Search Results - "O'Neil, N J"

The sterol modifying enzyme LET-767 is essential for growth, reproduction and development in Caenorhabditis elegans by Kuervers, L M, Jones, C L, O'Neil, N J, Baillie, D L

“…The let-767 gene encodes a protein that is similar to mammalian steroid enzymes that are responsible for the reduction of 17-beta hydroxysteroid hormones…”
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iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human by Lu, Xin, Bergamaschi, Daniele, Samuels, Yardena, O'Neil, Nigel J, Trigiante, Giuseppe, Crook, Tim, Hsieh, Jung-Kuang, O'Connor, Daniel J, Zhong, Shan, Campargue, Isabelle, Tomlinson, Matthew L, Kuwabara, Patricia E

“…We have previously shown that ASPP1 and ASPP2 are specific activators of p53; one mechanism by which wild-type p53 is tolerated in human breast carcinomas is…”
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Identification and characterization of a serine hydroxymethyltransferase isoform in Caenorhabditis briggsae by Vatcher, G.P., Barbazuk, W.B., O'Neil, N.J., Marra, M.A., Ha, T., Baillie, D.L.

“…In the nematode Caenorhabditis elegans, the maternal effect lethal gene mel-32 encodes a serine hydroxymethyltransferase isoform. Since interspecies DNA…”
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RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination by Barber, Louise J., Youds, Jillian L., Ward, Jordan D., McIlwraith, Michael J., O'Neil, Nigel J., Petalcorin, Mark I.R., Martin, Julie S., Collis, Spencer J., Cantor, Sharon B., Auclair, Melissa, Tissenbaum, Heidi, West, Stephen C., Rose, Ann M., Boulton, Simon J.

“…Homologous recombination (HR) is an important conserved process for DNA repair and ensures maintenance of genome integrity. Inappropriate HR causes gross…”
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Differential modulation of surface and intracellular protein expression by T cells after stimulation in the presence of monensin or brefeldin A by O'Neil-Andersen, Nancy J, Lawrence, David A

“…Intracellular cytokine staining is an increasingly popular analytical tool that can be used to define the profile of cytokines in various disease states. One…”
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Homologous Recombination Is Required for Genome Stability in the Absence of DOG-1 in Caenorhabditis elegans by Youds, Jillian L, O'Neil, Nigel J, Rose, Ann M

“…In C. elegans, DOG-1 prevents deletions that initiate in polyG/polyC tracts (G/C tracts), most likely by unwinding secondary structures that can form in G/C…”
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RNA-mediated interference as a tool for identifying drug targets by O'Neil, N J, Martin, R L, Tomlinson, M L, Jones, M R, Coulson, A, Kuwabara, P E

“…The nematode Caenorhabditis elegans is the first multicellular organism with a fully sequenced genome. As a model organism, C. elegans is playing a special…”
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Lethal mutations defining 112 complementation groups in a 4.5 Mb sequenced region of Caenorhabditis elegans chromosome III by Stewart, H I, O'Neil, N J, Janke, D L, Franz, N W, Chamberlin, H M, Howell, A M, Gilchrist, E J, Ha, T T, Kuervers, L M, Vatcher, G P, Danielson, J L, Baillie, D L

“…The central gene cluster of chromosome III was one of the first regions to be sequenced by the Caenorhabditis elegans genome project. We have performed an…”
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Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1 by Astin, Jonathan W., O’Neil, Nigel J., Kuwabara, Patricia E.

“…The Caenorhabditis elegans rad-3 gene was identified in a genetic screen for radiation sensitive (rad) mutants. Here, we report that the UV sensitivity of…”
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Spectrum of mutational events in the absence of DOG-1/FANCJ in Caenorhabditis elegans by Zhao, Yang, Tarailo-Graovac, Maja, O’Neil, Nigel J., Rose, Ann M.

“…The Caenorhabditis elegans ortholog of the Fanconi anemia pathway component J (FANCJ) is DOG-1, which is essential for genome stability. Previous studies have…”
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Interpreting a sequenced genome: toward a cosmid transgenic library of Caenorhabditis elegans by Janke, D L, Schein, J E, Ha, T, Franz, N W, O'Neil, N J, Vatcher, G P, Stewart, H I, Kuervers, L M, Baillie, D L, Rose, A M

“…We have generated a library of transgenic Caenorhabditis elegans strains that carry sequenced cosmids from the genome of the nematode. Each strain carries an…”
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CD4 super(+)CD25 super(h) super(i) super(g) super(h) T cell numbers are enriched in the peripheral blood of patients with rheumatoid arthritis by Han, G M, O'Neil-Andersen, N J, Zurier, R B, Lawrence, DA

“…Accumulating evidences support that CD4 super(+)CD25 super(h) super(i) super(g) super(h) T regulatory (Treg) cells play an essential role in controlling and…”
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Psychosocial vulnerability, hostility, and family history of coronary heart disease among male and female college students by O'Neil, John N, Emery, Charles F

“…This study evaluated the utility of the psychosocial vulnerability model for understanding the hostility-coronary heart disease (CHD) relationship among…”
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