guy W., O'Brien, Christopher B., Nery, Jose, Shire, Norah J., Nishida, Seigo, delaGarza, Julia, Montalbano, Marzia, Safdar, Kamran, Ruiz, Phillip, Rideman, Eric, Gascon, Jose A., Tzakis, Andreas G., Madariaga, Juan, Rudich, Steven M.

“…Hepatitis C virus (HCV) is becoming the most common indication for liver retransplantation (ReLTx). This study was a retrospective review of the medical…”
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M1885 Prevalence of Hepatic Steatosis Based on Ethnicity by Ghanta, Ravi, Czul, Frank, Carrion-Monsalve, Andres, Arosemena, Leopoldo, Garcia, Monica T, Bejarano, Pablo A, Jeffers, Lennox, O'Brien, Christopher B, Schiff, Eugene R, Martin, Paul

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