Search Results - "O'Neill, Eoghan"

Eradication of Staphylococcus aureus Biofilm Infections Using Synthetic Antimicrobial Peptides by Zapotoczna, Marta, Forde, Éanna, Hogan, Siobhan, Humphreys, Hilary, O'Gara, James P, Fitzgerald-Hughes, Deirdre, Devocelle, Marc, O'Neill, Eoghan

“…Here, we demonstrate that antimicrobial peptides (AMPs) are an effective antibiofilm treatment when applied as catheter lock solutions (CLSs) against S. aureus…”
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Methicillin resistance and the biofilm phenotype in Staphylococcus aureus by McCarthy, Hannah, Rudkin, Justine K, Black, Nikki S, Gallagher, Laura, O'Neill, Eoghan, O'Gara, James P

“…Antibiotic resistance and biofilm-forming capacity contribute to the success of Staphylococcus aureus as a human pathogen in both healthcare and community…”
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A Novel Staphylococcus aureus Biofilm Phenotype Mediated by the Fibronectin-Binding Proteins, FnBPA and FnBPB by O'Neill, Eoghan, Pozzi, Clarissa, Houston, Patrick, Humphreys, Hilary, Robinson, D Ashley, Loughman, Anthony, Foster, Timothy J, O'Gara, James P

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Association between Methicillin Susceptibility and Biofilm Regulation in Staphylococcus aureus Isolates from Device-Related Infections by O'NEILL, Eoghan, POZZI, Clarissa, HOUSTON, Patrick, SMYTH, Davida, HUMPHREYS, Hilary, ASHLEY ROBINSON, D, O'GARA, James P

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5-Hydroxyethyl-3-tetradecanoyltetramic acid represents a novel treatment for intravascular catheter infections due to Staphylococcus aureus by Zapotoczna, Marta, Murray, Ewan J, Hogan, Siobhan, O'Gara, James P, Chhabra, Siri R, Chan, Weng C, O'Neill, Eoghan, Williams, Paul

“…Biofilm infections of intravascular catheters caused by Staphylococcus aureus may be treated with catheter lock solutions (CLSs). Here we investigated the…”
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Type I Tobit Bayesian Additive Regression Trees for censored outcome regression by O’Neill, Eoghan

“…Censoring occurs when an outcome is unobserved beyond some threshold value. Methods that do not account for censoring produce biased predictions of the…”
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Novel anti-staphylococcal and anti-biofilm properties of two anti-malarial compounds: MMV665953 {1-(3-chloro-4-fluorophenyl)-3-(3,4-dichlorophenyl)urea} and MMV665807 {5-chloro-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide} by Zapotoczna, Marta, Boksmati, Nabila, Donohue, Sinead, Bahtiar, Baizurina, Boland, Ahmad, Somali, Hamzah Al, Cox, Alysia, Humphreys, Hilary, O'Gara, James P, Brennan, Marian, O'Neill, Eoghan

“…The treatment of device-related infections is challenging and current anti-microbial compounds have poor anti-biofilm activity. We aimed to identify and…”
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Untangling the Diverse and Redundant Mechanisms of Staphylococcus aureus Biofilm Formation by Zapotoczna, Marta, O'Neill, Eoghan, O'Gara, James P

“…Other protein adhesins include the cell wall-anchored clumping factor A (ClfA), cell wall-anchored clumping factor B (ClfB), S. aureus surface protein G…”
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Hand hygiene compliance by visitors to hospitals—can we do better? by Wolfe, Rebecca, BEng, O'Neill, Eoghan, MB, BCh, BAO, PhD

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Carriage of both the fnbA and fnbB genes and growth at 37 {degrees}C promote FnBP-mediated biofilm development in meticillin-resistant Staphylococcus aureus clinical isolates by O'Neill, Eoghan, Humphreys, Hilary, O'Gara, James P

“…1 UCD School of Biomolecular and Biomedical Science, Ardmore House, University College Dublin, Belfield, Dublin 4, Ireland 2 Department of Clinical…”
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The Effect of Rapid Screening for Methicillin‐Resistant Staphylococcus aureus (MRSA) on the Identification and Earlier Isolation of MRSA‐Positive Patients by Creamer, Eilish, Dolan, Anthony, Sherlock, Orla, Thomas, Toney, Walsh, John, Moore, Joan, Smyth, Edmond, O’Neill, Eoghan, Shore, Anna, Sullivan, Derek, Rossney, Angela S., Cunney, Robert, Coleman, David, Humphreys, Hilary

“…(1) To determine whether rapid screening with polymerase chain reaction (PCR) assays leads to the earlier isolation of patients at risk for…”
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Strain Hardening From Elastic-Perfectly Plastic to Perfectly Elastic Indentation Single Asperity Contact by Ghaednia, Hamid, Mifflin, Gregory, Lunia, Priyansh, O'Neill, Eoghan O., Brake, Matthew R. W.

