Search Results - "O'Young, Jason"

Control of Calcium Oxalate Crystal Growth by Face-Specific Adsorption of an Osteopontin Phosphopeptide by Grohe, Bernd, O'Young, Jason, Ionescu, D. Andrei, Lajoie, Gilles, Rogers, Kem A, Karttunen, Mikko, Goldberg, Harvey A, Hunter, Graeme K

“…Mineral-associated proteins have been proposed to regulate many aspects of biomineralization, including the location, type, orientation, shape, and texture of…”
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Roles of electrostatics and conformation in protein-crystal interactions by Azzopardi, Paul V, O'Young, Jason, Lajoie, Gilles, Karttunen, Mikko, Goldberg, Harvey A, Hunter, Graeme K

“…In vitro studies have shown that the phosphoprotein osteopontin (OPN) inhibits the nucleation and growth of hydroxyapatite (HA) and other biominerals. In vivo,…”
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Matrix Gla Protein Inhibits Ectopic Calcification by a Direct Interaction with Hydroxyapatite Crystals by O’Young, Jason, Liao, Yinyin, Xiao, Yizhi, Jalkanen, Jari, Lajoie, Gilles, Karttunen, Mikko, Goldberg, Harvey A, Hunter, Graeme K

“…Mice lacking the gene encoding matrix gla protein (MGP) exhibit massive mineral deposition in blood vessels and die soon after birth. We hypothesize that MGP…”
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The Flexible Polyelectrolyte Hypothesis of Protein−Biomineral Interaction by Hunter, Graeme K, O’Young, Jason, Grohe, Bernd, Karttunen, Mikko, Goldberg, Harvey A

“…Biomineralization is characterized by a high degree of control over the location, nature, size, shape, and orientation of the crystals formed. For many years,…”
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Escherichia coli glyoxalase II is a binuclear zinc-dependent metalloenzyme by O’Young, Jason, Sukdeo, Nicole, Honek, John F.

“…Cytotoxic methylglyoxal is detoxified by the two-enzyme glyoxalase system. Glyoxalase I (GlxI) catalyzes conversion of non-enzymatically produced…”
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Citrate modulates calcium oxalate crystal growth by face-specific interactions by Grohe, Bernd, O'Young, Jason, Langdon, Aaron, Karttunen, Mikko, Goldberg, Harvey A, Hunter, Graeme K

“…Because of its ability to inhibit the growth of calcium oxalate monohydrate (COM) crystals, citrate plays an important role in preventing the formation of…”
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Role of phosphate groups in inhibition of calcium oxalate crystal growth by osteopontin by Hunter, Graeme K, Grohe, Bernd, Jeffrey, Sara, O'Young, Jason, Sørensen, Esben S, Goldberg, Harvey A

“…Osteopontin (OPN) inhibits the growth of calcium oxalate monohydrate (COM) and other crystal phases in a phosphorylation-dependent manner. In the present…”
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Phosphorylation of osteopontin peptides mediates adsorption to and incorporation into calcium oxalate crystals by O'Young, Jason, Chirico, Sara, Al Tarhuni, Nehal, Grohe, Bernd, Karttunen, Mikko, Goldberg, Harvey A, Hunter, Graeme K

“…Phosphorylated peptides of osteopontin (OPN) have been shown to inhibit the growth of the {100} face of calcium oxalate monohydrate (COM). The inhibitory…”
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Phosphorylation of Ser136 is critical for potent bone sialoprotein-mediated nucleation of hydroxyapatite crystals by Baht, Gurpreet S, O'Young, Jason, Borovina, Antonia, Chen, Hong, Tye, Coralee E, Karttunen, Mikko, Lajoie, Gilles A, Hunter, Graeme K, Goldberg, Harvey A

“…Acidic phosphoproteins of mineralized tissues such as bone and dentin are believed to play important roles in HA (hydroxyapatite) nucleation and growth. BSP…”
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Control of Calcium Oxalate Crystal Growth by Face-Specific Adsorption of an Osteopontin Phosphopeptide by Grohe, Bernd, O'Young, Jason, Ionescu, DAndrei, Lajoie, Gilles, Rogers, Kem A, Karttunen, Mikko, Goldberg, Harvey A, Hunter, Graeme K

“…Mineral-associated proteins have been proposed to regulate many aspects of biomineralization, including the location, type, orientation, shape, and texture of…”
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Molecular dynamics simulations of peptide adsorption to a mineral surface by O’Young, Jason, Grohe, Bernd, Karttunen, Mikko, Goldberg, Harvey, Hunter, Graeme

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