Search Results - "O'brien, E."
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The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins
Published in Nature cell biology (01-06-2011)“…How individual cells respond to mechanical forces is of considerable interest to biologists as force affects many aspects of cell behaviour. The application of…”
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Long-Term Outcomes After Bariatric Surgery: a Systematic Review and Meta-analysis of Weight Loss at 10 or More Years for All Bariatric Procedures and a Single-Centre Review of 20-Year Outcomes After Adjustable Gastric Banding
Published in Obesity surgery (01-01-2019)“…Introduction Durability is a key requirement for the broad acceptance of bariatric surgery. We report on durability at and beyond 10 years with a systematic…”
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3
Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines
Published in Cancer research (Chicago, Ill.) (01-08-2011)“…Cancer cells are defined by their ability to invade through the basement membrane, a critical step during metastasis. While increased secretion of proteases,…”
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4
Quantum phase estimation of multiple eigenvalues for small-scale (noisy) experiments
Published in New journal of physics (28-02-2019)“…Quantum phase estimation (QPE) is the workhorse behind any quantum algorithm and a promising method for determining ground state energies of strongly…”
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Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics
Published in Molecular biology of the cell (21-07-2020)“…Nuclei are often under external stress, be it during migration through tight constrictions or compressive pressure by the actin cap, and the mechanical…”
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Nearly Optimal Measurement Scheduling for Partial Tomography of Quantum States
Published in Physical review. X (22-09-2020)“…Many applications of quantum simulation require one to prepare and then characterize quantum states by efficiently estimatingk-body reduced density matrices…”
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Characteristics of internet addiction/pathological internet use in U.S. university students: a qualitative-method investigation
Published in PloS one (03-02-2015)“…Studies have identified high rates and severe consequences of Internet Addiction/Pathological Internet Use (IA/PIU) in university students. However, most…”
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Observing ground-state properties of the Fermi-Hubbard model using a scalable algorithm on a quantum computer
Published in Nature communications (11-10-2022)“…The famous, yet unsolved, Fermi-Hubbard model for strongly-correlated electronic systems is a prominent target for quantum computers. However, accurately…”
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Nearly Optimal Quantum Algorithm for Estimating Multiple Expectation Values
Published in Physical review letters (09-12-2022)“…Many quantum algorithms involve the evaluation of expectation values. Optimal strategies for estimating a single expectation value are known, requiring a…”
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Twenty‐four‐hour ambulatory blood pressure measurement in clinical practice and research: a critical review of a technique in need of implementation
Published in Journal of internal medicine (01-05-2011)“… O’Brien E (The Conway Institute, University College Dublin, Dublin, Ireland). Twenty‐four‐hour ambulatory blood pressure measurement in clinical practice…”
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Simulating groundstate and dynamical quantum phase transitions on a superconducting quantum computer
Published in Nature communications (10-10-2022)“…The phenomena of quantum criticality underlie many novel collective phenomena found in condensed matter systems. They present a challenge for classical and…”
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Vertical Light Sheet Enhanced Side-View Imaging for AFM Cell Mechanics Studies
Published in Scientific reports (24-01-2018)“…The ability to measure dynamic structural changes within a cell under applied load is essential for developing more accurate models of cell mechanics and…”
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13
Quantum error mitigation
Published in Reviews of modern physics (01-10-2023)“…For quantum computers to successfully solve real-world problems, it is necessary to tackle the challenge of noise: the errors that occur in elementary physical…”
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Localized Tensional Forces on PECAM-1 Elicit a Global Mechanotransduction Response via the Integrin-RhoA Pathway
Published in Current biology (20-11-2012)“…Mechanical forces regulate cell behavior and function during development, differentiation, and tissue morphogenesis. In the vascular system, forces produced by…”
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Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction
Published in PloS one (04-09-2019)“…Vinculin (Vcn) is a ubiquitously expressed cytoskeletal protein that links transmembrane receptors to actin filaments, and plays a key role in regulating cell…”
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16
Photolytic Aging of Secondary Organic Aerosol: Evidence for a Substantial Photo-Recalcitrant Fraction
Published in The journal of physical chemistry letters (18-07-2019)“…Photolytic aging has been proposed as a major mass loss mechanism for atmospheric secondary organic aerosol (SOA). However, estimated mass loss rates vary by…”
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17
Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders
Published in Genome Biology (12-11-2018)“…Genetic influences on gene expression in the human fetal brain plausibly impact upon a variety of postnatal brain-related traits, including susceptibility to…”
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Combined Selective Plane Illumination Microscopy and FRAP Maps Intranuclear Diffusion of NLS-GFP
Published in Biophysical journal (04-08-2020)“…Since its initial development in 1976, fluorescence recovery after photobleaching (FRAP) has been one of the most popular tools for studying diffusion and…”
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Coordinated, Collaborative Management of an Outbreak: Lessons for Maintenance of Patient Trust
Published in The Annals of thoracic surgery (01-08-2022)Get full text
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Site-specific glycosylation regulates the form and function of the intermediate filament cytoskeleton
Published in eLife (07-03-2018)“…Intermediate filaments (IF) are a major component of the metazoan cytoskeleton and are essential for normal cell morphology, motility, and signal transduction…”
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