Search Results - "O'Riordan, J."

The gut microbiome in neurological disorders by Cryan, John F, O'Riordan, Kenneth J, Sandhu, Kiran, Peterson, Veronica, Dinan, Timothy G

“…Research into the role of the gut microbiome in modulating brain function has rapidly increased over the past 10 years, albeit chiefly in animal models…”
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Microbiota-Gut-Brain Axis: New Therapeutic Opportunities by Long-Smith, Caitríona, O'Riordan, Kenneth J, Clarke, Gerard, Stanton, Catherine, Dinan, Timothy G, Cryan, John F

“…The traditional fields of pharmacology and toxicology are beginning to consider the substantial impact our gut microbiota has on host physiology. The…”
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The Microbiota-Gut-Brain Axis by Cryan, John F, O'Riordan, Kenneth J, Cowan, Caitlin S M, Sandhu, Kiran V, Bastiaanssen, Thomaz F S, Boehme, Marcus, Codagnone, Martin G, Cussotto, Sofia, Fulling, Christine, Golubeva, Anna V, Guzzetta, Katherine E, Jaggar, Minal, Long-Smith, Caitriona M, Lyte, Joshua M, Martin, Jason A, Molinero-Perez, Alicia, Moloney, Gerard, Morelli, Emanuela, Morillas, Enrique, O'Connor, Rory, Cruz-Pereira, Joana S, Peterson, Veronica L, Rea, Kieran, Ritz, Nathaniel L, Sherwin, Eoin, Spichak, Simon, Teichman, Emily M, van de Wouw, Marcel, Ventura-Silva, Ana Paula, Wallace-Fitzsimons, Shauna E, Hyland, Niall, Clarke, Gerard, Dinan, Timothy G

“…The importance of the gut-brain axis in maintaining homeostasis has long been appreciated. However, the past 15 yr have seen the emergence of the microbiota…”
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Microbial memories: Sex‐dependent impact of the gut microbiome on hippocampal plasticity by Darch, Henry T., Collins, Michael K., O’Riordan, Kenneth J., Cryan, John F.

“…Germ‐free rodents, raised in the absence of a measurable gut microbiome, have been a key model to study the microbiome‐gut‐brain axis. Germ‐free mice exhibit…”
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When Rhythms Meet the Blues: Circadian Interactions with the Microbiota-Gut-Brain Axis by Teichman, Emily M., O’Riordan, Kenneth J., Gahan, Cormac G.M., Dinan, Timothy G., Cryan, John F.

“…The microbiota-gut-brain axis encompasses a bidirectional mode of communication between the microorganisms residing in our gut, and our brain function and…”
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Microbiota and sleep: awakening the gut feeling by Sen, Paromita, Molinero-Perez, Alicia, O’Riordan, Kenneth J., McCafferty, Cian P., O’Halloran, Ken D., Cryan, John F.

“…Various lifestyle and environmental factors are known to influence sleep. Increasingly, evidence points to a role for the microbiota in regulating brain and…”
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Towards a psychobiotic therapy for depression: Bifidobacterium breve CCFM1025 reverses chronic stress-induced depressive symptoms and gut microbial abnormalities in mice by Tian, Peijun, O'Riordan, Kenneth J., Lee, Yuan-kun, Wang, Gang, Zhao, Jianxin, Zhang, Hao, Cryan, John F., Chen, Wei

“…Accumulating evidence points to an association between gut microbial abnormalities and depression disorder. The microbiota-gut-brain axis is an emerging target…”
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Incidence and prevalence of multiple sclerosis in the UK 1990–2010: a descriptive study in the General Practice Research Database by Mackenzie, I S, Morant, S V, Bloomfield, G A, MacDonald, T M, O'Riordan, J

“…Objectives To estimate the incidence and prevalence of multiple sclerosis (MS) by age and describe secular trends and geographic variations within the UK over…”
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Meta‐analysis of the effect of extending the interval after long‐course chemoradiotherapy before surgery in locally advanced rectal cancer by Ryan, É. J., O'Sullivan, D. P., Kelly, M. E., Syed, A. Z., Neary, P. C., O'Connell, P. R., Kavanagh, D. O., Winter, D. C., O'Riordan, J. M.

