Search Results - "O, Chun Kwan"
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Detection of increased serum miR-122-5p and miR-455-3p levels before the clinical diagnosis of liver cancer in people with type 2 diabetes
Published in Scientific reports (09-12-2021)“…People with type 2 diabetes (T2D) have increased cancer risk. Liver cancer (LC) has a high prevalence in East Asia and is one of the leading causes of cancer…”
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Association of insomnia with incident chronic cognitive impairment in older adults with type 2 diabetes mellitus: A prospective study of the Hong Kong Diabetes Register
Published in Journal of diabetes and its complications (01-10-2023)“…To examine the risk association of insomnia with incident chronic cognitive impairment in older adults with type 2 diabetes mellitus (T2D). Between July 2010…”
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Advanced liver fibrosis predicts heart failure and hospitalizations in people with type 2 diabetes: A prospective cohort study from Hong Kong Diabetes Register
Published in Diabetes research and clinical practice (01-08-2023)“…We aimed to examine the impact of non-alcoholic fatty liver disease (NAFLD) on the clinical outcomes in patients with type 2 diabetes (T2D). Between 2013 and…”
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Young-Onset Diabetes in East Asians: From Epidemiology to Precision Medicine
Published in Endocrinology and metabolism (Seoul) (01-04-2024)“…Precision diagnosis is the keystone of clinical medicine. In East Asians, classical type 1 diabetes is uncommon in patients with youngonset diabetes diagnosed…”
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Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes-Randomized Controlled Trial (PRISM-RCT) in Chinese patients with young-onset diabetes: design, methods and baseline characteristics
Published in BMJ open diabetes research & care (19-06-2024)“…IntroductionWe designed and implemented a patient-centered, data-driven, holistic care model with evaluation of its impacts on clinical outcomes in patients…”
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One-hour post-load plasma glucose level predicts future type 2 diabetes in a community-based study of Hong Kong Chinese workforce
Published in Diabetes research and clinical practice (01-06-2024)“…We compared performance of high 1-hour PG level, impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) in predicting type 2 diabetes in a…”
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1477-P: Polygenic Risk Score (PRS) Derived from Common Variants of Monogenic Diabetes Genes (MDG) Predicts Young Onset Diabetes (YOD) and Cardiovascular(CV)-Kidney Complications
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Introduction & Objectives: Monogenic diabetes are caused by rare mutations in genes usually implicated in β-cell reserve/function. Whether their common…”
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Insights into optimal BMI from the GlasVEGAS study
Published in Nature metabolism (01-08-2024)“…A human experiment confirms the higher susceptibility of South Asians to adverse metabolic consequences with weight gain compared with white Europeans, which…”
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