Search Results - "O'Neill, M. J"
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Induction of labour in nulliparous women with an unfavourable cervix: a randomised controlled trial comparing double and single balloon catheters and PGE2 gel
Published in BJOG : an international journal of obstetrics and gynaecology (01-10-2009)“…Objective To compare the efficacy and patient satisfaction of three methods of labour induction (double balloon catheters, single balloon catheters and…”
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Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease
Published in NeuroImage (Orlando, Fla.) (15-01-2016)“…Increased hyperphosphorylated tau and the formation of intracellular neurofibrillary tangles are associated with the loss of neurons and cognitive decline in…”
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Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease
Published in NeuroImage (Orlando, Fla.) (01-10-2017)“…Alzheimer's disease is connected to a number of other neurodegenerative conditions, known collectively as ‘tauopathies’, by the presence of aggregated tau…”
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Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease
Published in British journal of pharmacology (01-08-2010)“…Background and purpose: Increased glutamatergic innervation of the substantia nigra pars reticulata (SNpr) and pars compacta (SNpc) may contribute to the…”
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Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system
Published in Journal of controlled release (28-05-2013)“…Inflammatory bowel disease (IBD) is a chronic relapsing inflammation of the gastrointestinal tract. The cytokine TNF-alpha (TNF-α) plays a pivotal role in…”
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6
Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment
Published in Neuroscience (2004)“…Recent studies indicate that brain-derived neurotrophic factor (BDNF) may be implicated in the clinical action of antidepressant drugs. Repeated (2–3 weeks)…”
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Differential effects of NMDA antagonists on high frequency and gamma EEG oscillations in a neurodevelopmental model of schizophrenia
Published in Neuropharmacology (01-03-2012)“…Neuroanatomical, electrophysiological and behavioural abnormalities following timed prenatal methylazoxymethanol acetate (MAM) treatment in rats model changes…”
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Evaluation of Cellular Uptake and Gene Transfer Efficiency of Pegylated Poly-l-lysine Compacted DNA: Implications for Cancer Gene Therapy
Published in Molecular pharmaceutics (01-11-2006)“…Recent success in phase I/II clinical trials (Konstan, M. W.; Davis, P. B.; Wagener, J. S.; Hilliard, K. A.; Stern, R. C.; Milgram, L. J.; Kowalczyk, T. H.;…”
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The adenosine A2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism
Published in Behavioural brain research (05-01-2004)“…Recent evidence indicates that adenosine A2A receptors modulate the activity of striatal neurons, and that antagonists of this receptor may have actions in…”
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Prevalence and distribution of adnexal findings suggesting endometriosis in patients with MR diagnosis of adenomyosis
Published in British journal of radiology (01-04-2006)“…The purpose of this investigation was to establish the prevalence and distribution of MR findings associated with pelvic endometriosis in patients with a MRI…”
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Undermethylation associated with retroelement activation and chromosome remodelling in an interspecific mammalian hybrid
Published in Nature (London) (07-05-1998)“…Genetic models, predict that genomic rearrangement in hybrids can facilitate reproductive isolation and the formation of new species by preventing gene flow…”
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Tunneled Peritoneal Catheter Placement Under Sonographic and Fluoroscopic Guidance in the Palliative Treatment of Malignant Ascites
Published in American journal of roentgenology (1976) (01-09-2001)“…We present a treatment for recurrent, symptomatic ascites in patients with malignant disease. This report summarizes our experience with percutaneous tunneled…”
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13
Nosocomial infections during extracorporeal membrane oxygenation
Published in Intensive care medicine (01-08-2001)“…To examine trends in nosocomial infection associated with Extracorporeal Membrane Oxygenation (ECMO). Retrospective review of all patients who underwent ECMO…”
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Genetic and epigenetic incompatibilities underlie hybrid dysgenesis in Peromyscus
Published in Nature genetics (01-05-2000)“…Crosses between the two North American rodent species Peromyscus polionotus (PO) and Peromyscus maniculatus (BW) yield parent-of-origin effects on both…”
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Differences in the BOLD fMRI response to direct and indirect cortical stimulation in the rat
Published in Magnetic resonance in medicine (01-05-2003)“…Functional MRI (fMRI) exploits a relationship between neuronal activity, metabolism, and cerebral blood flow to functionally map the brain. We have developed a…”
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In vivo imaging of tau pathology using multi-parametric quantitative MRI
Published in NeuroImage (Orlando, Fla.) (01-05-2015)“…As the number of people diagnosed with Alzheimer's disease (AD) reaches epidemic proportions, there is an urgent need to develop effective treatment strategies…”
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Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: investigations into possible mechanism of action in vivo
Published in The Journal of pharmacology and experimental therapeutics (01-09-2000)“…The mechanisms underlying the neuroprotective effects of the group II metabotropic glutamate receptor (mGluR) agonist LY379268 were investigated in a gerbil…”
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NMDA receptor antagonism, but not AMPA receptor antagonism attenuates induced ischaemic tolerance in the gerbil hippocampus
Published in European journal of pharmacology (10-09-1999)“…Recent studies have shown that a brief `pre-conditioning' ischaemic insult reduces the hippocampal cell death caused by a subsequent more severe test insult…”
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Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia
Published in European journal of pharmacology (29-08-1996)“…To evaluate the role played by nitric oxide in global cerebral ischaemia we examined the effects of 7-nitroindazole and a sodium salt of 7-nitroindazole…”
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Peromyscus maniculatus--Mus musculus chromosome homology map derived from reciprocal cross species chromosome painting
Published in Cytogenetic and genome research (01-08-2008)“…The Mus musculus and Rattus norvegicus genomes have been extensively studied, yet despite the emergence of Peromyscus maniculatus as an NIH model for genome…”
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