Search Results - "O'Quinn, Michael P"
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A Peptide Mimetic of the Connexin43 Carboxyl Terminus Reduces Gap Junction Remodeling and Induced Arrhythmia Following Ventricular Injury
Published in Circulation research (18-03-2011)“…RATIONALE:Remodeling of connexin (Cx)43 gap junctions (GJs) is linked to ventricular arrhythmia. OBJECTIVES:A peptide mimetic of the carboxyl terminal (CT) of…”
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Cryoinjury models of the adult and neonatal mouse heart for studies of scarring and regeneration
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2013)“…A major limitation in studies of the injured heart is animal-to-animal variability in wound size resulting from commonly used techniques such as left anterior…”
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Epicardial injection of nanoformulated calcium into cardiac ganglionic plexi suppresses autonomic nerve activity and postoperative atrial fibrillation
Published in Heart rhythm (01-04-2019)“…Imbalanced activation of the cardiac autonomic nervous system triggers postoperative atrial fibrillation (POAF). Neuronal calcium overload induces apoptosis…”
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Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding
Published in Regenerative medicine (01-03-2009)“…Gap-junctional connexin43 (Cx43) has roles in multiple aspects of skin wound healing - including scarring. The aim here was to study the effects of a…”
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ZO-1 determines adherens and gap junction localization at intercalated disks
Published in American journal of physiology. Heart and circulatory physiology (01-02-2011)“…The disruption of the spatial order of electromechanical junctions at myocyte-intercalated disks (ICDs) is a poorly understood characteristic of many cardiac…”
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Cardiac arrest due to ventricular fibrillation in a 23-year-old woman with broken heart syndrome
Published in Cardiovascular pathology (01-09-2017)“…Broken heart syndrome, also known as takotsubo cardiomyopathy, is a syndrome characterized by a transient regional systolic dysfunction of the left ventricle…”
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Cardiac lymphoma presenting as bradyarrhythmia
Published in HeartRhythm case reports (01-07-2022)Get full text
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Approach to Management of Premature Ventricular Contractions
Published in Current treatment options in cardiovascular medicine (01-10-2019)“…Purpose of review Premature ventricular contractions (PVCs) are arrhythmias with presentation ranging from asymptomatic and benign to symptomatic, frequent and…”
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GATA6 reporter gene reveals myocardial phenotypic heterogeneity that is related to variations in gap junction coupling
Published in American journal of physiology. Heart and circulatory physiology (01-11-2011)“…This study examined transgenic mice whose expression of a β-galactosidase (lacZ) reporter is driven by a GATA6 gene enhancer. Previous investigations…”
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Cardiac lymphoma presenting as bradyarrhythmia
Published in HeartRhythm case reports (01-07-2022)Get full text
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