Search Results - "O'REILLY, M"
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Rivaroxaban for Thromboprophylaxis in High-Risk Ambulatory Patients with Cancer
Published in The New England journal of medicine (21-02-2019)“…A placebo-controlled trial assessed the efficacy of rivaroxaban to prevent venous thrombosis in patients with cancer at high risk for thrombosis. The…”
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2
NALIRIFOX in the frontline for metastatic pancreatic cancer: evidence beyond NAPOLI 3
Published in Nature reviews. Clinical oncology (25-10-2024)Get full text
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3
Widespread loss of lake ice around the Northern Hemisphere in a warming world
Published in Nature climate change (01-03-2019)“…Ice provides a range of ecosystem services—including fish harvest 1 , cultural traditions 2 , transportation 3 , recreation 4 and regulation of the…”
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4
Preoperative Treatment of Locally Advanced Rectal Cancer
Published in The New England journal of medicine (27-07-2023)“…In a trial comparing preoperative chemoradiotherapy and FOLFOX in patients with rectal cancer undergoing sphincter-sparing surgery, 5-year disease-free…”
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5
Neuromas as the cause of pain in the residual limbs of amputees. An ultrasound study
Published in Clinical radiology (01-10-2016)“…Aim To explore the morphology of neuromas and to determine the differences, if any, between asymptomatic and symptomatic neuromas using ultrasound. Materials…”
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Ultrasound-responsive droplets for therapy: A review
Published in Journal of controlled release (10-01-2019)“…The last two decades have seen the development of acoustically activated droplets, also known as phase-change emulsions, from a diagnostic tool to a…”
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7
Pancreatic cancer—A disease in need: Optimizing and integrating supportive care
Published in Cancer (15-11-2019)“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy that continues to be challenging to treat. PDAC has the lowest 5‐year relative survival…”
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8
Atlantic Diabetes in Pregnancy (DIP): the prevalence and outcomes of gestational diabetes mellitus using new diagnostic criteria
Published in Diabetologia (01-07-2011)“…Aims/hypothesis New diagnostic criteria for gestational diabetes mellitus (GDM) have recently been published. We wished to evaluate what impact these new…”
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Tumour response to TRK inhibition in a patient with pancreatic adenocarcinoma harbouring an NTRK gene fusion
Published in Annals of oncology (01-11-2019)“…Although rare, NTRK gene fusions are known to be oncogenic drivers in pancreatic ductal adenocarcinoma (PDAC). We report the response of a metastatic…”
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10
Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations
Published in Clinical cancer research (15-03-2018)“…Immune checkpoint inhibition has been shown to generate profound and durable responses in mismatch repair deficient (MMR-D) solid tumors and has elicited…”
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11
Perspectives on Euler angle singularities, gimbal lock, and the orthogonality of applied forces and applied moments
Published in Multibody system dynamics (15-09-2018)“…Coordinate singularities and gimbal lock are two phenomena that present themselves in models for the dynamics of mechanical systems. The former phenomenon…”
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12
Increased winter drownings in ice-covered regions with warmer winters
Published in PloS one (18-11-2020)“…Winter activities on ice are culturally important for many countries, yet they constitute a high safety risk depending upon the stability of the ice. Because…”
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13
Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer
Published in Nature (London) (01-06-2023)“…Pancreatic ductal adenocarcinoma (PDAC) is lethal in 88% of patients 1 , yet harbours mutation-derived T cell neoantigens that are suitable for vaccines 2 , 3…”
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Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (06-04-2021)“…IMPORTANCE: Aspirin and cyclooxygenase 2 (COX-2) inhibitors have been associated with a reduced risk of colorectal polyps and cancer in observational and…”
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Efficacy of Preoperative mFOLFIRINOX vs mFOLFIRINOX Plus Hypofractionated Radiotherapy for Borderline Resectable Adenocarcinoma of the Pancreas: The A021501 Phase 2 Randomized Clinical Trial
Published in JAMA oncology (01-09-2022)“…National guidelines endorse treatment with neoadjuvant therapy for borderline resectable pancreatic ductal adenocarcinoma (PDAC), but the optimal strategy…”
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Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention
Published in Clinical cancer research (01-09-2018)“…Various genetic driver aberrations have been identified among distinct anatomic and clinical subtypes of intrahepatic and extrahepatic cholangiocarcinoma, and…”
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Extensive and drastically different alpine lake changes on Asia's high plateaus during the past four decades
Published in Geophysical research letters (16-01-2017)“…Asia's high plateaus are sensitive to climate change and have been experiencing rapid warming over the past few decades. We found 99 new lakes and extensive…”
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Effect of First-Line Chemotherapy Combined With Cetuximab or Bevacizumab on Overall Survival in Patients With KRAS Wild-Type Advanced or Metastatic Colorectal Cancer: A Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (20-06-2017)“…IMPORTANCE: Combining biologic monoclonal antibodies with chemotherapeutic cytotoxic drugs provides clinical benefit to patients with advanced or metastatic…”
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19
m2ABQ—a proposed refinement of the modified algorithm-based qualitative classification of osteoporotic vertebral fractures
Published in Osteoporosis international (01-01-2023)“…Summary Currently, there is no reproducible, widely accepted gold standard to classify osteoporotic vertebral body fractures (OVFs). The purpose of this study…”
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Biomarker-Based Therapy in Pancreatic Ductal Adenocarcinoma: An Emerging Reality?
Published in Clinical cancer research (15-05-2018)“…Over the last decade, many of the major solid organ cancers have seen improvements in survival due to development of novel therapeutics and corresponding…”
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