Search Results - "O'REILLY, M. M"

Rivaroxaban for Thromboprophylaxis in High-Risk Ambulatory Patients with Cancer by Khorana, Alok A, Soff, Gerald A, Kakkar, Ajay K, Vadhan-Raj, Saroj, Riess, Hanno, Wun, Ted, Streiff, Michael B, Garcia, David A, Liebman, Howard A, Belani, Chandra P, O’Reilly, Eileen M, Patel, Jai N, Yimer, Habte A, Wildgoose, Peter, Burton, Paul, Vijapurkar, Ujjwala, Kaul, Simrati, Eikelboom, John, McBane, Robert, Bauer, Kenneth A, Kuderer, Nicole M, Lyman, Gary H

“…A placebo-controlled trial assessed the efficacy of rivaroxaban to prevent venous thrombosis in patients with cancer at high risk for thrombosis. The…”
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Widespread loss of lake ice around the Northern Hemisphere in a warming world by Sharma, Sapna, Blagrave, Kevin, Magnuson, John J., O’Reilly, Catherine M., Oliver, Samantha, Batt, Ryan D., Magee, Madeline R., Straile, Dietmar, Weyhenmeyer, Gesa A., Winslow, Luke, Woolway, R. Iestyn

“…Ice provides a range of ecosystem services—including fish harvest 1 , cultural traditions 2 , transportation 3 , recreation 4 and regulation of the…”
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Preoperative Treatment of Locally Advanced Rectal Cancer by Schrag, Deborah, Shi, Qian, Weiser, Martin R., Gollub, Marc J., Saltz, Leonard B., Musher, Benjamin L., Goldberg, Joel, Al Baghdadi, Tareq, Goodman, Karyn A., McWilliams, Robert R., Farma, Jeffrey M., George, Thomas J., Kennecke, Hagen F., Shergill, Ardaman, Montemurro, Michael, Nelson, Garth D., Colgrove, Brian, Gordon, Vallerie, Venook, Alan P., O’Reilly, Eileen M., Meyerhardt, Jeffrey A., Dueck, Amylou C., Basch, Ethan, Chang, George J., Mamon, Harvey J.

“…In a trial comparing preoperative chemoradiotherapy and FOLFOX in patients with rectal cancer undergoing sphincter-sparing surgery, 5-year disease-free…”
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Neuromas as the cause of pain in the residual limbs of amputees. An ultrasound study by O'Reilly, M.A.R, O'Reilly, P.M.R, Sheahan, J.N, Sullivan, J, O'Reilly, H.M, O'Reilly, M.J

“…Aim To explore the morphology of neuromas and to determine the differences, if any, between asymptomatic and symptomatic neuromas using ultrasound. Materials…”
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Ultrasound-responsive droplets for therapy: A review by Lea-Banks, H., O'Reilly, M.A., Hynynen, K.

“…The last two decades have seen the development of acoustically activated droplets, also known as phase-change emulsions, from a diagnostic tool to a…”
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Pancreatic cancer—A disease in need: Optimizing and integrating supportive care by Moffat, Gordon T., Epstein, Andrew S., O'Reilly, Eileen M.

“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy that continues to be challenging to treat. PDAC has the lowest 5‐year relative survival…”
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Atlantic Diabetes in Pregnancy (DIP): the prevalence and outcomes of gestational diabetes mellitus using new diagnostic criteria by O’Sullivan, E. P., Avalos, G., O’Reilly, M., Dennedy, M. C., Gaffney, G., Dunne, F.

“…Aims/hypothesis New diagnostic criteria for gestational diabetes mellitus (GDM) have recently been published. We wished to evaluate what impact these new…”
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Tumour response to TRK inhibition in a patient with pancreatic adenocarcinoma harbouring an NTRK gene fusion by O'Reilly, E M, Hechtman, J F

“…Although rare, NTRK gene fusions are known to be oncogenic drivers in pancreatic ductal adenocarcinoma (PDAC). We report the response of a metastatic…”
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Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations by Hu, Zishuo I, Shia, Jinru, Stadler, Zsofia K, Varghese, Anna M, Capanu, Marinela, Salo-Mullen, Erin, Lowery, Maeve A, Diaz, Jr, Luis A, Mandelker, Diana, Yu, Kenneth H, Zervoudakis, Alice, Kelsen, David P, Iacobuzio-Donahue, Christine A, Klimstra, David S, Saltz, Leonard B, Sahin, Ibrahim H, O'Reilly, Eileen M

“…Immune checkpoint inhibition has been shown to generate profound and durable responses in mismatch repair deficient (MMR-D) solid tumors and has elicited…”
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Perspectives on Euler angle singularities, gimbal lock, and the orthogonality of applied forces and applied moments by Hemingway, Evan G., O’Reilly, Oliver M.

