Search Results - "O'Sullivan, Brian"
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Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy
Published in JNCI : Journal of the National Cancer Institute (01-07-2019)“…Abstract Nasopharyngeal carcinoma (NPC) is a type of head and neck cancer with a distinctive regional and racial prevalence. It is associated with Epstein-Barr…”
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Cystic fibrosis
Published in The Lancet (British edition) (30-05-2009)“…Summary Cystic fibrosis is the most common lethal genetic disease in white populations. The outlook for patients with the disease has improved steadily over…”
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Head and neck cancers—major changes in the American Joint Committee on cancer eighth edition cancer staging manual
Published in CA: a cancer journal for clinicians (01-03-2017)“…Answer questions and earn CME/CNE The recently released eighth edition of the American Joint Committee on Cancer (AJCC) Staging Manual, Head and Neck Section,…”
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Unfinished Business in Classifying HPV-Positive Oropharyngeal Carcinoma: Identifying the Bad Apples in a Good Staging Barrel
Published in The oncologist (Dayton, Ohio) (03-02-2022)“…This commentary highlights three important findings in the study by Vijayvargiya et al, published in this journal, involving 9554 oropharyngeal cancer patients…”
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Bias and inconsistency in the estimation of tumour mutation burden
Published in BMC cancer (02-08-2022)“…Abstract Background Tumour mutation burden (TMB), defined as the number of somatic mutations per megabase within the sequenced region in the tumour sample, has…”
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Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a multicentre cohort study
Published in The lancet oncology (01-04-2016)“…Summary Background Human papillomavirus-related (HPV+) oropharyngeal cancer is a rapidly emerging disease with generally good prognosis. Many prognostic…”
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The TNM classification of malignant tumours—towards common understanding and reasonable expectations
Published in The lancet oncology (01-07-2017)“…[...]the universal use of the TNM classification has made it a subject of unreasonable expectation. To better define the principles of the TNM classification,…”
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Oligometastatic Head and Neck Cancer: Challenges and Perspectives
Published in Cancers (01-08-2022)“…A minority of patients with metastatic head and neck squamous cell carcinoma (HNSCC) present with oligometastatic disease. Oligometastasis not only reflects a…”
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Vulnerabilities of radiomic signature development: The need for safeguards
Published in Radiotherapy and oncology (01-01-2019)“…•Presented Safeguards ensure productive progress of the radiomic field.•Radiomic models and features should be tested to determine added prognostic and…”
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Selection of lymph node target volumes for definitive head and neck radiation therapy: a 2019 Update
Published in Radiotherapy and oncology (01-05-2019)“…•Updated proposal for the selection of nodal target volumes in definitive radiotherapy is provided.•Recommendations for both negative and positive neck are…”
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Global Consultation on Cancer Staging: promoting consistent understanding and use
Published in Nature reviews. Clinical oncology (01-12-2019)“…Disease burden is the most important determinant of survival in patients with cancer. This domain, reflected by the cancer stage and codified using the…”
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Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002)
Published in Journal of clinical oncology (20-03-2021)“…Reducing radiation treatment dose could improve the quality of life (QOL) of patients with good-risk human papillomavirus-associated oropharyngeal squamous…”
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Analysis of Margin Classification Systems for Assessing the Risk of Local Recurrence After Soft Tissue Sarcoma Resection
Published in Journal of clinical oncology (01-03-2018)“…Purpose To compare the ability of margin classification systems to determine local recurrence (LR) risk after soft tissue sarcoma (STS) resection. Methods Two…”
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Long-Term Late Toxicity, Quality of Life, and Emotional Distress in Patients With Nasopharyngeal Carcinoma Treated With Intensity Modulated Radiation Therapy
Published in International journal of radiation oncology, biology, physics (01-10-2018)“…To report long-term (>4 years) toxicity and quality of life (QoL) among patients with nasopharyngeal carcinoma (NPC) treated with intensity modulated radiation…”
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Expanding global access to radiotherapy
Published in The lancet oncology (01-09-2015)“…Summary Radiotherapy is a critical and inseparable component of comprehensive cancer treatment and care. For many of the most common cancers in low-income and…”
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How many billions is enough? Prioritizing profits over patients with cystic fibrosis
Published in Pediatric pulmonology (01-05-2023)Get full text
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Preoperative radiotherapy for extremity soft tissue sarcoma; past, present and future perspectives on dose fractionation regimens and combined modality strategies
Published in Radiotherapy and oncology (01-04-2016)“…Abstract Introduction: This critical review aims to summarize published data on limb sparing surgery for extremity soft tissue sarcoma in combination with…”
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Refining American Joint Committee on Cancer/Union for International Cancer Control TNM stage and prognostic groups for human papillomavirus-related oropharyngeal carcinomas
Published in Journal of clinical oncology (10-03-2015)“…To refine stage and prognostic group for human papillomavirus (HPV) -related nonmetastatic (M0) oropharyngeal cancer (OPC). All patients with nonmetastatic…”
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Critical Impact of Radiotherapy Protocol Compliance and Quality in the Treatment of Advanced Head and Neck Cancer: Results From TROG 02.02
Published in Journal of clinical oncology (20-06-2010)“…To report the impact of radiotherapy quality on outcome in a large international phase III trial evaluating radiotherapy with concurrent cisplatin plus…”
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Importance of Off-Label Options for Treating Serious Lung Diseases
Published in Annals of the American Thoracic Society (01-11-2016)Get full text
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