Search Results - "O'Sullivan, Lydia"

Non-inferiority randomised phase 3 trial comparing two radiation schedules (single vs. five fractions) in malignant spinal cord compression by Thirion, Pierre G., Dunne, Mary T., Kelly, Paul J., Flavin, Aileen, O’Sullivan, Joe M., Hacking, Dayle, Sasiadek, Wojciech, Small, Cormac, Pomeroy, Maeve M., Martin, Joseph, McArdle, Orla, Parker, Imelda, O’Sullivan, Lydia S., Shannon, Aoife M., Clayton-Lea, Angela, Collins, Conor D., Stevenson, Michael R., Alvarez-Iglesias, Alberto, Armstrong, John G., Moriarty, Michael

“…Background The optimal EBRT schedule for MSCC is undetermined. Our aim was to determine whether a single fraction (SF) was non-inferior to five daily fractions…”
Get full text

Readability and understandability of clinical research patient information leaflets and consent forms in Ireland and the UK: a retrospective quantitative analysis by O'Sullivan, Lydia, Sukumar, Prasanth, Crowley, Rachel, McAuliffe, Eilish, Doran, Peter

“…ObjectivesThe first aim of this study was to quantify the difficulty level of clinical research Patient Information Leaflets/Informed Consent Forms (PILs/ICFs)…”
Get full text

Trial participants' self-reported understanding of randomisation phrases in participation information leaflets can be high, but acceptability of some descriptions is low, especially those linked to gambling and luck by Shiely, Frances, Murphy, Ellen, Gilles, Katie, Hood, Kerry, O'Sullivan, Lydia, Harman, Nicola, Isaacs, Talia, Treweek, Shaun

“…Evidence indicates that trial participants often struggle to understand participant information leaflets (PILs) for clinical trials, including the concept of…”
Get full text

Influence of Beef Hot Carcass Weight on Sensory Characteristics of Strip Loin, Eye of Round, and Denver Cut Steaks by Bakker, Christina E, Egolf, Samantha R, O'Sullivan, Lydia M, Cox, Ryan B, Rode-Atkins, Heather R, Blair, Amanda D, Underwood, Keith R, Grubbs, J Kyle

“…The objective of this research was to investigate the influence of beef hot carcass weight (HCW) on consumer sensory attributes. Beef carcasses (n = 116) were…”
Get full text

Ethical values and principles to guide the fair allocation of resources in response to a pandemic: a rapid systematic review by O'Sullivan, Lydia, Aldasoro, Edelweiss, O'Brien, Ãine, Nolan, Maeve, McGovern, Cliona, Carroll, Ãine

“…Abstract Background The coronavirus 2019 pandemic placed unprecedented pressures on healthcare services and magnified ethical dilemmas related to how resources…”
Get full text

What is the purpose of clinical trial monitoring? by Love, Sharon B, Yorke-Edwards, Victoria, Ward, Elizabeth, Haydock, Rebecca, Keen, Katie, Biggs, Katie, Gopalakrishnan, Gosala, Marsh, Lucy, O'Sullivan, Lydia, Fox, Lisa, Payerne, Estelle, Hood, Kerenza, Meakin, Garry

“…The sources of information on clinical trial monitoring do not give information in an accessible language and do not give detailed guidance. In order to enable…”
Get full text

An enhanced participant information leaflet and multimedia intervention to improve the quality of informed consent to a randomised clinical trial enrolling people living with HIV and obesity: a protocol for a Study Within A Trial (SWAT) by O'Sullivan, Lydia, Savinelli, Stefano, O'Hare, Stephen, Holden, Sinéad, McHugh, Ciara, Mallon, Patrick, Doran, Peter

“…It is the investigator's responsibility to communicate the relevant information about a clinical trial to participants before they provide informed consent to…”
Get full text

Influence of Finishing Systems on Carcass Characteristics, Composition, and Fatty Acid Profile of Bison Bulls by Newton, Clay J., O'Sullivan, Lydia M., Underwood, Keith R., Grubbs, Judson K., Bakker, Christina E., Cammack, Kristi M., Dinh, Thu, Kruse, Carter, Blair, Amanda D.

