Search Results - "O'brien, E."

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    The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins by Burridge, Keith, Guilluy, Christophe, Swaminathan, Vinay, Garcia-Mata, Rafael, Timothy O'Brien, E, Superfine, Richard

    Published in Nature cell biology (01-06-2011)
    “…How individual cells respond to mechanical forces is of considerable interest to biologists as force affects many aspects of cell behaviour. The application of…”
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    Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines by Swaminathan, Vinay, Mythreye, Karthikeyan, O'Brien, E Tim, Berchuck, Andrew, Blobe, Gerard C, Superfine, Richard

    Published in Cancer research (Chicago, Ill.) (01-08-2011)
    “…Cancer cells are defined by their ability to invade through the basement membrane, a critical step during metastasis. While increased secretion of proteases,…”
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    Quantum phase estimation of multiple eigenvalues for small-scale (noisy) experiments by O'Brien, Thomas E, Tarasinski, Brian, Terhal, Barbara M

    Published in New journal of physics (28-02-2019)
    “…Quantum phase estimation (QPE) is the workhorse behind any quantum algorithm and a promising method for determining ground state energies of strongly…”
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    Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics by Hobson, Chad M, Kern, Megan, O'Brien, 3rd, E Timothy, Stephens, Andrew D, Falvo, Michael R, Superfine, Richard

    Published in Molecular biology of the cell (21-07-2020)
    “…Nuclei are often under external stress, be it during migration through tight constrictions or compressive pressure by the actin cap, and the mechanical…”
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    Nearly Optimal Measurement Scheduling for Partial Tomography of Quantum States by Bonet-Monroig, Xavier, Babbush, Ryan, O’Brien, Thomas E.

    Published in Physical review. X (22-09-2020)
    “…Many applications of quantum simulation require one to prepare and then characterize quantum states by efficiently estimatingk-body reduced density matrices…”
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    Characteristics of internet addiction/pathological internet use in U.S. university students: a qualitative-method investigation by Li, Wen, O'Brien, Jennifer E, Snyder, Susan M, Howard, Matthew O

    Published in PloS one (03-02-2015)
    “…Studies have identified high rates and severe consequences of Internet Addiction/Pathological Internet Use (IA/PIU) in university students. However, most…”
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    Observing ground-state properties of the Fermi-Hubbard model using a scalable algorithm on a quantum computer by Stanisic, Stasja, Bosse, Jan Lukas, Gambetta, Filippo Maria, Santos, Raul A., Mruczkiewicz, Wojciech, O’Brien, Thomas E., Ostby, Eric, Montanaro, Ashley

    Published in Nature communications (11-10-2022)
    “…The famous, yet unsolved, Fermi-Hubbard model for strongly-correlated electronic systems is a prominent target for quantum computers. However, accurately…”
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    Nearly Optimal Quantum Algorithm for Estimating Multiple Expectation Values by Huggins, William J, Wan, Kianna, McClean, Jarrod, O'Brien, Thomas E, Wiebe, Nathan, Babbush, Ryan

    Published in Physical review letters (09-12-2022)
    “…Many quantum algorithms involve the evaluation of expectation values. Optimal strategies for estimating a single expectation value are known, requiring a…”
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    Twenty‐four‐hour ambulatory blood pressure measurement in clinical practice and research: a critical review of a technique in need of implementation by O’Brien, E.

    Published in Journal of internal medicine (01-05-2011)
    “…  O’Brien E (The Conway Institute, University College Dublin, Dublin, Ireland). Twenty‐four‐hour ambulatory blood pressure measurement in clinical practice…”
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    Simulating groundstate and dynamical quantum phase transitions on a superconducting quantum computer by Dborin, James, Wimalaweera, Vinul, Barratt, F., Ostby, Eric, O’Brien, Thomas E., Green, A. G.

    Published in Nature communications (10-10-2022)
    “…The phenomena of quantum criticality underlie many novel collective phenomena found in condensed matter systems. They present a challenge for classical and…”
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    Vertical Light Sheet Enhanced Side-View Imaging for AFM Cell Mechanics Studies by Beicker, Kellie, O’Brien, E. Timothy, Falvo, Michael R., Superfine, Richard

    Published in Scientific reports (24-01-2018)
    “…The ability to measure dynamic structural changes within a cell under applied load is essential for developing more accurate models of cell mechanics and…”
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    Quantum error mitigation by Cai, Zhenyu, Babbush, Ryan, Benjamin, Simon C., Endo, Suguru, Huggins, William J., Li, Ying, McClean, Jarrod R., O’Brien, Thomas E.

    Published in Reviews of modern physics (01-10-2023)
    “…For quantum computers to successfully solve real-world problems, it is necessary to tackle the challenge of noise: the errors that occur in elementary physical…”
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    Localized Tensional Forces on PECAM-1 Elicit a Global Mechanotransduction Response via the Integrin-RhoA Pathway by Collins, Caitlin, Guilluy, Christophe, Welch, Christopher, O’Brien, E. Timothy, Hahn, Klaus, Superfine, Richard, Burridge, Keith, Tzima, Ellie

    Published in Current biology (20-11-2012)
    “…Mechanical forces regulate cell behavior and function during development, differentiation, and tissue morphogenesis. In the vascular system, forces produced by…”
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    Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction by Lee, Hyunna T, Sharek, Lisa, O'Brien, E Timothy, Urbina, Fabio L, Gupton, Stephanie L, Superfine, Richard, Burridge, Keith, Campbell, Sharon L

    Published in PloS one (04-09-2019)
    “…Vinculin (Vcn) is a ubiquitously expressed cytoskeletal protein that links transmembrane receptors to actin filaments, and plays a key role in regulating cell…”
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    Photolytic Aging of Secondary Organic Aerosol: Evidence for a Substantial Photo-Recalcitrant Fraction by O’Brien, Rachel E, Kroll, Jesse H

    Published in The journal of physical chemistry letters (18-07-2019)
    “…Photolytic aging has been proposed as a major mass loss mechanism for atmospheric secondary organic aerosol (SOA). However, estimated mass loss rates vary by…”
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    Combined Selective Plane Illumination Microscopy and FRAP Maps Intranuclear Diffusion of NLS-GFP by Hobson, Chad M., O’Brien, E. Timothy, Falvo, Michael R., Superfine, Richard

    Published in Biophysical journal (04-08-2020)
    “…Since its initial development in 1976, fluorescence recovery after photobleaching (FRAP) has been one of the most popular tools for studying diffusion and…”
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    Site-specific glycosylation regulates the form and function of the intermediate filament cytoskeleton by Tarbet, Heather J, Dolat, Lee, Smith, Timothy J, Condon, Brett M, O'Brien, 3rd, E Timothy, Valdivia, Raphael H, Boyce, Michael

    Published in eLife (07-03-2018)
    “…Intermediate filaments (IF) are a major component of the metazoan cytoskeleton and are essential for normal cell morphology, motility, and signal transduction…”
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