Search Results - "O'Shea, Callan"

Parsing the Functional Impact of Noncoding Genetic Variants in the Brain Epigenome by Powell, Samuel K., O’Shea, Callan, Brennand, Kristen J., Akbarian, Schahram

“…The heritability of common psychiatric disorders has motivated global efforts to identify risk-associated genetic variants and elucidate molecular pathways…”
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Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk by Powell, Samuel K., O’Shea, Callan, Townsley, Kayla, Prytkova, Iya, Dobrindt, Kristina, Elahi, Rahat, Iskhakova, Marina, Lambert, Tova, Valada, Aditi, Liao, Will, Ho, Seok-Man, Slesinger, Paul A., Huckins, Laura M., Akbarian, Schahram, Brennand, Kristen J.

“…Dopaminergic neurons are critical to movement, mood, addiction, and stress. Current techniques for generating dopaminergic neurons from human induced…”
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HIV integration in the human brain is linked to microglial activation and 3D genome remodeling by Plaza-Jennings, Amara L., Valada, Aditi, O’Shea, Callan, Iskhakova, Marina, Hu, Benxia, Javidfar, Behnam, Ben Hutta, Gabriella, Lambert, Tova Y., Murray, Jacinta, Kassim, Bibi, Chandrasekaran, Sandhya, Chen, Benjamin K., Morgello, Susan, Won, Hyejung, Akbarian, Schahram

“…To explore genome organization and function in the HIV-infected brain, we applied single-nuclei transcriptomics, cell-type-specific chromosomal conformation…”
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Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection by Dobrindt, Kristina, Hoagland, Daisy A., Seah, Carina, Kassim, Bibi, O'Shea, Callan P., Murphy, Aleta, Iskhakova, Marina, Fernando, Michael B., Powell, Samuel K., Deans, P.J. Michael, Javidfar, Ben, Peter, Cyril, Møller, Rasmus, Uhl, Skyler A., Garcia, Meilin Fernandez, Kimura, Masaki, Iwasawa, Kentaro, Crary, John F., Kotton, Darrell N., Takebe, Takanori, Huckins, Laura M., tenOever, Benjamin R., Akbarian, Schahram, Brennand, Kristen J.

“…The host response to SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, demonstrates significant interindividual variability. In addition to showing…”
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Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells by Powell, Samuel K, O'Shea, Callan P, Shannon, Sara Rose, Akbarian, Schahram, Brennand, Kristen J

“…Schizophrenia is a chronic and severe neuropsychiatric condition manifested by cognitive, emotional, affective, perceptual, and behavioral abnormalities…”
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19. GENETIC RISK ARCHITECTURE OF SCHIZOPHRENIA AND THREE-DIMENSIONAL CHROMATIN DYNAMICS ACROSS NEUROTRANSMITTER SYSTEMS by Powell, Samuel, O'Shea, Callan, Townsley, Kayla, Dobrindt, Kristina, Elahi, Rahat, Prytkova, Iya, Slesinger, Paul, Huckins, Laura, Akbarian, Schahram, Brennand, Kristen

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Parsing the Functional Impact of Non-Coding Genetic Variants in the Brain Epigenome by Powell, Samuel K., O’Shea, Callan, Brennand, Kristen J., Akbarian, Schahram

“…The heritability of common psychiatric disorders has motivated global efforts to identify risk-associated genetic variants and elucidate molecular pathways…”
Get full text