Search Results - "O'Toole, KM"

A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status by Rheinwald, James G, Hahn, William C, Ramsey, Matthew R, Wu, Jenny Y, Guo, Zongyou, Tsao, Hensin, De Luca, Michele, Catricalà, Caterina, O'Toole, Kathleen M

“…With increasing frequency during serial passage in culture, primary human keratinocytes express p16(INK4A) (p16) and undergo senescence arrest. Keratinocytes…”
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Cribriform carcinoma of the prostate and cribriform prostatic intraepithelial neoplasia : Incidence and clinical implications by RUBIN, M. A, DE LA TAILLE, A, BAGIELLA, E, OLSSON, C. A, O'TOOLE, K. M

“…Cribriform neoplasia of the prostate can be recognized easily. However, controversy persists regarding terminology, particularly with the intraductal spread of…”
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Anti-vegf antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor by Rowe, Dorothy H., Huang, Jianzhong, Kayton, Mark L, Thompson, Richard, Troxel, Andrea, O'Toole, Kathleen M., Yamashiro, Darrell, Stolar, Charles J.H., Kandel, Jessica J.

“…Vascular endothelial growth factor (VEGF) has been shown previously to correlate with tumor growth and metastasis in an experimental model of anaplastic Wilms'…”
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Perineural invasion on prostate needle biopsy: an independent predictor of final pathologic stage by de la Taille, Alexandre, Katz, Aaron, Bagiella, Emilia, Olsson, Carl A, O’Toole, Kathleen M, Rubin, Mark A

“…Objectives. To examine the significance of perineural invasion (PNI) in predicting pathologic findings in patients treated by radical prostatectomy, because a…”
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Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia by Schumer, M, Colombel, MC, Sawczuk, IS, Gobe, G, Connor, J, O'Toole, KM, Olsson, CA, Wise, GJ, Buttyan, R

“…A multiparametric analysis to demonstrate that even brief periods of arterial clamping can initiate extensive cell loss in a rat kidney through the process of…”
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Should a Gleason score be assigned to a minute focus of carcinoma on prostate biopsy? by RUBIN, Mark A, DUNN, Rodney, KAMBHAM, Neeraja, MISICK, Carolyn Pearsall, O'TOOLE, Kathleen M

“…The grading system for prostate carcinoma devised by Gleason is a strong prognostic indicator. The primary and secondary patterns are combined to give a tumor…”
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Can perineural invasion on prostate needle biopsy predict prostate specific antigen recurrence after radical prostatectomy? by de la Taille, A, Rubin, M A, Bagiella, E, Olsson, C A, Buttyan, R, Burchardt, T, Knight, C, O'Toole, K M, Katz, A E

“…We evaluated the role of perineural invasion identified on prostate needle biopsy as a predictor of prostate specific antigen (PSA) recurrence after radical…”
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Heterotopic Gastric Mucosa in the Gallbladder: A Rare Cause of Massive Hemobilia by Yoon, Angela J, Cowles, Robert A, Stylianos, Steven, O'Toole, Kathleen M

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Suppression of primary tumor growth in a mouse model of human neuroblastoma by Rowe, Dorothy H., Huang, Jianzhong, Li, Jin, Manley, Christina, O'Toole, Kathleen M., Stolar, Charles J., Yamashiro, Darrell J., Kandel, Jessica J.

“…Background/Purpose: Neuroblastoma is the most common tumor of the abdomen in children. Consistently effective treatments are lacking for aggressive disease…”
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The effect of cystectomy, and perioperative methotrexate, vinblastine, doxorubicin and cisplatin chemotherapy on the risk and pattern of relapse in patients with muscle invasive bladder cancer by Ennis, R D, Petrylak, D P, Singh, P, Bagiella, E, O'Toole, K M, Benson, M C, Olsson, C A

“…Trials have demonstrated decreased relapse with perioperative methotrexate, vinblastine, doxorubicin and cisplatin (M-VAC) chemotherapy in patients with muscle…”
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Changes in biochemical disease-free survival rates as a result of adoption of the consensus conference definition in patients with clinically localized prostate cancer treated with external-beam radiotherapy by Ennis, R D, Malyszko, B K, Heitjan, D F, Rubin, M A, O'Toole, K M, Schiff, P B

“…The optimal definition of biochemical recurrence of prostate cancer after definitive radiotherapy remains elusive. Different institutions have developed their…”
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Metastasis correlates with production of vascular endothelial growth factor in a murine model of human Wilms' tumor by Kayton, Mark L., Rowe, Dorothy H., O'Toole, Kathleen M., Thompson, Richard B., Schwarz, Margaret A., Stolar, Charles J.H., Kandel, Jessica J.

