Search Results - "O'ROURKE, P. P"

Reasons for Testing Mediation in the Absence of an Intervention Effect: A Research Imperative in Prevention and Intervention Research by O'Rourke, Holly P, MacKinnon, David P

“…Mediation models are used in prevention and intervention research to assess the mechanisms by which interventions influence outcomes. However, researchers may…”
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Statistical properties of four effect-size measures for mediation models by Miočević, Milica, O’Rourke, Holly P., MacKinnon, David P., Brown, Hendricks C.

“…This project examined the performance of classical and Bayesian estimators of four effect size measures for the indirect effect in a single-mediator model and…”
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When the test of mediation is more powerful than the test of the total effect by O’Rourke, Holly P., MacKinnon, David P.

“…Although previous research has studied power in mediation models, the extent to which the inclusion of a mediator will increase power has not been…”
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Indoor hospital air and the impact of ventilation on bioaerosols: a systematic review by Stockwell, R.E., Ballard, E.L., O'Rourke, P., Knibbs, L.D., Morawska, L., Bell, S.C.

“…Healthcare-acquired infections (HAIs) continue to persist in hospitals, despite the use of increasingly strict infection-control precautions. Opportunistic…”
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Removal versus retention of asymptomatic third molars in mandibular angle fractures: a randomized controlled trial by McNamara, Z, Findlay, G, O’Rourke, P, Batstone, M

“…Abstract The treatment dilemma provided by asymptomatic third molars in mandibular angle fractures remains controversial. This prospective randomized…”
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Dynamic change meets mechanisms of change: Examining mediators in the latent change score framework by Hilley, Chanler D., O’Rourke, Holly P.

“…Researchers in behavioral sciences are often interested in longitudinal behavior change outcomes and the mechanisms that influence changes in these outcomes…”
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Time since intercourse (TSI) data from a large-scale casework study of penile–vaginal penetration allegations using Sperm Elution by Owers, R., Davidson, G., McDonald, A., Morgan, R., O’Rourke, P.

“…•Improved semen recovery and DNA profiling results using Sperm Elution™.•Comparison of time since intercourse data using different swab elution…”
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53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis by Fong, Chii Shyang, Mazo, Gregory, Das, Tuhin, Goodman, Joshua, Kim, Minhee, O'Rourke, Brian P, Izquierdo, Denisse, Tsou, Meng-Fu Bryan

“…Mitosis occurs efficiently, but when it is disturbed or delayed, p53-dependent cell death or senescence is often triggered after mitotic exit. To characterize…”
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Mid-Term Effects of Selective Denervation Surgery on Facial Symmetry in Patients with Nonflaccid Facial Paralysis: Intermediate Follow-Up of Rest and Smile Symmetry by Varman, Rahul, O'Rourke, Samuel P, Nix, Evan, Miller, Matthew Q

“…Although selective denervation (SD) improves clinician-graded, objective, and patient-reported smile symmetry, changes in resting symmetry have not been…”
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Genomic Medicine: Too Great Expectations? by O'Rourke, P P

“…As advances in genomic medicine have captured the interest and enthusiasm of the public, an unintended consequence has been the creation of unrealistic…”
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Exercise for overweight or obesity by Shaw, K, Gennat, H, O'Rourke, P, Del Mar, C

“…Clinical trials have shown that exercise in adults with overweight or obesity can reduce bodyweight. There has been no quantitative systematic review of this…”
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Suppression of murine osteoarthritis by 4‐methylumbelliferone by Tsuchiya, Saho, Ohashi, Yoshifumi, Ishizuka, Shinya, Ishiguro, Naoki, O'Rourke, Dorcas P., Knudson, Cheryl B., Knudson, Warren

“…ABSTRACT Using in vitro models, we previously reported that 4‐methylumbelliferone (4‐MU) blocked many of the pro‐catabolic features of activated chondrocytes…”
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Structure–Activity Relationship Studies of the Tricyclic Indoline Resistance-Modifying Agent by Chang, Le, Podoll, Jessica D, Wang, Wei, Walls, Shane, O’Rourke, Courtney P, Wang, Xiang

