Search Results - "O’Brian, Mark R."

Perception and Homeostatic Control of Iron in the Rhizobia and Related Bacteria by O'Brian, Mark R

“…Iron is an essential nutrient, but it can also be toxic. Therefore, iron homeostasis must be strictly regulated. Transcriptional control of iron-dependent gene…”
Get full text

Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product by Dailey, Harry A, Dailey, Tamara A, Gerdes, Svetlana, Jahn, Dieter, Jahn, Martina, O'Brian, Mark R, Warren, Martin J

“…The advent of heme during evolution allowed organisms possessing this compound to safely and efficiently carry out a variety of chemical reactions that…”
Get full text

Synthetic Lethality of the bfr and mbfA Genes Reveals a Functional Relationship between Iron Storage and Iron Export in Managing Stress Responses in Bradyrhizobium japonicum by Sankari, Siva, O'Brian, Mark R

“…An mbfA mutant of Bradyrhizobium japonicum defective in iron export is sensitive to short term exposure to high levels iron or H2O2. Here, we found that the…”
Get full text

The Bradyrhizobium japonicum Ferrous Iron Transporter FeoAB Is Required for Ferric Iron Utilization in Free Living Aerobic Cells and for Symbiosis by Sankari, Siva, O'Brian, Mark R.

“…The bacterium Bradyrhizobium japonicum USDA110 does not synthesize siderophores for iron utilization in aerobic environments, and the mechanism of iron uptake…”
Get full text

Manganese is required for oxidative metabolism in unstressed Bradyrhizobium japonicum cells by Hohle, Thomas H., O'Brian, Mark R.

“…Summary Recent studies of Mn2+ transport mutants indicate that manganese is essential for unstressed growth in some bacterial species, but is required…”
Get full text

Control of bacterial iron homeostasis by manganese by Puri, Sumant, Hohle, Thomas H, O'Brian, Mark R

“…Perception and response to nutritional iron availability by bacteria are essential to control cellular iron homeostasis. The Irr protein from Bradyrhizobium…”
Get full text

Bacterial outer membrane channel for divalent metal ion acquisition by Hohle, Thomas H, Franck, William L, Stacey, Gary, O'Brian, Mark R

“…The prevailing model of bacterial membrane function predicts that the outer membrane is permeable to most small solutes because of pores with limited…”
Get full text

HmuP Is a Coactivator of Irr-Dependent Expression of Heme Utilization Genes in Bradyrhizobium japonicum by Escamilla-Hernandez, Rosalba, O'Brian, Mark R

“…Utilization of heme as an iron source by Bradyrhizobium japonicum involves induction of the outer membrane heme receptor gene hmuR and other genes within the…”
Get full text

The Bradyrhizobium japonicum frcB Gene Encodes a Diheme Ferric Reductase by SMALL, Sandra K, O'BRIAN, Mark R

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Transcriptional Control of the Bradyrhizobium japonicum irr Gene Requires Repression by Fur and Antirepression by Irr by Hohle, Thomas H., O'Brian, Mark R.

“…Bradyrhizobium japonicum Fur mediates manganese-responsive transcriptional control of the mntH gene independently of iron, but it also has been implicated in…”
Get full text

The hmuQ and hmuD Genes from Bradyrhizobium japonicum Encode Heme-Degrading Enzymes by PURI, Sumant, O'BRIAN, Mark R

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Bradyrhizobium japonicum HmuP is an RNA‐binding protein that positively controls hmuR operon expression by suppression of a negative regulatory RNA element in the 5′ untranslated region by Wu, Peipei, Ong, Alasteir, O'Brian, Mark R.

“…The hmuR operon encodes proteins for the uptake and utilization of heme as a nutritional iron source in Bradyrhizobium japonicum. The hmuR operon is…”
Get full text

The divalent metal ion exporter IhpABC is required to maintain iron homeostasis under low to moderate environmental iron conditions in the bacterium Bradyrhizobium japonicum by Zhang, Fengyue, O'Brian, Mark R.

“…Bacterial iron export mitigates high iron stress, but a role for it under lower iron conditions has not been established. MbfA is the high iron stress exporter…”
Get full text

Positive Control of Ferric Siderophore Receptor Gene Expression by the Irr Protein in Bradyrhizobium japonicum by Small, Sandra K, Puri, Sumant, Sangwan, Indu, O'Brian, Mark R

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

The Bradyrhizobium japonicum exporter ExsFGH is involved in efflux of ferric xenosiderophores from the periplasm by Ong, Alasteir, O'Brian, Mark R

“…The gram-negative bacterium Bradyrhizobium japonicum can take up structurally dissimilar ferric siderophores from the environment (xenosiderophores) to meet…”
Get full text

Bradyrhizobium japonicum senses iron through the status of haem to regulate iron homeostasis and metabolism by Yang, Jianhua, Sangwan, Indu, Lindemann, Andrea, Hauser, Felix, Hennecke, Hauke, Fischer, Hans‐Martin, O'Brian, Mark R.

“…Summary The Irr protein from the bacterium Bradyrhizobium japonicum is expressed under iron limitation to mediate iron control of haem biosynthesis. The…”
Get full text

Control of DegP-Dependent Degradation of c-Type Cytochromes by Heme and the Cytochrome c Maturation System in Escherichia coli by Tao Gao, Mark R. O'Brian

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

The Bradyrhizobium japonicum Irr Protein Is a Transcriptional Repressor with High-Affinity DNA-Binding Activity by Sangwan, Indu, Small, Sandra K., O'Brian, Mark R.

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Interaction between the Bacterial Iron Response Regulator and Ferrochelatase Mediates Genetic Control of Heme Biosynthesis by Qi, Zhenhao, O'Brian, Mark R

“…The heme biosynthetic pathway culminates with the insertion of iron into protoporphyrin catalyzed by ferrochelatase. The Bradyrhizobium japonicum iron response…”
Get full text

A new small regulatory protein, HmuP, modulates haemin acquisition in Sinorhizobium meliloti by Amarelle, Vanesa, Koziol, Uriel, Rosconi, Federico, Noya, Francisco, O'Brian, Mark R, Fabiano, Elena

“…Sinorhizobium meliloti has multiple systems for iron acquisition, including the use of haem as an iron source. Haem internalization involves the ShmR haem…”
Get full text