Search Results - "O'TUATHAIGH, Colm M. P"
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Medical students' empathy and attitudes towards professionalism: Relationship with personality, specialty preference and medical programme
Published in PloS one (02-05-2019)“…Existing research has suggested that self-reported empathy in medical students is moderated by personality traits and diverse demographic and educational…”
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Age-related hearing loss and provider-patient communication across primary and secondary care settings: a cross-sectional study
Published in Age and ageing (24-08-2020)“…Abstract Background The prevalence of age-related hearing loss (ARHL) increases with age. Older adults are amongst the most dependent users of healthcare and…”
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Developmental Genes and Regulatory Proteins, Domains of Cognitive Impairment in Schizophrenia Spectrum Psychosis and Implications for Antipsychotic Drug Discovery: The Example of Dysbindin-1 Isoforms and Beyond
Published in Frontiers in pharmacology (29-01-2020)“…Alongside positive and negative symptomatology, deficits in working memory, attention, selective learning processes, and executive function have been widely…”
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Genetic dissection of the psychotomimetic effects of cannabinoid exposure
Published in Progress in neuro-psychopharmacology & biological psychiatry (03-07-2014)“…Cannabis use is an established risk factor for the development of schizophrenia and related psychotic disorders. Factors that may mediate susceptibility to the…”
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Medical student perceptions of radiology use in anatomy teaching
Published in Anatomical sciences education (01-11-2015)“…The use of radiology in the teaching of anatomy to medical students is gaining in popularity; however, there is wide variation in how and when radiology is…”
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Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous ‘knockout’ of the schizophrenia risk gene neuregulin-1
Published in Progress in neuro-psychopharmacology & biological psychiatry (15-02-2008)“…Clinical genetic studies have implicated neuregulin-1 [NRG1] as a leading susceptibility gene for schizophrenia. NRG1 is known to play a significant role in…”
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Dysregulation of Specialized Delay/Interference-Dependent Working Memory Following Loss of Dysbindin-1A in Schizophrenia-Related Phenotypes
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2017)“…Dysbindin-1, a protein that regulates aspects of early and late brain development, has been implicated in the pathobiology of schizophrenia. As the functional…”
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Chronic Adolescent Exposure to Delta-9-Tetrahydrocannabinol in COMT Mutant Mice: Impact on Indices of Dopaminergic, Endocannabinoid and GABAergic Pathways
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2012)“…Cannabis use confers a two-fold increase in risk for psychosis, with adolescent use conferring an even greater risk. A high-low activity polymorphism in…”
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Cannabis Use, Schizotypy and Kamin Blocking Performance
Published in Frontiers in psychiatry (23-11-2021)“…Cannabis use has been associated with increased risk for a first episode of psychosis and inappropriate assignment of salience to extraneous stimuli has been…”
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Impact of hearing loss on clinical interactions between older adults and health professionals: a systematic review
Published in European geriatric medicine (01-12-2020)“…Key summary points Objectives This review quantified the extent to which hearing loss is cited and/or accounted for in studies of older adult interactions with…”
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Association between learning style preferences and anatomy assessment outcomes in graduate-entry and undergraduate medical students
Published in Anatomical sciences education (08-07-2016)“…An improved understanding of the relationship between anatomy learning performance and approaches to learning can lead to the development of a more tailored…”
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Susceptibility genes for schizophrenia: Characterisation of mutant mouse models at the level of phenotypic behaviour
Published in Neuroscience and biobehavioral reviews (2007)“…A wealth of evidence indicates that schizophrenia is heritable. However, the genetic mechanisms involved are poorly understood. Furthermore, it may be that…”
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Genetically modified mice related to schizophrenia and other psychoses: Seeking phenotypic insights into the pathobiology and treatment of negative symptoms
Published in European neuropsychopharmacology (01-05-2014)“…Abstract Modelling negative symptoms in any animal model, particularly in mice mutant for genes related to schizophrenia, is complicated by the absence of the…”
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Mutant mouse models: genotype-phenotype relationships to negative symptoms in schizophrenia
Published in Schizophrenia bulletin (01-03-2010)“…Negative symptoms encompass diminution in emotional expression and motivation, some of which relate to human attributes that may not be accessible readily in…”
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Neuregulin-1 signaling in schizophrenia: 'Jack of all trades' or master of some?
Published in Expert review of neurotherapeutics (01-01-2009)Get more information
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Advancing a functional genomics for schizophrenia: Psychopathological and cognitive phenotypes in mutants with gene disruption
Published in Brain research bulletin (30-09-2010)“…Abstract Schizophrenia is a complex, heritable psychotic disorder in which numerous genes and environmental adversities appear to interact in determining…”
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Bridging the divide between medical school and clinical practice: identification of six key learning outcomes for an undergraduate preparatory course in radiology
Published in Insights into imaging (12-02-2021)“…Background There exists a significant divide between what is learnt in medical school and subsequently what is required to practice medicine effectively…”
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Relevance of anatomy to medical education and clinical practice: perspectives of medical students, clinicians, and educators
Published in Perspectives on medical education (01-12-2016)“…Introduction Against a backdrop of ever-changing diagnostic and treatment modalities, stakeholder perceptions (medical students, clinicians, anatomy educators)…”
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Genetic models of schizophrenia and related psychotic disorders: progress and pitfalls across the methodological “minefield”
Published in Cell and tissue research (01-10-2013)“…The challenge of modelling a complex and multifaceted disorder such as schizophrenia is epitomised by the considerable degree of phenotypic variability…”
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Mutant mouse models: phenotypic relationships to domains of psychopathology and pathobiology in schizophrenia
Published in Schizophrenia bulletin (01-03-2010)“…The present series of review articles seeks to elaborate how current findings in mutant mice may inform on the relationship between candidate genes and…”
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