“…Coordinate singularities and gimbal lock are two phenomena that present themselves in models for the dynamics of mechanical systems. The former phenomenon…”
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Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer by Rojas, Luis A., Sethna, Zachary, Soares, Kevin C., Olcese, Cristina, Pang, Nan, Patterson, Erin, Lihm, Jayon, Ceglia, Nicholas, Guasp, Pablo, Chu, Alexander, Yu, Rebecca, Chandra, Adrienne Kaya, Waters, Theresa, Ruan, Jennifer, Amisaki, Masataka, Zebboudj, Abderezak, Odgerel, Zagaa, Payne, George, Derhovanessian, Evelyna, Müller, Felicitas, Rhee, Ina, Yadav, Mahesh, Dobrin, Anton, Sadelain, Michel, Łuksza, Marta, Cohen, Noah, Tang, Laura, Basturk, Olca, Gönen, Mithat, Katz, Seth, Do, Richard Kinh, Epstein, Andrew S., Momtaz, Parisa, Park, Wungki, Sugarman, Ryan, Varghese, Anna M., Won, Elizabeth, Desai, Avni, Wei, Alice C., D’Angelica, Michael I., Kingham, T. Peter, Mellman, Ira, Merghoub, Taha, Wolchok, Jedd D., Sahin, Ugur, Türeci, Özlem, Greenbaum, Benjamin D., Jarnagin, William R., Drebin, Jeffrey, O’Reilly, Eileen M., Balachandran, Vinod P.

“…Pancreatic ductal adenocarcinoma (PDAC) is lethal in 88% of patients 1 , yet harbours mutation-derived T cell neoantigens that are suitable for vaccines 2 , 3…”
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Increased winter drownings in ice-covered regions with warmer winters by Sharma, Sapna, Blagrave, Kevin, Watson, Simon R, O'Reilly, Catherine M, Batt, Ryan, Magnuson, John J, Clemens, Tessa, Denfeld, Blaize A, Flaim, Giovanna, Grinberga, Laura, Hori, Yukari, Laas, Alo, Knoll, Lesley B, Straile, Dietmar, Takamura, Noriko, Weyhenmeyer, Gesa A

“…Winter activities on ice are culturally important for many countries, yet they constitute a high safety risk depending upon the stability of the ice. Because…”
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Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial by Meyerhardt, Jeffrey A, Shi, Qian, Fuchs, Charles S, Meyer, Jeffrey, Niedzwiecki, Donna, Zemla, Tyler, Kumthekar, Priya, Guthrie, Katherine A, Couture, Felix, Kuebler, Philip, Bendell, Johanna C, Kumar, Pankaj, Lewis, Dequincy, Tan, Benjamin, Bertagnolli, Monica, Grothey, Axel, Hochster, Howard S, Goldberg, Richard M, Venook, Alan, Blanke, Charles, O’Reilly, Eileen M, Shields, Anthony F

“…IMPORTANCE: Aspirin and cyclooxygenase 2 (COX-2) inhibitors have been associated with a reduced risk of colorectal polyps and cancer in observational and…”
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Efficacy of Preoperative mFOLFIRINOX vs mFOLFIRINOX Plus Hypofractionated Radiotherapy for Borderline Resectable Adenocarcinoma of the Pancreas: The A021501 Phase 2 Randomized Clinical Trial by Katz, Matthew H G, Shi, Qian, Meyers, Jeff, Herman, Joseph M, Chuong, Michael, Wolpin, Brian M, Ahmad, Syed, Marsh, Robert, Schwartz, Larry, Behr, Spencer, Frankel, Wendy L, Collisson, Eric, Leenstra, James, Williams, Terence M, Vaccaro, Gina, Venook, Alan, Meyerhardt, Jeffrey A, O'Reilly, Eileen M