“…Background The current standard of care in locally advanced rectal cancer (LARC) is neoadjuvant long‐course chemoradiotherapy (nCRT) followed by total…”
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Hepatitis E and blood donation safety in selected European countries: a shift to screening? by Domanović, Dragoslav, Tedder, Richard, Blümel, Johannes, Zaaijer, Hans, Gallian, Pierre, Niederhauser, Christoph, Sauleda Oliveras, Silvia, O'Riordan, Joan, Boland, Fiona, Harritshøj, Lene, Nascimento, Maria São José, Ciccaglione, Anna Rita, Politis, Constatina, Adlhoch, Cornelia, Flan, Benoit, Oualikene-Gonin, Wahiba, Rautmann, Guy, Strengers, Paul, Hewitt, Patricia

“…The public health implications of hepatitis E virus (HEV) in Europe have changed due to increasing numbers of hepatitis E cases and recent reports of chronic,…”
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Physiological activation of mGlu5 receptors supports the ion channel function of NMDA receptors in hippocampal LTD induction in vivo by O’Riordan, Kenneth J., Hu, Neng-Wei, Rowan, Michael J.

“…Synaptic long-term depression (LTD) is believed to underlie critical mnemonic processes in the adult hippocampus. The roles of the metabotropic and ionotropic…”
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Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography by Wolff, Alexander M., Nango, Eriko, Young, Iris D., Brewster, Aaron S., Kubo, Minoru, Nomura, Takashi, Sugahara, Michihiro, Owada, Shigeki, Barad, Benjamin A., Ito, Kazutaka, Bhowmick, Asmit, Carbajo, Sergio, Hino, Tomoya, Holton, James M., Im, Dohyun, O’Riordan, Lee J., Tanaka, Tomoyuki, Tanaka, Rie, Sierra, Raymond G., Yumoto, Fumiaki, Tono, Kensuke, Iwata, So, Sauter, Nicholas K., Fraser, James S., Thompson, Michael C.

“…Understanding and controlling protein motion at atomic resolution is a hallmark challenge for structural biologists and protein engineers because…”
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Metabolic regulation of neuronal plasticity by the energy sensor AMPK by Potter, Wyatt B, O'Riordan, Kenneth J, Barnett, David, Osting, Susan M K, Wagoner, Matthew, Burger, Corinna, Roopra, Avtar

“…Long Term Potentiation (LTP) is a leading candidate mechanism for learning and memory and is also thought to play a role in the progression of seizures to…”
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Collating evidence to support the validation of a simulated laparotomy incision and closure-training model by Roche, Adam F., Kavanagh, Dara, McCawley, Niamh, O'Riordan, J.M., Cahir, Caitriona, Toale, Conor, O'Keeffe, Dara, Lawler, Tim, Condron, Claire M.

“…It is essential to evaluate the functionality of surgical simulation models, in order to determine whether they perform as intended. In this study, we assessed…”
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Regulation of Histone Acetylation during Memory Formation in the Hippocampus by Levenson, Jonathan M., O'Riordan, Kenneth J., Brown, Karen D., Trinh, Mimi A., Molfese, David L., Sweatt, J. David

“…Formation of long term memory begins with the activation of many disparate signaling pathways that ultimately impinge on the cellular mechanisms regulating…”
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Aß Facilitates LTD at Schaffer Collateral Synapses Preferentially in the Left Hippocampus by O’Riordan, Kenneth J., Hu, Neng-Wei, Rowan, Michael J.

“…Promotion of long-term depression (LTD) mechanisms by synaptotoxic soluble oligomers of amyloid-β (Aß) has been proposed to underlie synaptic dysfunction in…”
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Improving signal strength in serial crystallography with DIALS geometry refinement by Brewster, Aaron S., Waterman, David G., Parkhurst, James M., Gildea, Richard J., Young, Iris D., O'Riordan, Lee J., Yano, Junko, Winter, Graeme, Evans, Gwyndaf, Sauter, Nicholas K.

“…The DIALS diffraction‐modeling software package has been applied to serial crystallography data. Diffraction modeling is an exercise in determining the…”
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A hybrid classical-quantum workflow for natural language processing by O'Riordan, Lee J, Doyle, Myles, Baruffa, Fabio, Kannan, Venkatesh

“…Natural language processing (NLP) problems are ubiquitous in classical computing, where they often require significant computational resources to infer…”
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Potent anti-seizure effects of D-leucine by Hartman, Adam L, Santos, Polan, O'Riordan, Kenneth J, Stafstrom, Carl E, Marie Hardwick, J

“…Abstract There are no effective treatments for millions of patients with intractable epilepsy. High-fat ketogenic diets may provide significant clinical…”
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Ruthenium-Catalyzed Isomerization of Terminal Olefins: Applications to Synthesis by Donohoe, Timothy J, O'Riordan, Timothy J.C, Rosa, Carla P

“…In, out, olefin about: A ruthenium hydride complex derived from the Grubbs second‐generation metathesis catalyst has proven to be an efficient catalyst for the…”
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