“…Indentation measurements are a crucial technique for measuring mechanical properties. Although several contact models have been developed to relate…”
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Metabolic reprogramming and altered cell envelope characteristics in a pentose phosphate pathway mutant increases MRSA resistance to β-lactam antibiotics by Zeden, Merve S, Gallagher, Laura A, Bueno, Emilio, Nolan, Aaron C, Ahn, Jongsam, Shinde, Dhananjay, Razvi, Fareha, Sladek, Margaret, Burke, Órla, O'Neill, Eoghan, Fey, Paul D, Cava, Felipe, Thomas, Vinai C, O'Gara, James P

“…Central metabolic pathways control virulence and antibiotic resistance, and constitute potential targets for antibacterial drugs. In Staphylococcus aureus the…”
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Impaired Alanine Transport or Exposure to d-Cycloserine Increases the Susceptibility of MRSA to β-lactam Antibiotics by Gallagher, Laura A, Shears, Rebecca K, Fingleton, Claire, Alvarez, Laura, Waters, Elaine M, Clarke, Jenny, Bricio-Moreno, Laura, Campbell, Christopher, Yadav, Akhilesh K, Razvi, Fareha, O’Neill, Eoghan, O’Neill, Alex J, Cava, Felipe, Fey, Paul D, Kadioglu, Aras, O’Gara, James P

“…Abstract Prolonging the clinical effectiveness of β-lactams, which remain first-line antibiotics for many infections, is an important part of efforts to…”
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The impact of increasing antimicrobial resistance in the treatment of urosepsis by Ryan, James, McLornan, Liza, O’Neill, Eoghan

“…Background and aims Urosepsis accounts for up to 20–30% of all sepsis cases; however, increasing antimicrobial resistance is posing a significant threat to…”
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Urosepsis and the urologist by Ryan, James, O'Neill, Eoghan, McLornan, Liza

“…Sepsis is a life-threatening organ dysfunction that is caused by a dysregulated host response to the infection. Urosepsis contributes up to 25% of all sepsis…”
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Can e-learning improve the performance of undergraduate medical students in Clinical Microbiology examinations? by Stevens, Niall T, Holmes, Killian, Grainger, Rachel J, Connolly, Roisín, Prior, Anna-Rose, Fitzpatrick, Fidelma, O'Neill, Eoghan, Boland, Fiona, Pawlikowska, Teresa, Humphreys, Hilary

“…Clinical Microbiology is a core subject in medical undergraduate curricula. However, students struggle to cover the content and clinically contextualise basic…”
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The microbial etiology and resistance patterns of cosmetic tourism-related infections in Ireland by Keane, Andrew, Feeley, Aoife A, Chee, Shu Ying, Sheil, Fiachra, O'Gorman, Joanne, O'Neill, Eoghan, Cahill, Kevin C

“…Cosmetic tourism is an increasingly common phenomenon, both in Ireland and internationally. Complications associated with procedures performed abroad may…”
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Impact of Recommendations by Clinical Microbiologists on Antimicrobial Treatment in the Intensive Care Units of a Dublin Teaching Hospital by O'Neill, Eoghan, Humphreys, Hilary, Smyth, Edmond

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Hospital Outcomes in Patients Hospitalized for COVID-19 Pneumonia: The Effect of SARS-CoV-2 Vaccination and Vitamin D Status by Sanecka, Martyna, Youssef, Modar, Abdulsalam, Mohammad, Raza, Syed F, Qadeer, Abdul, Ioana, Julia, Aldoresi, Alya, Shah, Syed I, Al Lawati, Abdul, Feely, Joseph, Tormey, William P, O'Neill, Eoghan, Cormican, Liam J, Judge, Eoin P, McCartney, Daniel M A, Faul, John L

“…SARS-CoV-2 vaccination promises to improve outcomes for patients with COVID-19 pneumonia (most notably those with advanced age and at high risk for severe…”
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