Search Results - "O'Rourke, Delia"

Mutations in ATRX , encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation by Higgs, Douglas R, Gibbons, Richard J, McDowell, Tarra L, Raman, Sundhya, O'Rourke, Delia M, Garrick, David, Ayyub, Helena

“…A goal of molecular genetics is to understand the relationship between basic nuclear processes, epigenetic changes and the numerous proteins that orchestrate…”
Get full text

Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans by Bishop, Tammie, Lau, Kah Weng, Epstein, Andrew C R, Kim, Stuart K, Jiang, Min, O'Rourke, Delia, Pugh, Christopher W, Gleadle, Jonathan M, Taylor, Martin S, Hodgkin, Jonathan, Ratcliffe, Peter J

“…The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated alpha subunits of…”
Get full text

Multiple Genes Affect Sensitivity of Caenorhabditis elegans to the Bacterial Pathogen Microbacterium nematophilum by Gravato-Nobre, Maria J, Nicholas, Hannah R, Nijland, Reindert, O'Rourke, Delia, Whittington, Deborah E, Yook, Karen J, Hodgkin, Jonathan

“…Interactions with bacteria play a major role in immune responses, ecology, and evolution of all animals, but they have been neglected until recently in the…”
Get full text

Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum by O'Rourke, Delia, Baban, Dilair, Demidova, Maria, Mott, Richard, Hodgkin, Jonathan

“…The interaction between the nematode Caenorhabditis elegans and a Gram-positive bacterial pathogen, Microbacterium nematophilum, provides a model for an innate…”
Get full text

Isolation and molecular identification of nematode surface mutants with resistance to bacterial pathogens by O’Rourke, Delia, Gravato-Nobre, Maria J, Stroud, Dave, Pritchett, Emily, Barker, Emily, Price, Rebecca L, Robinson, Sarah A, Spiro, Simon, Kuwabara, Patricia, Hodgkin, Jonathan

“…Abstract Numerous mutants of the nematode Caenorhabditis elegans with surface abnormalities have been isolated by utilizing their resistance to a variety of…”
Get full text

Lipodisqs for eukaryote lipidomics with retention of viability: Sensitivity and resistance to Leucobacter infection linked to C.elegans cuticle composition by Bada Juarez, Juan F., O’Rourke, Delia, Judge, Peter J., Liu, Li C., Hodgkin, Jonathan, Watts, Anthony

“…•SMA polymer is used extract surface lipids from C. elegans strains without loss of viability.•Infection-resistant C. elegans display differences in the lipid…”
Get full text

Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4) by Loer, Curtis M, Calvo, Ana C, Watschinger, Katrin, Werner-Felmayer, Gabriele, O'Rourke, Delia, Stroud, Dave, Tong, Amy, Gotenstein, Jennifer R, Chisholm, Andrew D, Hodgkin, Jonathan, Werner, Ernst R, Martinez, Aurora

“…Tetrahydrobiopterin (BH4) is the natural cofactor of several enzymes widely distributed among eukaryotes, including aromatic amino acid hydroxylases (AAAHs),…”
Get full text

Glycosylation genes expressed in seam cells determine complex surface properties and bacterial adhesion to the cuticle of Caenorhabditis elegans by Gravato-Nobre, Maria J, Stroud, Dave, O'Rourke, Delia, Darby, Creg, Hodgkin, Jonathan

“…The surface of the nematode Caenorhabditis elegans is poorly understood but critical for its interactions with the environment and with pathogens. We show here…”
Get full text

Caenorhabditis elegans bacterial pathogen resistant bus-4 mutants produce altered mucins by Parsons, Lisa M, Mizanur, Rahman M, Jankowska, Ewa, Hodgkin, Jonathan, O Rourke, Delia, Stroud, Dave, Ghosh, Salil, Cipollo, John F

“…Caenorabditis elegans bus-4 glycosyltransferase mutants are resistant to infection by Microbacterium nematophilum, Yersinia pestis and Yersinia…”
Get full text

The Core‐1 O‐glycans of Microbacterium nematophilum Resistant Caenorhabditis elegans bus‐4 mutants are altered by Rahman, Miznaur, Jankowska, Ewa, Hodgkin, Jonathan, O'Rourke, Delia, Stroud, David

“…Microbacterium nematophilum causes a cutaneous infection of the Caenorhabditis elegans hind gut initiated by adhesion to the rectum, anus and surrounding…”
Get full text

Caenorhabditis elegans Bacterial Pathogen Resistant bus-4 Mutants Produce Altered Mucins: e107250 by Parsons, Lisa M, Mizanur, Rahman M, Jankowska, Ewa, Hodgkin, Jonathan, O'Rourke, Delia, Stroud, Dave, Ghosh, Salil, Cipollo, John F

“…Caenorabditis elegans bus-4 glycosyltransferase mutants are resistant to infection by Microbacterium nematophilum, Yersinia pestis and Yersinia…”
Get full text

Point mutations in the herpes simplex virus type 1 Vmw110 RING finger helix affect activation of gene expression, viral growth, and interaction with PML-containing nuclear structures by Everett, R, O'Hare, P, O'Rourke, D, Barlow, P, Orr, A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

A C-terminal targeting signal controls differential compartmentalisation of Caenorhabditis elegans host cell factor (HCF) to the nucleus or mitochondria by Izeta, Ander, Malcomber, Sophie, O'Rourke, Delia, Hodgkin, Jonathan, O'Hare, Peter

“…HCF-1 (host cell factor 1) is a human protein originally identified as a component of the VP16 transcription complex. A related protein HCF-2 is also present…”
Get full text

Examination of determinants for intranuclear localization and transactivation within the RING finger of herpes simplex virus type 1 IE110k protein by O'Rourke, D, Elliott, G, Papworth, M, Everett, R, O'Hare, P

“…D O'Rourke, G Elliott, M Papworth, R Everett and P O'Hare Marie Curie Research Institute, The Chart, Oxted, Surrey, UK. The herpesvirus regulatory protein…”
Get full text