Search Results - "O'ROURKE, Matthew"

Exploring the Magnetic Properties of the Largest Single-Molecule Magnets by Schurkus, Henry F, Chen, Dianteng, O’Rourke, Matthew J, Cheng, Hai-Ping, Chan, Garnet Kin-Lic

“…The giant {Mn70} and {Mn84} wheels are the largest nuclearity single-molecule magnets synthesized to date, and understanding their magnetic properties poses a…”
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Sensitivity and Specificity of a Single Emergency Department Measurement of Urinary Neutrophil Gelatinase-Associated Lipocalin for Diagnosing Acute Kidney Injury by NICKOLAS, Thomas L, O'ROURKE, Matthew J, DEVARAJAN, Prasad, BARASCH, Jonathan, JUN YANG, SISE, Meghan E, CANETTA, Pietro A, BARASCH, Nicholas, BUCHEN, Charles, KHAN, Faris, MORI, Kiyoshi, GIGLIO, James

“…A single serum creatinine measurement cannot distinguish acute kidney injury from chronic kidney disease or prerenal azotemia. To test the sensitivity and…”
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Analysis of formalin-fixed, paraffin-embedded (FFPE) tissue via proteomic techniques and misconceptions of antigen retrieval by O'Rourke, Matthew B, Padula, Matthew P

“…Since emerging in the late 19(th) century, formaldehyde fixation has become a standard method for preservation of tissues from clinical samples. The advantage…”
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The quest for improved reproducibility in MALDI mass spectrometry by O'Rourke, Matthew B., Djordjevic, Steven P., Padula, Matthew P.

“…Reproducibility has been one of the biggest hurdles faced when attempting to develop quantitative protocols for MALDI mass spectrometry. The heterogeneous…”
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An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis by Roediger, Ben, Lee, Quintin, Tikoo, Shweta, Cobbin, Joanna C.A., Henderson, James M., Jormakka, Mika, O’Rourke, Matthew B., Padula, Matthew P., Pinello, Natalia, Henry, Marisa, Wynne, Maria, Santagostino, Sara F., Brayton, Cory F., Rasmussen, Lorna, Lisowski, Leszek, Tay, Szun S., Harris, David C., Bertram, John F., Dowling, John P., Bertolino, Patrick, Lai, Jack H., Wu, Wengen, Bachovchin, William W., Wong, Justin J.-L., Gorrell, Mark D., Shaban, Babak, Holmes, Edward C., Jolly, Christopher J., Monette, Sébastien, Weninger, Wolfgang

“…The occurrence of a spontaneous nephropathy with intranuclear inclusions in laboratory mice has puzzled pathologists for over 4 decades, because its etiology…”
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Matrix phase fractionation: Investigating the compromise between dynamic range of analyte extraction and spatial resolution in mass spectrometry imaging by O’Rourke, Matthew B., Viengkhou, Barney, Smith, Caine C., Sonderegger, Lorenz, Padula, Matthew P., Sutherland, Greg T., Hofer, Markus J., Crossett, Ben

“…Rationale Matrix‐assisted laser desorption ionisation with mass spectrometry imaging (MSI) has seen rapid development in recent years and as such is becoming…”
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Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys by Lee, Quintin, Padula, Matthew P, Pinello, Natalia, Williams, Simon H, O'Rourke, Matthew B, Fumagalli, Marcilio Jorge, Orkin, Joseph D, Song, Renhua, Shaban, Babak, Brenner, Ori, Pimanda, John E, Weninger, Wolfgang, Souza, William Marciel de, Melin, Amanda D, Wong, Justin J-L, Crim, Marcus J, Monette, Sébastien, Roediger, Ben, Jolly, Christopher J

“…Mouse kidney parvovirus (MKPV) is a member of the provisional genus Chapparvovirus that causes renal disease in immune-compromised mice, with a disease course…”
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Data independent acquisition of plasma biomarkers of response to neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma by O'Rourke, Matthew B., Sahni, Sumit, Samra, Jaswinder, Mittal, Anubhav, Molloy, Mark P.

“…The detection of disease-related plasma biomarkers has challenged the proteomic community for years. Attractive features for plasma proteomics includes the…”
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Quantitative Proteomic Profiling of Small Molecule Treated Mesenchymal Stem Cells Using Chemical Probes by Santos, Jerran, Dolai, Sibasish, O'Rourke, Matthew B, Liu, Fei, Padula, Matthew P, Molloy, Mark P, Milthorpe, Bruce K

“…The differentiation of human adipose derived stem cells toward a neural phenotype by small molecules has been a vogue topic in the last decade. The…”
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An Inexpensive, simple calibration method for MALDI TOF/TOF systems by O'Rourke, Matthew B., Padula, Matthew P.

