Search Results - "O'Sullivan, John D."
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A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation
Published in Drugs (New York, N.Y.) (01-04-2023)“…Chronic unresolving inflammation is emerging as a key underlying pathological feature of many if not most diseases ranging from autoimmune conditions to…”
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Identifying subtypes of mild cognitive impairment in Parkinson’s disease using cluster analysis
Published in Journal of neurology (01-11-2020)“…Introduction The concept of Mild Cognitive Impairment (MCI) in Parkinson’s disease (PD) has shown the potential for identifying at-risk dementia patients…”
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A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease
Published in Movement disorders (15-08-2010)“…Multiple lines of evidence point to mitochondrial oxidative stress as a potential pathogenic cause for Parkinson's disease (PD). MitoQ is a powerful…”
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Anxiety disorders are associated with verbal memory impairment in patients with Parkinson’s disease without dementia
Published in Journal of neurology (01-03-2022)“…Introduction Preliminary evidence has demonstrated a link between anxiety and memory impairment in Parkinson’s disease (PD). This study further investigated…”
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Semantic fluency deficits and associated brain activity in Parkinson’s disease with mild cognitive impairment
Published in Brain imaging and behavior (01-12-2022)“…People living with Parkinson’s disease (PD) with poor verbal fluency have an increased risk of developing dementia. This study examines the neural mechanisms…”
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Connected Patch Array Analysis Using the Characteristic Basis Function Method
Published in IEEE transactions on antennas and propagation (01-06-2011)“…The characteristic basis function method (CBFM) is extended to apply to efficient analysis of dual-polarized connected-patch arrays where neighboring patches…”
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Feasibility and Acceptability of a Videoconferencing CBT Intervention for Anxiety in People with Parkinson's Disease
Published in Clinical gerontologist (26-01-2024)“…In people with Parkinson's disease (PwPD), non-motor symptoms such as anxiety are common and have negative impacts on their quality of life. There are…”
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Punding in Parkinson's disease: Its relation to the dopamine dysregulation syndrome
Published in Movement disorders (01-04-2004)“…Punding is a term that was coined originally to describe complex prolonged, purposeless, and stereotyped behaviour in chronic amphetamine users. A structured…”
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Hippocampal resting‐state connectivity is associated with posterior‐cortical cognitive impairment in Parkinson's disease
Published in Brain and behavior (01-03-2024)“…Aim Frontal and posterior‐cortical cognitive subtypes in Parkinson's disease (PD) present with executive/attention and memory/visuospatial deficits,…”
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Longitudinal follow up of data-driven cognitive subtypes in Parkinson's disease
Published in Brain and behavior (01-10-2023)“…The dual syndrome hypothesis proposes that there are two cognitive subtypes in Parkinson's disease (PD): a frontal subtype with executive/attention impairment…”
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A Mutation in the Golgi Qb-SNARE Gene GOSR2 Causes Progressive Myoclonus Epilepsy with Early Ataxia
Published in American journal of human genetics (13-05-2011)“…The progressive myoclonus epilepsies (PMEs) are a group of predominantly recessive disorders that present with action myoclonus, tonic-clonic seizures, and…”
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How Well Do Caregivers Detect Depression and Anxiety in Patients With Parkinson Disease?
Published in Journal of geriatric psychiatry and neurology (01-09-2018)“…Depression and anxiety are prevalent in Parkinson disease (PD) yet underrecognized in clinical practice. Caregiver reports are frequently utilized to aid in…”
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Cognitive Behavior Therapy for Anxiety in Parkinson's Disease: Outcomes for Patients and Caregivers
Published in Clinical gerontologist (27-05-2017)“…Objective: Anxiety negatively impacts the quality of life of Parkinson's disease (PD) patients and caregivers. Despite high prevalence, there is a paucity of…”
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Profiling people with Parkinson's disease at risk of cognitive decline: Insights from PPMI and ICICLE‐PD data
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01-07-2024)“…Introduction A subset of people with Parkinson's disease (PD) develop dementia faster than others. We aimed to profile PD cognitive subtypes at risk of…”
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The effect of ageing on human lymphocyte subsets: comparison of males and females
Published in Immunity & ageing (16-03-2010)“…There is reported to be a decline in immune function and an alteration in the frequency of circulating lymphocytes with advancing age. There are also…”
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Improved receptive and expressive language abilities in nonfluent aphasic stroke patients after application of rTMS: An open protocol case series
Published in Brain stimulation (01-07-2012)“…Background Repetitive transcranial magnetic stimulation (rTMS) has been identified as a potentially valuable tool for the rehabilitation of language impairment…”
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Anxiety disorders in Parkinson's disease: Prevalence and risk factors
Published in Movement disorders (15-05-2010)Get full text
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Risk factors for idiopathic dystonia in Queensland, Australia
Published in Journal of clinical neuroscience (01-12-2014)“…Abstract It is currently hypothesised that a combination of genetic and environmental factors underlies the development of idiopathic isolated dystonia (IID)…”
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Characteristics of advanced Parkinson's disease patients seen in movement disorder clinics - Australian results from the cross-sectional OBSERVE study
Published in Clinical parkinsonism & related disorders (01-01-2021)“…To evaluate the proportion of Parkinson's disease (PD) patients identified as having advanced Parkinson's disease (APD) according to physician's judgement in…”
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Vertebrobasilar dissections: Case series comparing patients with and without dissecting aneurysms
Published in Journal of clinical neuroscience (01-11-2014)“…Abstract Vertebrobasilar dissections are being increasingly diagnosed due to better awareness and increased availability of modern imaging techniques of the…”
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