“…National guidelines endorse treatment with neoadjuvant therapy for borderline resectable pancreatic ductal adenocarcinoma (PDAC), but the optimal strategy…”
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Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention by Lowery, Maeve A, Ptashkin, Ryan, Jordan, Emmet, Berger, Michael F, Zehir, Ahmet, Capanu, Marinela, Kemeny, Nancy E, O'Reilly, Eileen M, El-Dika, Imane, Jarnagin, William R, Harding, James J, D'Angelica, Michael I, Cercek, Andrea, Hechtman, Jaclyn F, Solit, David B, Schultz, Nikolaus, Hyman, David M, Klimstra, David S, Saltz, Leonard B, Abou-Alfa, Ghassan K

“…Various genetic driver aberrations have been identified among distinct anatomic and clinical subtypes of intrahepatic and extrahepatic cholangiocarcinoma, and…”
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Extensive and drastically different alpine lake changes on Asia's high plateaus during the past four decades by Zhang, Guoqing, Yao, Tandong, Piao, Shilong, Bolch, Tobias, Xie, Hongjie, Chen, Deliang, Gao, Yanhong, O'Reilly, Catherine M., Shum, C. K., Yang, Kun, Yi, Shuang, Lei, Yanbin, Wang, Weicai, He, You, Shang, Kun, Yang, Xiankun, Zhang, Hongbo

“…Asia's high plateaus are sensitive to climate change and have been experiencing rapid warming over the past few decades. We found 99 new lakes and extensive…”
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Effect of First-Line Chemotherapy Combined With Cetuximab or Bevacizumab on Overall Survival in Patients With KRAS Wild-Type Advanced or Metastatic Colorectal Cancer: A Randomized Clinical Trial by Venook, Alan P, Niedzwiecki, Donna, Lenz, Heinz-Josef, Innocenti, Federico, Fruth, Briant, Meyerhardt, Jeffrey A, Schrag, Deborah, Greene, Claire, O'Neil, Bert H, Atkins, James Norman, Berry, Scott, Polite, Blase N, O'Reilly, Eileen M, Goldberg, Richard M, Hochster, Howard S, Schilsky, Richard L, Bertagnolli, Monica M, El-Khoueiry, Anthony B, Watson, Peter, Benson, Al B, Mulkerin, Daniel L, Mayer, Robert J, Blanke, Charles

“…IMPORTANCE: Combining biologic monoclonal antibodies with chemotherapeutic cytotoxic drugs provides clinical benefit to patients with advanced or metastatic…”
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m2ABQ—a proposed refinement of the modified algorithm-based qualitative classification of osteoporotic vertebral fractures by Aaltonen, H. L., O’Reilly, M. K., Linnau, K. F., Dong, Q., Johnston, S. K., Jarvik, J. G., Cross, N. M.

“…Summary Currently, there is no reproducible, widely accepted gold standard to classify osteoporotic vertebral body fractures (OVFs). The purpose of this study…”
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Biomarker-Based Therapy in Pancreatic Ductal Adenocarcinoma: An Emerging Reality? by Krantz, Benjamin A, O'Reilly, Eileen M

“…Over the last decade, many of the major solid organ cancers have seen improvements in survival due to development of novel therapeutics and corresponding…”
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Randomized, Multicenter, Phase II Trial of Gemcitabine and Cisplatin With or Without Veliparib in Patients With Pancreas Adenocarcinoma and a Germline BRCA/PALB2 Mutation by O'Reilly, Eileen M, Lee, Jonathan W, Zalupski, Mark, Capanu, Marinela, Park, Jennifer, Golan, Talia, Tahover, Esther, Lowery, Maeve A, Chou, Joanne F, Sahai, Vaibhav, Brenner, Robin, Kindler, Hedy L, Yu, Kenneth H, Zervoudakis, Alice, Vemuri, Shreya, Stadler, Zsofia K, Do, Richard K G, Dhani, Neesha, Chen, Alice P, Kelsen, David P

“…Five percent to 9% of pancreatic ductal adenocarcinomas (PDACs) develop in patients with a germline or (g +) mutation. Phase IB data from a trial that used…”
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