“…The array of analytes that can be measured by MADLI MS has created an equally vast range of calibration mixtures. The inherent problem with this is that…”
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Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics[S] by Zhang, Hui Emma, Hamson, Elizabeth J., Koczorowska, Maria Magdalena, Tholen, Stefan, Chowdhury, Sumaiya, Bailey, Charles G., Lay, Angelina J., Twigg, Stephen M., Lee, Quintin, Roediger, Ben, Biniossek, Martin L., O'Rourke, Matthew B., McCaughan, Geoffrey W., Keane, Fiona M., Schilling, Oliver, Gorrell, Mark D.

“…Fibroblast activation protein-α (FAP) can hydrolyze the post-proline bond. We identified endogenous substrates of FAP in fibroblasts that were previously naive…”
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Reusing Peptide Spectral Reference Libraries to Discover Putative Plasma Biomarkers of Response to Cancer Chemotherapy by O'Rourke, Matthew B, Hansbro, Philip P, Molloy, Mark P

“…Biofluids such as blood plasma are rich reservoirs of potential biomarkers for disease diagnosis, prognosis, and prediction of treatment response. However,…”
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A non-instrument-based method for the analysis of formalin-fixed paraffin-embedded human spinal cord via matrix-assisted laser desorption/ionisation imaging mass spectrometry by O'Rourke, Matthew B., Djordjevic, Steven P., Padula, Matthew P.

“…Rationale This paper, in conjunction with a work published earlier this year by O'Rourke et al., aims to provide a comprehensive set of protocols for the…”
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Optimal Preparation of Formalin Fixed Samples for Peptide Based Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Workflows by O'Rourke, Matthew B, Padula, Matthew P, Smith, Caine, Youssef, Priscilla, Cordwell, Stuart, Witting, Paul, Sutherland, Greg, Crossett, Ben

“…The use of matrix-assisted laser desorption/ionization, mass spectrometry imaging (MALDI MSI) has rapidly expanded, since this technique analyzes a host of…”
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Higher Mass Accuracy MALDI-TOF/TOF Lipid Imaging of Human Brain Tissue in Alzheimer's Disease by O'Rourke, Matthew B, Smith, Caine C, De La Monte, Suzanne M, Sutherland, Greg T, Padula, Matthew P

“…Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) is a well-established technique for elucidating the location and relative…”
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Optimised plasma sample preparation and LC‐MS analysis to support large‐scale proteomic analysis of clinical trial specimens: Application to the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) trial by O'Rourke, Matthew B., Januszewski, Andrzej S., Sullivan, David R., Lengyel, Imre, Stewart, Alan J., Arya, Swati, Ma, Ronald C., Galande, Sanjeev, Hardikar, Anandwardhan A., Joglekar, Mugdha V., Keech, Anthony C., Jenkins, Alicia J., Molloy, Mark P.

“…Purpose Robust, affordable plasma proteomic biomarker workflows are needed for large‐scale clinical studies. We evaluated aspects of sample preparation to…”
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A new standard of visual data representation for imaging mass spectrometry by O'Rourke, Matthew B., Padula, Matthew P.

“…Purpose MALDI imaging MS (IMS) is principally used for cancer diagnostics. In our own experience with publishing IMS data, we have been requested to modify our…”
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Determining eigenstates and thermal states on a quantum computer using quantum imaginary time evolution by Motta, Mario, Sun, Chong, Tan, Adrian T. K., O’Rourke, Matthew J., Ye, Erika, Minnich, Austin J., Brandão, Fernando G. S. L., Chan, Garnet Kin-Lic

“…The accurate computation of Hamiltonian ground, excited and thermal states on quantum computers stands to impact many problems in the physical and computer…”
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A versatile cost-effective method for the analysis of fresh frozen tissue sections via matrix-assisted laser desorption/ionisation imaging mass spectrometry by O'Rourke, Matthew B., Raymond, Benjamin B. A., Djordjevic, Steven P., Padula, Matthew P.

“…Rationale There are currently multiple methods available for the preparation of fresh frozen tissue samples for analysis via matrix‐assisted laser…”
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Entanglement in the quantum phases of an unfrustrated Rydberg atom array by O’Rourke, Matthew J., Chan, Garnet Kin-Lic

“…Recent experimental advances have stimulated interest in the use of large, two-dimensional arrays of Rydberg atoms as a platform for quantum information…”
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