Search Results - "O'Toole, Lorcan"

CompARE: study protocol for a phase III randomised controlled platform trial comparing alternative regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer by Mehanna, Hisham, Gaunt, Piers, Kong, Anthony, Hartley, Andrew, Sanghera, Paul, Forster, Martin, Sen, Mehmet, Paleri, Vinidh, Fong, Charles, Geropantas, Dinos, Srinivasan, Devraj, Garikipati, Satya, Moleron, Rafael, Casswell, Georgina, Aynsley, Eleanor, Ward, Amy, O'Toole, Lorcan, Mirza, Arafat, Firth, Charlotte, Humphreys, Isla, Fulton-Lieuw, Tessa, Roques, Tom, Nankivell, Paul

“…Patients with intermediate and high-risk oropharyngeal cancer (OPC) have poorer response to standard treatment and poorer overall survival compared to low-risk…”
Get full text

A multi-centre survey reveals variations in the standard treatments and treatment modifications for head and neck cancer patients during Covid-19 pandemic by Vasiliadou, Ifigenia, Noble, David, Hartley, Andrew, Moleron, Rafael, Sanghera, Paul, Urbano, Teresa Guerrero, Schipani, Stefano, Gujral, Dorothy, Foran, Bernie, Bhide, Shree, Haridass, Anoop, Nathan, Kannon, Michaelidou, Andriana, Sen, Mehmet, Geropantas, Konstantinos, Joseph, Mano, O'Toole, Lorcan, Griffin, Matthew, Pettit, Laura, Chambers, Jonathan, Jankowska, Petra, De Winton, Emma, Goranova, Rebecca, Singh, Niveditha, Shah, Ketan, Kong Conceptualisation, Anthony

“…•We investigated the effect of COVID-19 pandemic in the treatment practice of head and neck oncology patients in the UK.•There is variability in practice in…”
Get full text

Response to ‘British Association of Dermatologists guidelines for the management of adults with basal cell carcinoma 2021’: vismodegib and indications for its use by Shariatmadari, Isla, Matteucci, Paolo, Barreda, Alan, O’Toole, Lorcan

Get full text

Electrochemotherapy vs radiotherapy in the treatment of primary cutaneous malignancies or cutaneous metastases from primary solid organ malignancies: A systematic review and narrative synthesis by McMillan, Angus Torry, McElroy, Luke, O'Toole, Lorcan, Matteucci, Paolo, Totty, Joshua Philip

“…Electrochemotherapy has gained international traction and commendation in national guidelines as an effective tool in the management of cutaneous malignancies…”
Get full text

Precision micro-milling process: state of the art by O’Toole, Lorcan, Kang, Cheng-Wei, Fang, Feng-Zhou

“…Micro-milling is a precision manufacturing process with broad applications across the biomedical, electronics, aerospace, and aeronautical industries owing to…”
Get full text

Optimal tool design in micro-milling of difficult-to-machine materials by O’Toole, Lorcan, Fang, Feng-Zhou

“…The limitations of significant tool wear and tool breakage of commercially available fluted micro-end mill tools often lead to ineffective and inefficient…”
Get full text

Manufacturing of Soft Contact Lenses Using Reusable and Reliable Cyclic Olefin Copolymer Moulds by Musgrave, Christopher, O'Toole, Lorcan, Mao, Tianyu, Li, Qing, Lai, Min, Fang, Fengzhou

“…We present experimental evidence of reusable, reliable cyclic olefin copolymer (COC) moulds in soft contact lens manufacturing. The moulds showed high…”
Get full text

Determination of Johnson-Cook plasticity model parameters for CoCrMo alloy by O’Toole, Lorcan, Haridas, Ravi Sankar, Mishra, Rajiv S., Fang, Fengzhou

“…Numerical modelling of Cobalt-Chromium-Molybdenum (CoCrMo) alloys allows for rapid and economical evaluation of machining processes, such as grinding, turning,…”
Get full text

Electrochemotherapy vs radiotherapy in the treatment of primary cutaneous malignancies or cutaneous metastases from primary solid organ malignancies: a protocol for a systematic review and meta-analysis by McMillan, Angus, McElroy, Luke, O'Toole, Lorcan, Matteucci, Paolo, Totty, Joshua P

“…Abstract Electrochemotherapy has emerged as a valuable tool in the treatment of cutaneous malignancies that are unamenable to surgical resection. Despite…”
Get full text

Electrochemotherapy vs radiotherapy in the treatment of primary cutaneous malignancies or cutaneous metastases from primary solid organ malignancies: A systematic review and narrative synthesis by Mcmillan, Angus, McElroy, Luke, O'Toole, Lorcan, Matteucci, Paolo, Totty, Joshua