“…Previously we discovered a tricyclic indoline, N-[2-(6-bromo-4-methylidene-2,3,4,4a,9,9a-hexahydro-1H-carbazol-4a-yl)­ethyl]-4-chlorobenzene-1-sulfonamide (1,…”
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The Final Rule: When the Rubber Meets the Road by O'Rourke, P. Pearl

“…The Common Rule originally issued in 1991 and last amended in 2005 is scheduled to be replaced on January 19, 2018 by a revised Common Rule (the final rule)…”
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The Importance of Time Metric Precision When Implementing Bivariate Latent Change Score Models by O'Rourke, Holly P., Fine, Kimberly L., Grimm, Kevin J., MacKinnon, David P.

“…The literature on latent change score models does not discuss the importance of using a precise time metric when structuring the data. This study examined the…”
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Development of a mimotope vaccine targeting the Staphylococcus aureus quorum sensing pathway by O'Rourke, John P, Daly, Seth M, Triplett, Kathleen D, Peabody, David, Chackerian, Bryce, Hall, Pamela R

“…A major hurdle in vaccine development is the difficulty in identifying relevant target epitopes and then presenting them to the immune system in a context that…”
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Ethical and Practical Guidelines for Reporting Genetic Research Results to Study Participants: Updated Guidelines From a National Heart, Lung, and Blood Institute Working Group by Fabsitz, Richard R, McGuire, Amy, Sharp, Richard R, Puggal, Mona, Beskow, Laura M, Biesecker, Leslie G, Bookman, Ebony, Burke, Wylie, Burchard, Esteban Gonzalez, Church, George, Clayton, Ellen Wright, Eckfeldt, John H, Fernandez, Conrad V, Fisher, Rebecca, Fullerton, Stephanie M, Gabriel, Stacey, Gachupin, Francine, James, Cynthia, Jarvik, Gail P, Kittles, Rick, Leib, Jennifer R, OʼDonnell, Christopher, OʼRourke, P Pearl, Rodriguez, Laura Lyman, Schully, Sheri D, Shuldiner, Alan R, Sze, Rebecca K.F, Thakuria, Joseph V, Wolf, Susan M, Burke, Gregory L

“…In January 2009, the National Heart, Lung, and Blood Institute convened a 28-member multidisciplinary Working Group to update the recommendations of a 2004…”
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Psychological interventions for overweight or obesity by Shaw, K, O'Rourke, P, Del Mar, C, Kenardy, J

“…Overweight and obesity are global health problems which are increasing throughout the industrialised world. If left unchecked, they will continue to contribute…”
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Clarifying the Ethics and Oversight of Chimeric Research by Johnston, Josephine, Hyun, Insoo, Neuhaus, Carolyn P., Maschke, Karen J., Marshall, Patricia, Craig, Kaitlynn P., Matthews, Margaret M., Drolet, Kara, Greely, Henry T., Hill, Lori R., Hinterberger, Amy, Hurley, Elisa A., Kesterson, Robert, Kimmelman, Jonathan, King, Nancy M. P., Lopes, Melissa J., O'Rourke, P. Pearl, Parent, Brendan, Peckman, Steven, Piotrowska, Monika, Schwarz, May, Sebo, Jeff, Stodgell, Chris, Streiffer, Robert, Wilkerson, Amy

“…This article is the lead piece in a special report that presents the results of a bioethical investigation into chimeric research, which involves the insertion…”
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Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly by Friederich, Marisa W, Erdogan, Alican J, Coughlin, 2nd, Curtis R, Elos, Mihret T, Jiang, Hua, O'Rourke, Courtney P, Lovell, Mark A, Wartchow, Eric, Gowan, Katherine, Chatfield, Kathryn C, Chick, Wallace S, Spector, Elaine B, Van Hove, Johan L K, Riemer, Jan

“…An infant presented with fatal infantile lactic acidosis and cardiomyopathy, and was found to have profoundly decreased activity of respiratory chain complex I…”
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