“…Background/Purpose: The growth and spread of solid tumors are critically dependent on the induction of angiogenesis. We hypothesized that vascular endothelial…”
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Postprostatectomy salvage radiation therapy for prostate cancer: Impact of pathological and biochemical variables and prostate fossa biopsy by MOSBACHER, Marc R, SCHIFF, Peter B, O'TOOLE, Kathleen M, BENSON, Mitchell C, OLSSON, Carl A, BRODY, Rachel A, ENNIS, Ronald D

“…A subgroup of prostate cancer patients who have experienced biochemical relapse after radical retropubic prostatectomy (RRP) can benefit from radiation therapy…”
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Pathological angiogenesis in a murine model of human Wilms' tumor by Rowe, Dorothy H., Kayton, Mark L., O'Toole, Kathleen M., Ingram, Mark, Stolar, Charles J.H., Kandel, Jessica J.

“…Background/Purpose: Pathological vascular architecture is a feature of neoangiogenic processes such as diseases of the retina and tumor growth. The authors…”
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Biologic classification as an alternative to anatomic staging for clinically localized prostate cancer: a proposal based on patients treated with external beam radiotherapy by Ennis, Ronald D., Malyszko, Bozena K., Rescigno, John, Whitman, Adam E., Heitjan, Daniel F., O'Toole, Kathleen M., Rubin, Mark, Schiff, Peter B.

“…Objectives. The prognostic significance of clinical stage in patients with prostate cancer who are treated with external beam radiotherapy is unclear. This…”
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A metastasizing model of anaplastic human Wilms tumor in the nude mouse by Marvin, M R, Kayton, M L, O'Toole, K M, Rowe, D H, DeRosa, C, Kindred, A, Trokhan, S, Chabot, J, Kandel, J J

“…Reproducible animal models of Wilms tumor have been difficult to establish. We describe a model in which cells, banked from a patient with metastatic Wilms…”
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Molecular staging of prostate cancer with the use of an enhanced reverse transcriptase-PCR assay by Katz, A E, Olsson, C A, Raffo, A J, Cama, C, Perlman, H, Seaman, E, O'Toole, K M, McMahon, D, Benson, M C, Buttyan, R

“…Because up to 40 percent of surgically treated patients with prostate cancer are subsequently found to be clinically understaged, a more sensitive staging…”
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Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone- refractory human prostate cancers by Colombel, M, Symmans, F, Gil, S, O'Toole, KM, Chopin, D, Benson, M, Olsson, CA, Korsmeyer, S, Buttyan, R

“…The oncoprotein encoded by bc1-2 is unique because of its intracellular location (a mitochondrial membrane protein) and apparent mode of action (suppression of…”
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Colonoscopic screening for neoplasms in asymptomatic first-degree relatives of colon cancer patients. A controlled, prospective study by Guillem, J G, Forde, K A, Treat, M R, Neugut, A I, O'Toole, K M, Diamond, B E

“…Individuals with a family history of colorectal cancer are believed to be at an increased risk of developing colorectal neoplasia. To estimate this risk and…”
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Detection of circulating prostate carcinoma cells via an enhanced reverse transcriptase-polymerase chain reaction assay in patients with early stage prostate carcinoma independence from other pretreatment characteristics by ENNIS, R. D, KATZ, A. E, DE VRIES, G. M, HEITJAN, D. F, O'TOOLE, K. M, RUBIN, M, BUTTYAN, R, BENSON, M. C, SCHIFF, P. B

“…Circulating prostate cells can be detected in the venous blood of patients with clinically localized prostate carcinoma by applying reverse…”
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