Search Results - "Oñate, Angel A"

The Role of the Flagellar Protein FlgJ in the Virulence of Brucella abortus by Coloma-Rivero, Roberto F, Gómez, Leonardo, Alvarez, Francisco, Saitz, Waleska, Del Canto, Felipe, Céspedes, Sandra, Vidal, Roberto, Oñate, Angel A

“…is a facultative intracellular pathogen that causes a zoonosis called brucellosis. This disease leads to abortion and infertility in cattle, and diverse…”
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Two centuries of vaccination: historical and conceptual approach and future perspectives by Montero, David A, Vidal, Roberto M, Velasco, Juliana, Carreño, Leandro J, Torres, Juan P, Benachi O, Manuel A, Tovar-Rosero, Yenifer-Yadira, Oñate, Angel A, O'Ryan, Miguel

“…Over the past two centuries, vaccines have been critical for the prevention of infectious diseases and are considered milestones in the medical and public…”
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Evaluation of the Humoral Response after Immunization with a Chimeric Subunit Vaccine against Shiga Toxin-Producing Escherichia coli in Pregnant Sows and Their Offspring by Vidal, Roberto M, Montero, David A, Bentancor, Adriana, Arellano, Carolina, Alvarez, Alhejandra, Cundon, Cecilia, Blanco Crivelli, Ximena, Del Canto, Felipe, Salazar, Juan C, Oñate, Angel A

“…Shiga toxin-producing (STEC) poses a significant public health risk due to its zoonotic potential and association with severe human diseases, such as…”
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Intranasal Immunization of Mice with Multiepitope Chimeric Vaccine Candidate Based on Conserved Autotransporters SigA, Pic and Sap, Confers Protection against Shigella flexneri by León, Yrvin, Zapata, Lionel, Molina, Raúl E., Okanovič, Gaj, Gómez, Leonardo A., Daza-Castro, Carla, Flores-Concha, Manuel, Reyes, José L., Oñate, Angel A.

“…Shigellosis is a diarrheal disease and the World Health Organization prompts the development of a vaccine against Shigella flexneri. The autotransporters SigA,…”
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A Zinc-Dependent Metalloproteinase of Brucella abortus Is Required in the Intracellular Adaptation of Macrophages by Gómez, Leonardo A, Alvarez, Francisco I, Molina, Raúl E, Soto-Shara, Rodrigo, Daza-Castro, Carla, Flores, Manuel R, León, Yrvin, Oñate, Angel A

“…is a pathogen that survives in macrophages. Several virulence factors participate in this process, including the open reading frame (ORF) BAB1_0270 codifying…”
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Immunogenicity and Protective Response Induced by Recombinant Plasmids Based on the BAB1_0267 and BAB1_0270 Open Reading Frames of Brucella abortus 2308 in BALB/c Mice by Gómez, Leonardo A, Alvarez, Francisco I, Fernández, Pablo A, Flores, Manuel R, Molina, Raúl E, Coloma, Roberto F, Oñate, Angel A

“…Immunogenicity induced by recombinant plasmids based on the BAB1_0267 and BAB1_0270 open reading frames (ORFs) of 2308 was evaluated. Bioinformatics analyses…”
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RNA Vaccine Based on Recombinant Semliki Forest Virus Particles Expressing the Cu,Zn Superoxide Dismutase Protein of Brucella abortus Induces Protective Immunity in BALB/c Mice by Oñate, Angel A, Donoso, Gabriel, Moraga-Cid, Gustavo, Folch, Hugo, Céspedes, Sandra, Andrews, Edilia

“…We constructed infectious but replication-deficient Semliki Forest virus (SFV) particles carrying recombinant RNA encoding Brucella abortus Cu,Zn superoxide…”
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Long Non-coding RNAs in the Regulation of the Immune Response and Trained Immunity by Flores-Concha, Manuel, Oñate, Ángel A.