“…The objective of this study was to determine the influence of grain- and grass-finishing systems on carcass characteristics of bison bulls and proximate and…”
Get full text

Preparing accessible and understandable clinical research participant information leaflets and consent forms: a set of guidelines from an expert consensus conference by Coleman, Eleanor, O'Sullivan, Lydia, Crowley, Rachel, Hanbidge, Moira, Driver, Seán, Kroll, Thilo, Kelly, Aoife, Nichol, Alistair, McCarthy, Orlaith, Sukumar, Prasanth, Doran, Peter

“…In line with Good Clinical Practice and the Declaration of Helsinki, it is the investigator's responsibility to ensure that research participants are…”
Get full text

Factors influencing the statistical planning, design, conduct, analysis and reporting of trials in health care: A systematic review by Zaki, Marina, O'Sullivan, Lydia, Devane, Declan, Segurado, Ricardo, McAuliffe, Eilish

“…Trials in health care are prospective human research studies designed to test the effectiveness and safety of health care interventions, such as medications,…”
Get full text

Contributory factors to the evolution of the concept and practice of informed consent in clinical research: A narrative review by O'Sullivan, Lydia, Crowley, Rachel, McAuliffe, Éilish, Doran, Peter

“…Informed consent can be defined as a freely-given decision or agreement following disclosure of relevant information. This review explores how legislation…”
Get full text

Product Yield and Color of Striploin and Sirloin Cuts Transported at Different Refrigerated Temperatures by Bakker, Christina E., O'Sullivan, Lydia M., Underwood, Keith R., Blair, Amanda D., Rode-Atkins, Heather R., Grubbs, J. Kyle

“…The objective of this study was to determine the impact of environmental temperature during subprimal transporton moisture loss, color, and tenderness. Cases…”
Get full text

A protocol for a systematic review investigating the factors influencing the statistical planning, design, conduct, analysis and reporting of clinical trials by Zaki, Marina, Galligan, Marie, O'Sullivan, Lydia, Devane, Declan, McAuliffe, Eilish

“…Clinical trials can be defined as prospective human research studies to test the effectiveness and safety of interventions, such as medications, surgeries,…”
Get full text

A protocol for a systematic review investigating the factors influencing the statistical planning, design, conduct, analysis and reporting of trials by Zaki, Marina, Galligan, Marie, O'Sullivan, Lydia, Devane, Declan, McAuliffe, Eilish

“…Trials can be defined as prospective human research studies to test the effectiveness and safety of interventions, such as medications, surgeries, medical…”
Get full text

Diagnostic accuracy of 18F Prostate Specific Membrane Antigen (PSMA) PET-CT radiotracers in staging and restaging of high-risk prostate cancer patients and patients with biochemical recurrence: protocol for an overview of reviews by Dullea, Andrew, O'Sullivan, Lydia, Carrigan, Marie, Ahern, Susan, McGarry, Maeve, O'Brien, Kirsty, Harrington, Patricia, Walsh, Kieran A., Smith, Susan M., Ryan, Máirín

“…Background: Correct staging and risk stratification is essential in ensuring prostate cancer patients are offered the most appropriate treatment. Interest has…”
Get full text

Ethical Considerations for safeguarding human participants in pandemic research: a rapid review protocol by O'Sullivan, Lydia, Killeen, Ronan P, Doran, Peter, Crowley, Rachel K

“…COVID-19 is a respiratory disease caused by a coronavirus, designated SARS-CoV-2, which is responsible for a global pandemic in 2020. Public interest in this…”
Get full text

Harmonising the human biobanking consent process: an Irish experience by O'Sullivan, Lydia, Carroll, Tomás P, Clarke, Niamh, Cooper, Sarah, Cullen, Ann, Gorman, Laura, McCann, Billy, Mee, Blánaid, Miller, Nicola, Murphy, Verena, Murray, Máiréad, O'Leary, Jackie, O'Toole, Sharon, Snapes, Emma, Bracken, Suzanne

“…Biobanks are repositories of human biological samples and data. They are an important component of clinical research in many disease areas and often represent…”
Get full text

Adherence with reporting of ethical standards in COVID-19 human studies: a rapid review by O'Sullivan, Lydia, Killeen, Ronan P, Doran, Peter, Crowley, Rachel K

“…Abstract Background Patients with COVID-19 may feel under pressure to participate in research during the pandemic. Safeguards to protect research participants…”
Get full text

An investigation into the factors affecting investigator-initiated trial start-up in Ireland by Leddy, Lauren, Sukumar, Prasanth, O’Sullivan, Lydia, Keane, Fionnuala, Devane, Declan, Doran, Peter

“…Abstract Background In common with many countries, Ireland has seen an increasing trend in the number of clinical trials conducted over the past few years…”
Get full text

An Overview of Post-Publication Peer Review by O’Sullivan, Lydia, Ma, Lai, Doran, Peter

“…The increasing demand for swift dissemination of research findings, combined with the drive towards transparency and open science has challenged the…”
Get full text