Get full text

Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial by Mehanna, Hisham, Robinson, Max, Hartley, Andrew, Kong, Anthony, Foran, Bernadette, Fulton-Lieuw, Tessa, Dalby, Matthew, Mistry, Pankaj, Sen, Mehmet, O'Toole, Lorcan, Al Booz, Hoda, Dyker, Karen, Moleron, Rafael, Whitaker, Stephen, Brennan, Sinead, Cook, Audrey, Griffin, Matthew, Aynsley, Eleanor, Rolles, Martin, De Winton, Emma, Chan, Andrew, Srinivasan, Devraj, Nixon, Ioanna, Grumett, Joanne, Leemans, C René, Buter, Jan, Henderson, Julia, Harrington, Kevin, McConkey, Christopher, Gray, Alastair, Dunn, Janet, Moleron, Rafael, McArdle, Orla, Dyker, Karen, Al Booz, Hoda, O'Toole, Lorcan, Cook, Audrey, Husband, David, Loo, Vivienne, Soe, Win, Aynsley, Eleanor, Sridhar, Thiagarajan, Jankowska, Petra, Joseph, Mano, Geropantas, Konstantinos, Vaidya, Deepali, Griffin, Matthew, Hartley, Andrew, Vijayan, Rengarajan, Hwang, David, Harrington, Kevin, Pettit, Laura, Whitaker, Stephen, De Winton, Emma, Rolles, Martin, Brennan, Sinéad, Sen, Mehmet, Mendes, Ruheena, Forster, Martin, Chan, Andrew, Evans, Mererid, Buter, Jan, Srinivasan, Devraj, Foran, Bernie, Nankivell, Paul, Bryant, Jennifer, Sharma, Neil, Spruce, Rachel, Brooks, Jill, Batis, Nikos, Roques, Tom, Bidmead, Margaret, Yang, Huiqi, Nutting, Christopher, Tyler, Justine, Henderson, Julia, Baines, Helen, Gasnier, Anne, Miles, Elizabeth, Clark, Catharine

“…The incidence of human papillomavirus (HPV)-positive oropharyngeal cancer, a disease affecting younger patients, is rapidly increasing. Cetuximab, an epidermal…”
Get full text

Factors influencing Hen Harrier Circus cyaneus territory site selection and breeding success by Caravaggi, Anthony, Irwin, Sandra, Lusby, John, Ruddock, Marc, O'Toole, Lorcán, Mee, Allan, Nagle, Tony, O'Neill, Shane, Tierney, David, McCarthy, Alan, O'Halloran, John

“…Capsule: Our findings regarding Hen Harrier Circus cyaneus territory site selection and breeding success in Ireland offer an opportunity for the development of…”
Get full text

Anthropogenic pressures within the breeding range of the Hen Harrier Circus cyaneus in Ireland by Caravaggi, Anthony, Irwin, Sandra, Lusby, John, Ruddock, Marc, Mee, Allan, Nagle, Tony, O'Toole, Lorcán, O'Neill, Shane, O'Halloran, John

“…Patterns in the frequency and co-occurrence of anthropogenic pressures associated with suitable breeding habitat for Hen Harriers Circus cyaneus demonstrates…”
Get full text

Developing a complex intervention for the outpatient management of incidentally diagnosed pulmonary embolism in cancer patients by Palmer, June, Bozas, George, Stephens, Andrew, Johnson, Miriam, Avery, Ged, O'Toole, Lorcan, Maraveyas, Anthony

“…Most patients with pulmonary embolism (PE) spend 5-7 days in hospital even though only 4.5% will develop serious complications during this time. In particular,…”
Get full text

history of eagles in Britain and Ireland: an ecological review of placename and documentary evidence from the last 1500 years by Evans, Richard J, O'Toole, Lorcán, Whitfield, D. Philip

“…Capsule The loss of eagles from large tracts of lowland and upland habitat in Britain and Ireland over the last 1500 years is attributed to human activity.Aim…”
Get full text

Analysis of hydration and antiemetics policies in preventing cisplatin-related gastrointestinal and renal toxicities in low-risk human papillomavirus positive-oropharyngeal cancer (HPV+OPC) patients undergoing chemoradiation in De-ESCALaTE trial by Kong, Anthony Hee, Mistry, Pankaj, Evans, Mererid, Hartley, Andrew G. J., Fulton-Lieuw, Tessa, Jones, David, Dalby, Matthew, Gray, Alastair, Foran, Bernadette, Sen, Mehmet, O'Toole, Lorcan, Al-Booz, H, Dyker, Karen, Moleron Mancebo, Rafael, Whittaker, Stephen, Brennan, Sinead Maire, Cook, Audrey, Griffin, Matthew, Dunn, Janet, Mehanna, Hisham Mohamed

“…Abstract only 6076 Background: The De-ESCALaTE trial confirmed the superiority of cisplatin over cetuximab in combination with radiotherapy for the treatment…”
Get full text

Transoral endoscopic base of tongue mucosectomy for investigation of unknown primary cancers of head and neck by Wallis, S., O'Toole, L., Karsai, L., Jose, J.

“…Cancer of the unknown primary (CUP) makes up 2-4% of new head and neck squamous cell carcinoma (SCC) diagnoses. This scenario is recognised as a diagnostic…”
Get full text

Trifluridine/tipiracil (Lonsurf®) use in metastatic colorectal cancer: efficacy outcome and toxicity in a single UK centre by Boon, Ian S., Joyce, Helen, Kabir, Adnan, Goodman, Max, Brown, Victoria, Roy, Rajarshi, O'Toole, Lorcan, Dhadda, Amandeep S.

Get full text

Experimental study on efficient micro-milling of Alumina with PCD and cBN micro-milling tools by O'Toole, Lorcan, Fang, Fengzhou

“…Currently, micro-milling of very hard and brittle materials such as ceramics is relatively unfeasible due to significant tool wear, tool breakage and poor…”
Get full text

Re-introduction of the golden eagle into the Republic of Ireland by O’Toole, Lorcan, Fielding, Alan H., Haworth, Paul F.

“…The golden eagle ( Aquila chrysaetos) became extinct in the Republic of Ireland in about 1912. Historical evidence suggests that, in the early nineteenth…”
Get full text