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Unraveling the Role of the Zinc-Dependent Metalloproteinase/HTH-Xre Toxin/Antitoxin (TA) System of Brucella abortus in the Oxidative Stress Response: Insights into the Stress Response and Virulence by Gómez, Leonardo A, Molina, Raúl E, Soto, Rodrigo I, Flores, Manuel R, Coloma-Rivero, Roberto F, Montero, David A, Oñate, Ángel A

“…Toxin/antitoxin (TA) systems have been scarcely studied in , the causative agent of brucellosis, which is one of the most prevalent zoonotic diseases…”
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Vaccination with live Escherichia coli expressing Brucella abortus Cu/Zn superoxide dismutase protects mice against virulent B. abortus by Onate, A.A, Vemulapalli, R, Andrews, E, Schurig, G.G, Boyle, S, Folch, H

“…Vaccination of mice with Escherichia coli expressing Brucella Cu/Zn superoxide dismutase (SOD) [E. coli (pBSSOD)] induced a significant level of protection…”
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Brucella and Its Hidden Flagellar System by Coloma-Rivero, Roberto F, Flores-Concha, Manuel, Molina, Raúl E, Soto-Shara, Rodrigo, Cartes, Ángelo, Oñate, Ángel A

“…, a Gram-negative bacterium with a high infective capacity and a wide spectrum of hosts in the animal world, is found in terrestrial and marine mammals, as…”
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Characterization of Genomic Island 3 and Genetic Variability of Chilean Field Strains of Brucella abortus by CESPEDES, Sandra, SALGADO, Paulina, VALENZUELA, Patricio, VIDAL, Roberto, ONATE, Angel A

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A DNA Vaccine Encoding Cu,Zn Superoxide Dismutase of Brucella abortus Induces Protective Immunity in BALB/c Mice by ONATE, Angel A, CESPEDES, Sandra, CABRERA, Alex, RIVERS, Rodolfo, GONZALEZ, Andrés, MUNOZ, Carola, FOLCH, Hugo, ANDREWS, Edilia

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Intraspleen Delivery of a DNA Vaccine Coding for Superoxide Dismutase (SOD) of Brucella abortus Induces SOD-Specific CD4+ and CD8+ T Cells by MUNOZ-MONTESINO, Carola, ANDREWS, Edilia, RIVERS, Rodolfo, GONZALEZ-SMITH, Andrés, MORAGA-CID, Gustavo, FOLCH, Hugo, CESPEDES, Sandra, ONATE, Angel A

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Unraveling the Role of the Zinc-Dependent Metalloproteinase/HTH-Xre Toxin/Antitoxin System of IBrucella abortus/I in the Oxidative Stress Response: Insights into the Stress Response and Virulence by Gómez, Leonardo A, Molina, Raúl E, Soto, Rodrigo I, Flores, Manuel R, Coloma-Rivero, Roberto F, Montero, David A, Oñate, Ángel A

“…Toxin/antitoxin (TA) systems have been scarcely studied in Brucella abortus, the causative agent of brucellosis, which is one of the most prevalent zoonotic…”
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Semliki Forest virus that encodes a Brucella abortus IF3 protein protects BALB/c mice against infection by Cabrera, Alex C., Sáez, Darwin R., Andrews, Edilia M., Oñate, Angel A.

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Characterization of specific immune responses in cattle immunized with plasmid DNA construct and recombinant Semliki Forest virus particles encoding Cu,Zn superoxide dismutase (SOD) of Brucella abortus by Oñate, Angel A., Sáez, Darwin R., Guzmán, Ingrid I., Andrews, Edilia M., Cabrera, Alex C.

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Vaccination with Live Escherichia coli ExpressingBrucella abortus Cu/Zn Superoxide Dismutase Protects Mice against Virulent B. abortus by Angel A. Oñate, Ramesh Vemulapalli, Edilia Andrews, Gerhardt G. Schurig, Stephen Boyle, Hugo Folch

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An RNA vaccine based on recombinant semliki forest virus particles expressing the Cu,Zn superoxide dismutase protein of Brucella abortus induces protective immunity in BALBb/c mice by ONATE, Angel A, DONOSO, Gabriel, MORAGA-CID, Gustavo, FOLCH, Hugo, CESPEDES, Sandra, ANDREWS, Edilia

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